Ischemia

Our PhD student, Johanna Augros, represented our lab exceptionally well at the International Society on Thrombosis and Haemostasis @isth.org meeting that took place in Washington. See you next year at the ISTH next meeting in Paris!

Members of INSERM UMR1327 Ischemia: Mohammed ELMALLAH, Marylou PICHONNIERE and Oumnia BENOUNA were pleased to present their work yesterday, at the Annual meeting of the @frenchpurine.bsky.social in Paris. A meeting enriched by relevant scientific discussions.

We thank the organizers of the PRESTO COST action meeting (Dublin, Ireland, 22-24/05), on the topic "Purinergic signalling: from bench-to-bedside, where are we now?"

Congratulations to our unit members W. ECHCHIH, M. PICHONNIERE, M. ElMALLAH, A. HERAUD-MELEY and O. BENOUNA for their presentations.

Les anticorps monoclonaux dans les maladies immuno-inflammatoires | G. Paintaud, O. Le Tilly, D. Ternant, C. Desvignes, T. Bejan-Angoulvant En 26 ans, 44 anticorps monoclonaux (AcMo), se fixant sur 28 antigènes cibles différents, ont obtenu une indication dans au moins une maladie immuno-inf

Synthèse sur "Les anticorps monoclonaux dans les maladies immuno-inflammatoires" dans le dernier N° de La Lettre du Pharmacologue, consacré à la pharmacologie de l'inflammation

par G. Paintaud, O. Le Tilly, D. Ternant, C. Desvignes et @theodorabejan.bsky.social

www.edimark.fr/revues/la-le...

Yesterday, Oumnia Benouna, Ana Valéria Vinhais da Silva, Johanna Augros, Marylou Pichonnière, Claire Hosemans and Wiam Echchih (UMR1327), participated to a 10 km "Parcours du cœur" at Bergeonnerie Lake (Tours), a walk dedicated to raising awareness about heart health.

Thanks to the organizers!

Découvrez les planches de la nouvelle édition "Ma thèse en BD" (2024-25) Suite à un appel à participation lancé en septembre dernier, 5 doctorants et doctorantes ont été sélectionnés pour la 3e édition de 'Ma thèse en BD'. Le défi : illustrer ses travaux de recherche et so...

Nous avons le plaisir de participer au programme "Ma thèse en BD" de l'université de Tours.

Les planches 2024-2025, réalisées par 3 dessinatrices/teurs avec 5 doctorant.es, sont téléchargeables et feront l'objet de plusieurs expos, notamment lors du festival 2025

saps.univ-tours.fr/decouvrez-le...

Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy npj Digital Medicine - Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy

Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy

Denis Angoulvant @dangoulvant.bsky.social is coauthor of this paper by Yishu Wang et al., published in NPJ Digit Med

rdcu.be/ehav0

Prognosis of patients with acute myocardial infarction in the setting of COVID-19: A French nationwide observational study The prognosis of patients with acute myocardial infarction (AMI) in the setting of coronavirus disease 2019 (COVID-19) remains uncertain.To evaluate p…

Prognosis of patients with acute myocardial infarction in the setting of COVID-19: A French nationwide observational study

by Ahmad Abou Hamed, Maeva Gourraud, Thibaud Genet, François Barbier, Denis Angoulvant, Laurent Fauchier and Fabrice Ivanes

www.sciencedirect.com/science/arti...

Conférences Sport & Santé
le 21 mars à MAME (Tours) à 17h30

Un événement organisé par Tours Autogreffe

Nous sommes à la recherche de candidat.es pour notre poste d'Assistant Hospitalo-universitaire, qui sera disponible en novembre 2025.

Contacts : Theodora Bejan-Angoulvant @theodorabejan.bsky.social ou David Ternant

Merci de reposter !

Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes:
protocol for a nationwide observational comparative study in routine care
bmjopen.bmj.com/content/15/1...

Bevacizumab-based chemotherapy adaptive to pharmacokinetic of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized ph... Bevacizumab shows inter-individual pharmacokinetic variability, with an exposure-response relationship in metastatic colorectal cancer (mCRC) patients…

Publication of the PHARBEVACOL study protocol:
Bevacizumab-based chemotherapy adaptive to PK of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized phase III trial study
www.sciencedirect.com/science/arti...

Bonjour, une action est signalée à Tours : standupforscience.fr/tous-les-eve... 👍

Outcomes in Atrial Fibrillation Patients with Different Clinical Phenotypes: Insights from the French Population Background: Atrial fibrillation (AF) patients represent a clinically complex, heterogeneous population comprising multiple homogeneous cohorts. Purpose: We aimed to identify the common clinical phenot...

Outcomes in Atrial Fibrillation Patients with Different Clinical Phenotypes: Insights from the French Population

by A.M. Fawzy, A. Bisson, L. Lochon, T. Lenormand, G.Y.H. Lip and L. Fauchier

@liverpoolccs.bsky.social @chrudetours.bsky.social @chuorleans.bsky.social
www.mdpi.com/3171158

Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUAT... Antithrombotic management in patients with chronic coronary syndrome and previous stent implantation who require long-term oral anticoagulation is hig…

@dangoulvant.bsky.social is coauthor of

Quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial
www.sciencedirect.com/science/arti...

Thrombotic Microangiopathy From Peptide Receptor Radionuclide Therapy

TMA from peptide receptor radionuclide therapy

P Delalande, M Bobot, M Essig, C Simon, AP Jonville-Béra, C Barbet, B Sautenet, V Maisons, T Carsuzaa, F Bruyère and JM Halimi

@aphm-chu-marseille.bsky.social @hopambroisepare.bsky.social @chrudetours.bsky.social

www.sciencedirect.com/science/arti...

Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes Arnaud Bisson, Denis Angoulvant; Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes, European Journal o

Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes

in Eur J Prev Cardiol 2025

by A. Bisson and D. Angoulvant, Inserm UMR1327 and Departments of Cardiology of @chrudetours.bsky.social and @chuorleans.bsky.social

academic.oup.com/eurjpc/artic...

Imaging flow cytometry as a novel approach for the diagnosis of heparin‐induced thrombocytopenia Imaging flow cytometry (IFC) combines the advantages of flow cytometry (FC) and microscopy to provide detailed morphological insights into platelets. In this study, we evaluated the performance of mo...

Imaging flow cytometry for the diagnosis of HIT

by Carré J, Demont Y, Mouton C, Vayne C, Guéry EA, Voyer A, Garçon L, Le Guyader M, Demagny J
@chuamiens.bsky.social @chu-bordeaux.fr @chrudetours.bsky.social
in Br J Haematol 2025 @bsochaem.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...

3e Journées Scientifiques du French Purine Club ESPCI, 10 rue Vauquelin, 75005 Paris

Nous avons le plaisir de vous inviter aux 3ᵉ Journées Scientifiques du French Purine Club !
📅 30 juin à 14h au 1er juillet à 12h
📍 ESPCI, 10 rue Vauquelin, 75005 Paris
🔗 docs.google.com/forms/d/e/1F...

💡 Pensez aussi à votre cotisation annuelle
➡️ bit.ly/4hOcar6

Nous espérons vous y voir nombreux !

A clinician viewpoint on the 2024 European guidelines on the management of patients with atrial fibrillation

A clinician viewpoint on the 2024 European guidelines on the management of patients with atrial fibrillation

by L Fauchier UMR1327 and @chrudetours.bsky.social, JC Deharo @aphm-chu-marseille.bsky.social, F Sacher @chu-bordeaux.fr and A Cohen @ap-hp.bsky.social
www.sciencedirect.com/science/arti...

Evaluation of efficacy and safety of rituximab in patients with progressive interstitial lung disease (ILD) with inflammatory component (EvER-ILD2): A multicentre double-blind placebo-controlled rando... NCT05596786 (clinicaltrials.gov), EU-CT number 2022-500,375-31-00 (European Medicines agency).

Evaluation of efficacy and safety of rituximab in patients with progressive interstitial lung disease with inflammatory component (EvER-ILD2): A multicentre double-blind placebo-controlled randomized trial

by M Ferreira, T Bejan-Angoulvant, S Marchand-Adam et al.
pubmed.ncbi.nlm.nih.gov/39693827/

P2 purinergic receptors at the heart of pathological left ventricular remodeling following acute myocardial infarction - PubMed Pathological left ventricular remodeling is a complex process following an acute myocardial infarction, leading to architectural disorganization of the cardiac tissue. This phenomenon is characterized...

P2 purinergic receptors at the heart of pathological left ventricular remodeling following acute myocardial infarction

a review by AV Vinhais da Silva, S Chesseron, O Benouna, J Rollin, S Roger, T Bourguignon, S Chadet and F Ivanes

Am J Physiol Heart Circ Physiol
pubmed.ncbi.nlm.nih.gov/39884315/