π Think all white matter (WM) astrocytes are the same? Think again! π Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. π§
www.nature.com/articles/s41...
@carleton-lab.bsky.social
Account for the Carleton and Rodriguez laboratories at the university of Geneva, Switzerland. rodriguez-carleton-labs.unige.ch Studying claustrum and cognitive dysfunctions in neuropsychiatric disorders.
π Think all white matter (WM) astrocytes are the same? Think again! π Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. π§
www.nature.com/articles/s41...
Thanks
03.12.2024 06:11 β π 0 π 0 π¬ 0 π 0Thank a monkey !
01.12.2024 17:38 β π 18 π 10 π¬ 0 π 0No idea but I hope someone will tell us!
22.11.2024 07:54 β π 1 π 0 π¬ 0 π 0Dive into our latest findings on this powerful structure here: βThe claustrum is critical for maintaining working memoryβ biorxiv.org/cgi/content/...
22.11.2024 07:50 β π 14 π 3 π¬ 0 π 1π‘ Our recent study suggests that the claustrum could be fundamental for maintaining working memory, supporting attention, cognitive control, and more!
22.11.2024 07:50 β π 3 π 0 π¬ 1 π 0β¨ New findings reveal something groundbreaking: the claustrum may be the essential working memory storage hub of the brain! Could it be the βRAMβ that cortical areas rely on for complex functions? #WorkingMemory #BrainResearch
22.11.2024 07:50 β π 6 π 1 π¬ 2 π 0Every year during neuroanatomy practical classes, medical students ask the same questions: "What is this structure located between the insula and the putamen? Is it part of the basal ganglia involved in motor control?
22.11.2024 07:36 β π 1 π 0 π¬ 1 π 0This work would not have been possible without the dedicated, collaborative efforts of my colleagues, Madlaina Boillat and Marie Moulinier, from the @carleton-lab.bsky.social labs. 9/9
19.11.2024 07:34 β π 1 π 1 π¬ 0 π 0We are hiring TWO Assistant Professors!!! Please share!!
neurojobs.sfn.org/job/38211/tw...
π§© Our findings provide a detailed cellular map of the claustro-insular region and offer new insights into how Nr4a2 regulates the molecular identity of its neurons.
www.biorxiv.org/content/10.1...
π This shift involved activating a transcription factor cascade, resulting in altered neuronal firing patterns. This suggests NR4A2 acts as a master regulator of claustrum neuron identities and influences their functional dynamics. β‘ #NeuronalFunction
18.11.2024 08:12 β π 0 π 0 π¬ 1 π 0π§ We focused on NR4A2, a gene linked to neuropsychiatric risk and highly expressed in the claustro-insular region. Using an Nr4a2 haploinsufficiency model, we found that only claustrum neurons showed shifts in molecular identity. π§© #Genetics
18.11.2024 08:12 β π 0 π 0 π¬ 1 π 0π§« By combining single-cell RNA sequencing with spatial transcriptomics, we created an atlas of the claustro-insular region in mice. This approach unveiled diverse neuronal subtypes and unexpected complexity. π #BrainAtlas
18.11.2024 08:12 β π 0 π 0 π¬ 1 π 0π The claustro-insular region: a critical but poorly understood part of the brain, known for its roles in attention, cognitive flexibility, interoception, and affective processing. Our recent research provides a new, high-resolution map of this fascinating area.
18.11.2024 08:12 β π 3 π 1 π¬ 1 π 0