Valentin Jaumouillé

Shout out to my post-doc adviser. An exceptional scientist, indeed.

Félicitations Véronique!

Definitely! See you there 😀

@mmorrissey.bsky.social's lab is on 🔥

Another awesome paper from @mmorrissey.bsky.social lab!

We look forward to hearing feedback from the community on our #preprint where we used #NETosis as a platform to show that chromatin decompaction inside the nucleus directly regulates cell mechanics. This work identifies long-range biophysical impacts of chromatin in mammalian cells.

Really excited about this! Lucy Shapiro pioneered research on the cell biology of bacteria and was a huge inspiration for my PhD project.

Our paper on podosome regulation by myosins 1e/f is now online.
We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬
Cool collaboration with @renaudpoincloux.bsky.social‬ and Krendel labs
www.sciencedirect.com/science/arti...

If you're interested in biophysics in the context of infection and immunity, we're looking forward to seeing you at the ASCB/EMBO meeting.

Screenshot of Essay from Martin Schwartz on 'Why would anyone want to be a scientist'. An anniversary article from The Company of Biologists published in Journal of Cell Science. The first few lines are: It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection. But, strange even to myself, I not only don't question the unfavorable risk-to-reward ratio but consider myself astonishingly lucky to be a scientist. There are three fundamental pleasures that have sustained me through 50 years of this madness.

Why would anyone want to be a scientist?

Check out our new Essay from Martin Schwartz: journals.biologists.com/jcs/article/...

Majority of fruit fly immunity studies can be replicated, huge analysis finds Verification of 50 years of data bolsters immunology research, but identifies “suspicious” papers that don’t hold up

Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...

Portrait of Fiona Brinkman, a smiling, middle-aged woman with jaw-length blonde hair and glasses wearing a grey blazer.

Congratulations to #SFU Molecular Biology and Biochemistry distinguished professor Fiona Brinkman who has received a @genomebc.bsky.social Award for Scientific Excellence from Life Sciences BC! www.sfu.ca/science/news...

Canada Excellence Research Chairs (CERC) 2026 Competition

SFU invites applications from world renowned researchers for the prestigious Canada Excellence Research Chairs (CERC) 2026 Competition. Please see the ad to see if you qualify. In Vancouver, BC
www.sfu.ca/vpacademic/a...

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...

Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation!

Read more at:

www.nature.com/articles/s41...

Somehow, I only started to realize this while I became a faculty member. Although, I wonder whether having a better awareness of these challenges would have been discouraging.

Excited to share our discovery www.science.org/doi/10.1126/...

that the #centrosome is prone to breakage!

Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin #forces, & prevented by #Dyrk3

Kudos to 1st author Madeleine & thanks to all collaborators!

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A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals T cell priming is characterized by an initial activation phase that involves stable interactions with dendritic cells (DCs). How activated T cells receive the paracrine signals required for their diff...

It used to be thought that T-cell priming occurred as single phase. Now we know it takes two.
www.science.org/doi/10.1126/...
@science.org

The Coming Out of a Transgender Scientist "I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

A crosstalk between adhesion and phagocytosis integrates macrophage functions into their microenvironment Cell biology; Organizational aspects of cell biology; Specialized functions of cells; Functional aspects of cell biology

I knew there would be an effect! This has been one of the questions that I had for the longest time. Changing the mechanics of the substrate affects phagocytosis. Very interesting paper!
www.cell.com/iscience/ful...

A TRPV4–dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration Cell migration is crucial for development and tissue homeostasis, while its dysregulation leads to severe pathologies. Cell migration is driven by the extension of actin–based lamellipodia protrusions...

Excited to share our latest work on how Ca²⁺ regulates actin in cell protrusions—now available as a preprint on bioRxiv! 🎉 Huge congrats to Ernest Iu for leading the project, and a special thanks to our amazing collaborators!

www.biorxiv.org/content/10.1...

Our latest publication on #macrophages congrats Anna Mularski and @manondepierre.bsky.social @institutcochin.bsky.social @actin-paris-saclay.bsky.social Martial Balland @grenoblealpes.bsky.social
@cnrsbiologie.bsky.social cnrs physique @anr

Wu et al @sickkidsto.bsky.social show that Snx10 regulates PI(3,5)P2 accumulation on #lysosomes by controlling PI(3)P delivery. Deleting Snx10 inhibits ClC-7, thereby impairing (phago)lysosome resolution. This mechanism may account for Snx10-related #osteopetrosis. rupress.org/jcb/article/...

Thanks!

Hi Esther, I'd like to be added, please.

In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...

A black-and-white photo shows a woman in a patterned dress with a lace collar and pearl necklace, sitting in a chair. The background features shelves with bottles and a wire basket, suggesting an early 20th-century setting, possibly a pharmacy or study.

On this day in 1879, Maud Menten was born in Port Lambton, Ontario.
In her work as a medical researcher, she became a leading expert in histochemistry and enzyme kinetics while fighting against sexism in her field.
Let's learn more about her life!

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YouTube video by yEFIS yEFIS Women in Immunology: Interview with Professor Johanna Joyce

Many thanks to the young immunologists of @yefis-immunology.bsky.social for this interview as part of their #WomeninSTEM 🧪 series!

Really enjoyed discussing ways to improve #gender #equality and all forms of #inclusion & #diversity - esp. important now 🙏

Interview 🎥
www.youtube.com/watch?v=4CRx...

YouTube video by Marine Biological Laboratory Polarized dual-view light sheet microscopy

A hybrid microscope born at the MBL allows scientists to, for the first time, simultaneously image the full 3D orientation and position of an ensemble of molecules. @czbiohub.bsky.social @hhmi.org @hhmijanelia.bsky.social @pnas.org

More: www.mbl.edu/news/new-mic...

www.youtube.com/watch?v=-b3X...

Revisiting 'Women in cancer research & oncology' 🧪⚕️

Thanks to Cancer Cell & @montse-rojo.bsky.social for this article from International Women's Day in 2021

It was great to be part of this perspective - and it all still applies in 2025 - here some thoughts on how much our microenvironment matters!

Hi Ankita, I'm glad to see your manuscript is out. It's an awesome study! Good luck with everything in these crazy times.