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3ehrendtLab

@3ehrendtlab.bsky.social

Nucleic Acid Immunity & Genome Defense https://maps.app.goo.gl/cET4bEWpvKCp9KDM6

34 Followers  |  42 Following  |  13 Posts  |  Joined: 17.12.2024  |  1.7574

Latest posts by 3ehrendtlab.bsky.social on Bluesky

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Postdoctoral fellow (m/w/d) โ€“ Sterile Inflammation & Epigenetics - Bonn, Nordrhein-Westfalen (DE) job with Universitรคtsklinikum Bonn | 12841086 The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, t...

We are hiring. Join us if you like the topic. Also, weโ€™re nice and dedicated people here @immunosens.bsky.social @unibonn.bsky.social ๐Ÿฅธ Exiting times ahead in #immunosky & #retroelements
Funded by @erc.europa.eu

www.nature.com/naturecareer...

05.07.2025 08:55 โ€” ๐Ÿ‘ 1    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Behrendt Group

You can check here

www.ukbonn.de/en/icccp/res...

04.07.2025 04:39 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

We are looking for a PostDoc in Immunity/ Epigenetics and Retroelements. Addโ€˜s out soon. Email me if you think you fit.
We are funded by @erc.europa.eu and a member of @immunosens.bsky.social @unibonn.bsky.social
#PostDoc #immunosky #bonn #germany

26.06.2025 06:09 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Postdoctoral fellow (m/f/d) โ€“ metabolic and nutritional regulation of immunity - Bonn, Nordrhein-Westfalen (DE) job with Universitรคtsklinikum Bonn | 12839421 Postdoctoral fellow (m/f/d) โ€“ metabolic and nutritional regulation of immunity

@labwilhelm.bsky.social is recruiting. Come to #Bonn and join @immunosens.bsky.social @unibonn.bsky.social
#immunosky

www.nature.com/naturecareer...

19.06.2025 11:03 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Excellence Strategy Funds Bonn Cluster for Immune Research The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and stateโ€ฆ

Hurray! ImmunoSensation will go on! ๐Ÿฅณ
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn ๐ŸŽ‰

www.immunosensation.de/news/immunos...

22.05.2025 15:55 โ€” ๐Ÿ‘ 44    ๐Ÿ” 11    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 5

@dfg.de just annouced that our excellence cluster @immunosens.bsky.social is funded. And @unibonn.bsky.social received 8 clusters in total making it the leading resarch university in Germany. Congratulations to everyone

www.dfg.de/resource/blo...

22.05.2025 16:45 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Systemic Inactivation of TREX1 Induces Selective Inflammation of the Tumor Microenvironment and Invigorated T Cell-Mediated Tumor Control Abstract. Therapeutic innate immune stimulation within the tumor microenvironment can potentiate endogenous antitumor T cell immunity. Strategies for controlled activation of cGAS/STING signaling are ...

Together with the Roers Lab from @uniheidelberg.bsky.social and @bms-us.bsky.social we propose that controlled low level systemic activation of #cGAS by endogenous nucleic acids is a safe and effective way to boost #cancer #immunotherapy.

aacrjournals.org/cancerres/ar...

21.05.2025 12:41 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿšจ Extended deadline! #Apply now for the 4th International School on Advanced Immunology!

The #school is hosted by our Cluster of @unibonn.bsky.social and Immunology Frontier Research Center (IFReC) of the Osaka University. ๐Ÿ‡ฏ๐Ÿ‡ต ๐Ÿ‡ฉ๐Ÿ‡ช

Visit our homepage for more information: www.advanced-immunology.net

20.05.2025 09:08 โ€” ๐Ÿ‘ 4    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Advertising flyer for the symposium, keynote lectures by Nadine Laguette from Montepellier (Crosstalk between DNA damage response and DNA sensing), Megan Stanifer from Florida (Lambda interferon in the gut epithelium) and Alessandra Mortellaro from Milano (type I interferons in hematopoiesis), plus local keynotes by Ana Martรญn-Villalba, Marieke Essers and Stefan Jordan.

Advertising flyer for the symposium, keynote lectures by Nadine Laguette from Montepellier (Crosstalk between DNA damage response and DNA sensing), Megan Stanifer from Florida (Lambda interferon in the gut epithelium) and Alessandra Mortellaro from Milano (type I interferons in hematopoiesis), plus local keynotes by Ana Martรญn-Villalba, Marieke Essers and Stefan Jordan.

Second Heidelberg Interferons Symposium coming up!! If you are based in HD or Mannheim (@dkfz.bsky.social, @uniheidelberg.bsky.social, @hlsalliance.bsky.social, @embl.org,...) and interested in any facet of these incredible #cytokines, join us on

๐Ÿ—“๏ธ July 10/11
๐Ÿซ Marsilius Kolleg
โœ๐Ÿป bit.ly/IFN2025

09.05.2025 09:10 โ€” ๐Ÿ‘ 14    ๐Ÿ” 15    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 2
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Arrived at my second hometown and very exited to join #HKS2025 hosted by @bogunoviclab.bsky.social and @jem.org #immunology #Belgrade #Serbia

10.04.2025 10:03 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Do the authors claim that the RNA is sensed directly by cGAS and induced catalytic activity or is cGAS activation an indirect effect?

26.03.2025 22:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Doesnโ€˜t look all to flat there ๐ŸŒ
#flatearth

20.03.2025 13:44 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Cytosolic nucleic acid sensing as driver of critical illness: mechanisms and advances in therapy - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Cytosolic nucleic acid sensing as driver of critical illness: mechanisms and advances in therapy

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Together with colleagues from @immunosens.bsky.social we reviewed the role of cytosolic nucleic acid sensing in critical illness.

www.nature.com/articles/s41...

19.03.2025 17:45 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The DNase TREX1 is a substrate of the intramembrane protease SPP with implications for disease pathogenesis - Cellular and Molecular Life Sciences Signal peptide peptidase (SPP) is an ER-resident aspartyl intramembrane protease cleaving proteins within type II-oriented transmembrane segments. Here, we identified the tail-anchored protein Three p...

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The ER membrane bound DNAse TREX1 prevents your own DNA from becoming viral mimicry. TREX1 can also move around in the cell, but it was unclear how. With collaborators @tudresden.bsky.social we identified TREX1 as a substrate for the intramembrane protease SPP.

link.springer.com/article/10.1...

19.03.2025 17:45 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Collaboration time โ€ฆ now online:

19.03.2025 17:45 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Awsome collaboration with Jonathan Schmid-Burkโ€˜s Lab and other colleagues from @immunosens.bsky.social

19.12.2024 16:53 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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