Thanks @natrevimmunol.bsky.social for highlighting our recent @nature.com paper! @flindersuniversity.bsky.social @sahmri.bsky.social
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Based on these findings we will soon start a randomised controlled trial to determine if a probiotic intervention can boost vaccine responses in infants that received antibiotics in the neonatal period. Funded by
@WCHFoundation
02.04.2025 23:52 β π 0 π 0 π¬ 0 π 0
Very grateful to all our collaborators especially @HelenSMarshall and her team, the infants and their parents who participated in our study, our facilities incl @SA_genomics and the @sahmri.bsky.social
germ-free and flow facilities and our funders @nhmrc.bsky.social and the WCH Foundation
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Neonates who received antibiotics had significantly lower antibody titres to multiple different vaccine antigens especially polysaccharides in the PCV13 vaccine.
02.04.2025 23:52 β π 0 π 0 π¬ 1 π 0
Our paper out today in @nature.com shows the important role Bifidobacteria in the infant gut microbiota play in mediating optimal responses to vaccination.
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Biomedical Scientist π« at the Children's Health and Environment Program, Child Health Research Centre, the University of Queensland.
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Focused on innate immune mechanisms governing pathogenesis of disease and on NK-cell based therapies for disease. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
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