Juan Antonio Rodríguez

We have 🐟 herring pre print!

Our new study reveals that ancient gene flow between Pacific and Atlantic herring played a key role in helping Atlantic herring adapt to the brackish waters of the Baltic Sea.

www.biorxiv.org/content/10.1...

Really grateful to see our work featured by @quantamagazine.bsky.social in this piece on the evolution of genome regulation. Huge thanks to @philipcball.bsky.social for such a beautifully written article.

The variability of goat microRNA genes is strongly shaped by functional constraints Background MicroRNAs (miRNAs) are a type of small non-coding RNAs involved in the post-transcriptional repression of target mRNA transcripts, and responsible for the fine-tuning of numerous molecular ...

Are you interested in microRNAs 🧬 and goats 🐐? We are!!

Then have a look at our preprint on how microRNA mutations segregate worldwide 🌍 in goat populations and the potentially derived consequences of prolonged inbreeding and geographical isolation.

www.biorxiv.org/content/10.1...

You can keep on gatekeeping us small fish, but know that we do good science and we will fight to keep publishing our good science. But also note that your gatekeeping has now cost Anais her whole career. If you're an Editor that did this - you kinda did that dude/dudette.

I particularly liked this.
"To create a true drug discovery engine, he believes we need half a dozen AlphaFold-level breakthroughs."
I mean, we *could* alternatively just do more science - but hell no, let's assume we just need to throw more AI at it.

Symposia - SMBE 2026 - Copenhagen Denmark SMBE 2026 Symposia Check deadlines and important dates below.  Days Hours Minutes Seconds Conference Symposia We are now accepting proposals for symposium for the 2026 Annual meeting taking place in C...

🚨 The #SMBE2026 website is live! 🚨
The call for symposia is now open ➡️ smbe2026.org/symposia/
📅 Opens: Sept 1, 2025
📅 Closes: Oct 15, 2025
📢 Results: Nov 3, 2025
We can’t wait to welcome you to beautiful #Copenhagen 🌍✨
@official-smbe.bsky.social
#evolution #science

Happy to have contributed to this beautiful paper! 🪶

Please repost at #eseb2025 so people will be more careful.

@hologenomics.bsky.social is well represented at this #ESEB2025 week!

Today @hernmoral.bsky.social and @jrotwitguez.bsky.social presented their exciting research!!

#hologenomics

Wonderful wrap up for a great symposium #ESEB2025 - thank you to all parcitipants for their high quality presentations, talks and posters (here most of the female contributors, but there were more 😉)

As the father of the baby, I support this. ✨😁
#ESEB2025

Genome engineering in biodiversity conservation and restoration - Nature Reviews Biodiversity This Perspective argues for the use of genome engineering for restoring species genetic diversity and increase species resilience to environmental change. Genome engineering could be combined with tra...

Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity

How to represent genomes in 3D?

In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅

👉🏼 genomebiology.biomedcentral.com/articles/10....

🚀 En route to #ICCB2025!
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen

if the wheels had come off this thing any faster it'd be a Cybertruck

Por lo menos en los años 20 antes del nazismo y las guerras hubo unas vanguardias, un terremoto cultural del copón bendito.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.

Analysis of Cheddar Man's nuclear DNA indicates that he was a typical member of the Western European hunter-gatherer population at the time, with a most likely phenotype of blue-green eyes, dark brown or black hair, and dark or dark-to-black skin, with no genetic adaption for lactase persistence into adulthood

devastated to discover Cheddar Man was lactose intolerant

Congrats Iana and the team! Super interesting work! 🥳👏

Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...

I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...

Haha… 🍔🦣 the “McMammoth with cheese” is the final goal.

With @hologenomics.bsky.social, we sampled each step of the process to see how microbial communities evolve.

Spoiler alert: Even in a stable, well-behaved system, we found some surprises... 👀 (3/7)

SIBE summer school SIBE SUMMER SCHOOL 2025 7th − 11th September 2025 FERRARA (ITALY) Overview The analysis of genomic data has become increasingly feasible, even in non-model organisms, thanks to the “omics” revolution...

I'll be teaching in the SIBE Summer School in Ferrara, from the 7th to 11th of September.
Great place to learn about PopGen, comparative genomics and ✨Conservation Genomics✨
🚨Deadline to apply: 11th of May🚨
sites.google.com/view/sibesum...

See you there!

April 30, 2025 See you next week at MVIF!  Skin microbiome Large-scale skin metagenomics reveals extensive prevalence, coordination, and functional adaptation of skin microbiome dermotypes across body sites – Che…

New #MicrobiomeDigest: microbiomedigest.com/2025/04/30/a...

•Herrgårds cheese @jrotwitguez.bsky.social‬
•Asian Skin Microbiome Program @cherrychengchenli.bsky.social ‬
•long-read assemblers @floriantrigodet.bsky.social
•argNorm @vedanthramji.bsky.social

CU next week at @microbiomevif.bsky.social!

Inferring past demography and genetic adaptation in Spain using the GCAT cohort - Scientific Reports Scientific Reports - Inferring past demography and genetic adaptation in Spain using the GCAT cohort

I am delighted to share with you some new insights into the selection processes that shaped the Spanish population!

This work has been led by @ebosch1972.bsky.social @francesccalafell.bsky.social ( @upf.edu ) in collaboration with Rafael de Cid ( @igtp.bsky.social ) and @sabiagini.bsky.social

⬇️⬇️⬇️

🎯 Finally, we tried something new: using K-mer counting on raw sequencing reads + Hill numbers to predict microbiome variability across trials.
This could help detect contamination early and stop batches before spoilage. (7/7)

😬 Clostridium tyrobutyricum—the culprit behind “baby vomit” off-flavor (butyric acid)—was completely absent after microfiltration. (The holes in the picture? That’s them.) (6/7)

🦠 We detected two phages whose abundance followed closely with their two host bacteria throughout production. (5/7)

🧫 Milk microfiltration removes almost all non-expected bacteria—good or bad. So only the starter cultures survive and dominate. (4/7)

With @hologenomics.bsky.social, we sampled each step of the process to see how microbial communities evolve.

Spoiler alert: Even in a stable, well-behaved system, we found some surprises... 👀 (3/7)

This was a collab with @novonesis.com aiming to understand how pasteurized milk pretreatments—control, microfiltration, and protein fortification—shape the cheese microbiome during production. (2/7)