Juan Antonio Rodríguez

Genome engineering in biodiversity conservation and restoration - Nature Reviews Biodiversity This Perspective argues for the use of genome engineering for restoring species genetic diversity and increase species resilience to environmental change. Genome engineering could be combined with tra...

Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity

How to represent genomes in 3D?

In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅

👉🏼 genomebiology.biomedcentral.com/articles/10....

🚀 En route to #ICCB2025!
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen

if the wheels had come off this thing any faster it'd be a Cybertruck

Por lo menos en los años 20 antes del nazismo y las guerras hubo unas vanguardias, un terremoto cultural del copón bendito.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.

Analysis of Cheddar Man's nuclear DNA indicates that he was a typical member of the Western European hunter-gatherer population at the time, with a most likely phenotype of blue-green eyes, dark brown or black hair, and dark or dark-to-black skin, with no genetic adaption for lactase persistence into adulthood

devastated to discover Cheddar Man was lactose intolerant

Congrats Iana and the team! Super interesting work! 🥳👏

Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...

I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...

Haha… 🍔🦣 the “McMammoth with cheese” is the final goal.

With @hologenomics.bsky.social, we sampled each step of the process to see how microbial communities evolve.

Spoiler alert: Even in a stable, well-behaved system, we found some surprises... 👀 (3/7)

SIBE summer school SIBE SUMMER SCHOOL 2025 7th − 11th September 2025 FERRARA (ITALY) Overview The analysis of genomic data has become increasingly feasible, even in non-model organisms, thanks to the “omics” revolution...

I'll be teaching in the SIBE Summer School in Ferrara, from the 7th to 11th of September.
Great place to learn about PopGen, comparative genomics and ✨Conservation Genomics✨
🚨Deadline to apply: 11th of May🚨
sites.google.com/view/sibesum...

See you there!

April 30, 2025 See you next week at MVIF!  Skin microbiome Large-scale skin metagenomics reveals extensive prevalence, coordination, and functional adaptation of skin microbiome dermotypes across body sites – Che…

New #MicrobiomeDigest: microbiomedigest.com/2025/04/30/a...

•Herrgårds cheese @jrotwitguez.bsky.social‬
•Asian Skin Microbiome Program @cherrychengchenli.bsky.social ‬
•long-read assemblers @floriantrigodet.bsky.social
•argNorm @vedanthramji.bsky.social

CU next week at @microbiomevif.bsky.social!

Inferring past demography and genetic adaptation in Spain using the GCAT cohort - Scientific Reports Scientific Reports - Inferring past demography and genetic adaptation in Spain using the GCAT cohort

I am delighted to share with you some new insights into the selection processes that shaped the Spanish population!

This work has been led by @ebosch1972.bsky.social @francesccalafell.bsky.social ( @upf.edu ) in collaboration with Rafael de Cid ( @igtp.bsky.social ) and @sabiagini.bsky.social

⬇️⬇️⬇️

🎯 Finally, we tried something new: using K-mer counting on raw sequencing reads + Hill numbers to predict microbiome variability across trials.
This could help detect contamination early and stop batches before spoilage. (7/7)

😬 Clostridium tyrobutyricum—the culprit behind “baby vomit” off-flavor (butyric acid)—was completely absent after microfiltration. (The holes in the picture? That’s them.) (6/7)

🦠 We detected two phages whose abundance followed closely with their two host bacteria throughout production. (5/7)

🧫 Milk microfiltration removes almost all non-expected bacteria—good or bad. So only the starter cultures survive and dominate. (4/7)

With @hologenomics.bsky.social, we sampled each step of the process to see how microbial communities evolve.

Spoiler alert: Even in a stable, well-behaved system, we found some surprises... 👀 (3/7)

This was a collab with @novonesis.com aiming to understand how pasteurized milk pretreatments—control, microfiltration, and protein fortification—shape the cheese microbiome during production. (2/7)

The effect of different milk pretreatment methods on microbiome community development during Herrgårds cheese production and ripening. One of the biggest challenges for dairy producers is the substantial variability in final product properties caused by changes in the production environment. In cheese production, this variation is in...

🧀 New preprint drop: adventures in the cheese microbiome! 📝

We tracked microbiome dynamics across 14 production steps of industrial Herrgårds cheese (Swedish classic 🇸🇪🧐).
www.biorxiv.org/cgi/content/...
(1/7)

Interested in New Frontiers in Genome Diversity and Evolution?

Join us at @eseb2025.bsky.social
in beautiful & sunny Barcelona 🌞

Submit your abstract to Symposium #38

Organized by Thea Rogers (University of Vienna), Rui Faria (Rui M) (University of Porto), and myself (UAB)

👇

🚨 New preprint!
We analyzed 39 bird genomes—including 3 Mauritian species that bounced back from the brink of extinction—to explore genomic erosion in a comparative framework.
🧬🦜🧩
📄 www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social

The orange-bellied parrot is predicted to go extinct by 2038. We tracked >200 years of genomic erosion. Here’s what we found 🧬🦜 #ConservationGenomics #consgen #popgen
onlinelibrary.wiley.com/doi/10.1111/...
pic by Marc Gardner

🧬🌍 Happy to see our latest paper out at @royalsocietypublishing.org
We show how genetic risks in endangered species can stay hidden due to a time-lag between demographic collapse and genetic loss. Work led by amazing MSc students Xufen Liu and Ester Milesi #ConservationGenomics
Pic by David Stowe

Dental calculus, the preserved oral microbiome, is an absolute treasure trove of information that can be interrogated across thousands of years. But how to make it work? In a new preprint, @markella-morait.bsky.social asks this questions using >30 mammalian species:
doi.org/10.1101/2025...

An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write

www.nature.com/articles/s41...

Yeah, like Europe offered a wealth of academic job opportunities and non-precarious working conditions to scientists.

💜Avui celebrem el #8M 💜 acostant la ciència a la gent del barri. Les veïnes de La Barceloneta han vingut a conèixer el CRG i descobrir com investiguem el futur de la biomedicina ben a prop de casa. #DiaDeLaDona #InternationalWomensDay #Diainternacionaldelamujer #LaBarceloneta