Amir Sariaslan

Jag hoppas verkligen att du inte svarade på mailet.

Well played, Michel.

Awesome!

Congratulations!

Its probably nothing, but if it is... A rare copy number variant appears to significantly reduce the risk of schizophrenia.

I wrote about a rare genetic variant (a CNV) that appears to reduce the risk of schizophrenia diagnosis by ~5x, and why that's not as unambigously amazing as it sounds, but potentially still a pretty big deal.

This is bananas.

Well played.

Touché.

AI eller aj - det är frågan.

I got stuck on the first exercise.

How it started
How it’s going

Amazing work from my colleague and postdoc Dr. Isabelle Foote on the genetic architecture of frailty. Encourage you to check it out!!!!

Structural variants are significant contributor to autism. But many SVs & TRs are hard to detect with short reads. Long read sequencing with @pacbio.bsky.social and @nanoporetech.com captures and maps out alot of what short reads miss. So what can LR-WGS tell us about autism? 🧵

Childhood household dysfunction and psychiatric, criminal, and social outcomes in emerging adulthood. A cousin comparison study AbstractBackground. Childhood household dysfunction is a well-known risk factor for adverse medical and social outcomes. However, less is known about the e

Pleased to share our latest paper: academic.oup.com/ije/article/...

Use of real world data to understand self-harm risk in people prescribed gabapentinoids Consider routine follow-up, especially after medication has been stopped Gabapentinoids, including gabapentin and pregabalin, are a class of drugs that have anticonvulsant, analgesic, and anxiolytic ...

NEW EDITORIAL 📢
Seena Fazel and Amir Sariaslan respond to a paper looking at the risk of self-harm in people prescribed gabapentinoids (gabapentin and pregabalin) - a class of drugs which are often used to treat epilepsy and pain disorders Read it in the BMJ: www.bmj.com/content/389/...

Månadens lärdomar: April, 2025 Djupdykning i två norska studier om hur utbildning går i arv mellan föräldrar och barn, samt om svårigheten att tolka förändringar i genomsnittligt IQ bland unga män som genomgår mönstring.

Vad har vi lärt oss om beteendegenetik och psykiatrisk epidemiologi i april?

Jag har sammanfattat ett antal intressanta artiklar. Dela gärna inlägget i era nätverk 🙏🏼

amirsariaslan.substack.com/p/manadens-l...

Månadens lärdomar: Mars, 2025 Genetiska kopplingar mellan adhd, dyslexi och dyskalkyli; könsskillnader i specifika symtom och tecken för adhd; menstruationscykelns betydelse för psykiatri och mer därtill...

Vad har vi lärt oss om beteendegenetik och psykiatrisk epidemiologi i mars?

Jag har sammanfattat ett antal intressanta artiklar. Dela gärna inlägget i era nätverk 🙏🏼

amirsariaslan.substack.com/p/manadens-l...

Our new study in BJPsych, for anyone with an interest in a) bridging the gap to clinical usefulness for prediction tools, and b) thinking more clearly about assessing/doing helpful things to reduce violence risk in clinical services for psychosis. doi.org/10.1192/bjp.... (open access)

Ett nytt mässlingsutbrott i Texas har lett till att 259 barn insjuknat sedan januari. Av dessa var 99,2 % ovaccinerade, inklusive ett barn som avled utan att ha några underliggande sjukdomar.

www.dshs.texas.gov/news-alerts/...

Does nobody have a calculate? Or common sense? Or a olfactory sensor to do a sniff test?
A "new study" finds that 2% of US Adults have been injured at a mass shooting.
No.
"7% reported having been present."
7% of US adults = 18,346,00 people
Are you effing kidding me?

I thought this was some stats sorcery behind my comprehension (CUPED? FWL?) but then I looked it up and…it’s literally just about adjustment for pre-treatment variables?! Why do people keep making up terms 😭 Controlled-experiment Using Pre-Experiment Data, seriously???

"Some people say, 'Oh, you're a hero,' " Harrison told NPR in 2015. "But I'm in a safe room, donating blood. They give me a cup of coffee and something to nibble on. And then I just go on my way. … No problem, no hardship."

mensch

Tack Johan!

Stort tack för detta! Kul att du uppskattade inlägget.

Månadens lärdomar: Februari, 2025 Vad visade den nya kanadensiska studien om cannabis och schizofreni egentligen? Även: Oklara effekter av mobilförbud i brittiska skolor samt mer miljö än arv bakom tatueringar i Danmark.

Vad har vi lärt oss om beteendegenetik och psykiatrisk epidemiologi i februari? Jag har sammanfattat litteraturen: amirsariaslan.substack.com/p/manadens-l...

Dela gärna inlägget i era nätverk 🙏🏼

So long, betalvägg! Nu försvinner betalväggen från nyhetsbrevet. Samtliga inlägg kan numera läsas helt kostnadsfritt.

I dagens inlägg förklarar jag bakgrunden till mitt beslut att ta bort betalväggen i mitt nyhetsbrev "Arv, miljö och slump". Du kan läsa inlägget här: amirsariaslan.substack.com/p/so-long-be...

Huge congratulations!

Rolf is a European treasure.

You have to be Swedish to understand this one.