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Satyaki PRV

@satyakirv.bsky.social

Assistant Professor, University of Toronto Scarborough. Genetics, plant development, epigenetics, climate change, science fiction and history. https://www.satyaki-lab.com/ https://scholar.google.com/citations?user=tPfWn1MAAAAJ&hl=en

412 Followers  |  953 Following  |  77 Posts  |  Joined: 10.09.2023  |  2.0827

Latest posts by satyakirv.bsky.social on Bluesky

One thing I definitely miss about Amreeka. Happy Thanksgiving!

27.11.2025 22:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Probably a demethylase target.

22.11.2025 16:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Coconut endosperm? :D

08.11.2025 17:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The Control of Arabidopsis thaliana Growth by Cell Proliferation and Endoreplication Requires the F-Box Protein FBL17 - PubMed share.google/kfYf22LoZ3RH...

Also, e2f and del mutants might have a similar phenotype.

08.11.2025 14:07 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

For 61 years the #BBCWorldService has been broadcasting the latest in science via its weekly Science in Action programme. That dies in the next half hour, with this final edition, reflecting on the fall in trust in expertise driven by malign interests over recent years.

30.10.2025 20:20 β€” πŸ‘ 305    πŸ” 198    πŸ’¬ 25    πŸ“Œ 25
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Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites - Nature A recombinant antivenom composed of eight nanobodies provides broad protection against venom-induced lethality and dermonecrosis in mice challenged with venoms from cobras, mambas and rinkha...

Snake bites kill/debilitate 1000s of people annually in Sub-Saharan African. A new nanobody cocktail is shown to be highly effective against 17 of the most dangerous African snake species. Unlike other anti-venoms it also protects against venom-induced dermal necrosisπŸ§ͺ
www.nature.com/articles/s41...

30.10.2025 07:26 β€” πŸ‘ 47    πŸ” 15    πŸ’¬ 0    πŸ“Œ 0

Transposable elements drive much of naturally occurring genetic lethality in Drosophila melanogaster https://www.biorxiv.org/content/10.1101/2025.10.16.682755v1

16.10.2025 19:32 β€” πŸ‘ 25    πŸ” 14    πŸ’¬ 0    πŸ“Œ 1
Client Challenge

genomebiology.biomedcentral.com/articles/10....
From the Gehring Lab.

Ros1 prevents paternal hypermethylation of the endosperm genome.

13.10.2025 15:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Inhibition of DCL4 activity by maternally supplied flavonoid aglycons induces a bicolor pattern in the saddle soybean seed coat A model showing a proposed molecular mechanism for the bicolored pattern formation in the saddle soybean seed coat. The spatial feedforward regulation consisting of DCL4 and flavonoid aglycons includ...

onlinelibrary.wiley.com/doi/10.1111/...

Cool observation.

12.10.2025 14:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Lab’s 1st preprint!

Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.

@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.

He is on the job market!

10.10.2025 13:26 β€” πŸ‘ 299    πŸ” 90    πŸ’¬ 18    πŸ“Œ 8
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Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.

05.10.2025 09:08 β€” πŸ‘ 38264    πŸ” 17087    πŸ’¬ 822    πŸ“Œ 2410
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Nobelist George Smoot, whose satellite experiments validated the Big Bang theory, dies at 80 - Berkeley News Smoot, a physicist at UC Berkeley and Berkeley Lab, shared the 2006 Nobel Prize in Physics for detecting minute temperature variations in the cosmic microwave background, a prediction of the Big Bang ...

Aww man, Smoot died.

One of my dad's small points of pride that he handed a very special bottle of photoresist under the table as "test sample" to a pair of researchers who were never gonna order industrial quantities, but was enough to make COBE's detectors. news.berkeley.edu/2025/09/29/n...?

30.09.2025 22:39 β€” πŸ‘ 180    πŸ” 42    πŸ’¬ 4    πŸ“Œ 0

Just an outrageous amount of structural variation in pennycress. While not yet reproductively isolated, its likely these shredded pericentromeres contribute to some reproductive incompatibilities.

29.09.2025 17:33 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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The dawn of the post-literate society And the end of civilisation
28.09.2025 23:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congratulations!!

25.09.2025 19:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Out today in JAERE! We measure water pollution released at India's industrial clusters. Does it hurt agriculture? Surprisingly: Not by much

Come for how we published a paper of null results & with no regression tables

Stay for new ways to proxy for crop yields & map hydrological relationships

🧡

19.09.2025 20:28 β€” πŸ‘ 16    πŸ” 9    πŸ’¬ 2    πŸ“Œ 0
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A single-cell rice atlas integrates multi-species data to reveal cis-regulatory evolution - Nature Plants This study maps chromatin accessibility at single-cell resolution in rice and related grasses, revealing how regulatory DNA elements evolve across cell types and species and identifying potential sile...

Some more cool single-cell powered gene regulatory atlases from the Schmitz lab.

20.09.2025 11:42 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Rapid emergence of non-autonomous elements may stop P-element invasions in the absence of a piRNA-based host defence Author summary Transposable elements (TEs) are short, self-replicating DNA sequences found in nearly all genomes. While they can be harmful to their hosts, many organisms have evolved defence systems,...

Germline defence from TEs largely relies on piRNAs. Yet, @divyaselvaraju.bsky.social and I monitored a P-element invasion in Drosophila that was stopped by an internally deleted copy, no host intervention required!
doi.org/10.1371/jour...
Many thanks to @rpianezza.bsky.social & @rokofler.bsky.social

28.08.2025 13:27 β€” πŸ‘ 31    πŸ” 18    πŸ’¬ 2    πŸ“Œ 2
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Is this the future of food? 'Sexless' seeds that could transform farming Scientists are tinkering with plant genes to create crops that seed their own clones, with a host of benefits for farmers.

Nature reports on the development of β€œsexless seeds,” which are crops that seed their own clones and have a host of benefits for farmers. #plantscience πŸ§ͺ

06.09.2025 16:05 β€” πŸ‘ 19    πŸ” 7    πŸ’¬ 1    πŸ“Œ 4
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University closures and declining regional innovation: evidence from South Korea Abstract. This paper empirically examines the impact of university closures on local innovation in South Korea from 2011 to 2021, against the backdrop of d

This is a very cool article on a deeply under-researched topic.

06.09.2025 15:17 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Plant cells are totipotent, meaning individual cells have the potential to develop into a full organism, a property unique to the zygote for animals. However, in most species for most cells, plant cells are not spontaneously totipotent, since they must be treated with specific hormone combinations to unlock their totipotency. Species within the Kalanchoe genus is unique as they spontaneously develop foliar embryos that are fully realized plantlets with shoot and root from notches along the edges of leaves. We speculate that the progenitor cells that give rise to these foliar embryos are totipotent, and we are using single cell techniques to identify & characterize them. In addition to being a fundamental process for plant biology, we foresee unlocking totipotency has many biotechnological applications, such as faciliating genetic transformation and the development of synthetic organs of biomanufacturing.

Please share! I'm looking for a postdoc. The position is to lead one of the following projects: 1) regulation of plant specialized metabolism by cell fate, or 2) foliar embryogenesis in the succulent plant Kalanchoe.

Learn more abt projects: cxli233.github.io/cxLi_lab/res...

04.09.2025 14:00 β€” πŸ‘ 88    πŸ” 110    πŸ’¬ 1    πŸ“Œ 3
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Inactivation of Ξ²-1,3-glucan synthase-like 5 confers broad-spectrum resistance to Plasmodiophora brassicae pathotypes in cruciferous plants - Nature Genetics This study implicates GSL5 inactivation in high, broad-spectrum resistance to the clubroot pathogen Plasmodiophora brassicae in Arabidopsis thaliana, Brassica napus, Brassica oleracea and Brassica rap...

Inactivation of Ξ²-1,3-glucan synthase-like 5 confers broad-spectrum resistance to Plasmodiophora brassicae pathotypes in cruciferous plants
www.nature.com/articles/s41...

01.09.2025 10:06 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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Transgenerational decline through insidious effects of drought memory Click on the article title to read more.

nph.onlinelibrary.wiley.com/doi/10.1111/...

31.08.2025 05:01 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A species-wide inventory of receptor-like kinases in Arabidopsis thaliana

Thrilled to announce our new paper is now out in @bmc.springernature.com

rdcu.be/eCB2t

27.08.2025 15:31 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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In Other Journals Editors’ selections from the current scientific literature

My pick for In Other Journals this week:
MSH1 suppresses organelle mutation - an investigation of how many plants maintain very low mitochondrial mutation rates

My summary here:
www.science.org/doi/10.1126/...

Paper here: doi.org/10.1371/jour...
@sloanevolab.bsky.social
#PlantScience

22.08.2025 08:40 β€” πŸ‘ 17    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Emerging evidence of abrupt changes in the Antarctic environment - Nature Abrupt changes are developing across Antarctica’s ice, ocean and biological systems; some of these changes are intensifying faster than equivalent Arctic changes, potentially irreversibly, and their i...

www.nature.com/articles/s41...

21.08.2025 02:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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How can England possibly be running out of water? While famously rainswept, climate crisis, population growth and profligacy mean the once unthinkable could be possible

How can England possibly be running out of water?

www.theguardian.com/news/ng-inte...

17.08.2025 08:14 β€” πŸ‘ 34    πŸ” 15    πŸ’¬ 2    πŸ“Œ 2
Our current carbon economy relies on fossil fuels, from which we isolate small organic molecules to produce medicines, plastics, cosmetic, or other chemicals that we use everyday. However, sustainability requires a more biomass-based carbon economy, where we engineer plants to produce precursor molecules, which can then be assembled to desired chemicals that we use daily. Plants have evolved an amazing diversity of metabolites, but these metabolites are not produced in every cell of the plant. Therefore, it is essential to understand how plants can express different metabolic pathways across different organs, tissues, and even cell types. We are interested in the following questions: How are metabolic pathways (especially specialized metabolism) controlled by cell fate? How can we reprogram plant cell fates for biomanufacturing? How can we toggle between differentiated cell states for metabolic engineering and totipotent cell state for genetic engineering?

Last week I requested a tech and a postdoc position to be created and submitted the ads for those positions. Stay tuned for the official ad. For inquiries, my contact can be found here: cxli233.github.io/cxLi_lab/

14.08.2025 20:24 β€” πŸ‘ 19    πŸ” 14    πŸ’¬ 0    πŸ“Œ 0

A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.

www.philanthropy.cam.ac.uk/give-to-camb...

14.08.2025 05:25 β€” πŸ‘ 80    πŸ” 111    πŸ’¬ 1    πŸ“Œ 5

What’s your favorite food fact that is true but sounds totally made up?

I’ll start: about half of the mushrooms produced across the United States of America each year (more than 300 million pounds of mushrooms in recent years) are produced in *one county* in Pennsylvania.

09.08.2025 18:22 β€” πŸ‘ 1558    πŸ” 202    πŸ’¬ 202    πŸ“Œ 289

@satyakirv is following 20 prominent accounts