Evangelia Petsalaki

Evangelia Petsalaki

@epetsalaki.bsky.social

Group Leader at EMBL-EBI. Our group uses interdisciplinary approaches including network analysis, omics integration and mathematical modelling to study the context specific regulation of human cell signalling.

451 Followers 236 Following 69 Posts Joined Nov 2024
10 hours ago
The Critical Assessment of Structure Prediction (CASP) experiment is calling for prediction targets: Immune Complexes, Organic Ligand-Protein Complexes, Nucleic Acids and Complexes, Conformational Ensembles, Difficult Protein Structures and Complexes. 
Rule of Thumb: If AlphaFold3 can generate a high-quality model, it is likely not a CASP-grade challenge. If it struggles, we want it.

Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬

Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes.

The Rule of Thumb: If AF3 can’t model it, we want it.

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2 days ago
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We’re recruiting new Research Group Leaders!
Why join?
🌍Work across EMBL’s 6 sites
🎓Participate in @embl.org courses and seminars
🔬Lead discovery-driven research in a collaborative environment
Apply by 11 April: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ResearchCareers @epetsalaki.bsky.social

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1 week ago

Thank you very much for hosting me!

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1 week ago

Thank you!

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1 week ago

Our preprint is published in MSB! This time with the correct preprint post below! link.springer.com/article/10.1...

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1 week ago

I realise I reposted the wrong bioRxiv! will amend later

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2 weeks ago
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This #RareDiseaseDay, we’re highlighting how open data sharing supports diagnosis, research, and families living with rare conditions.

Watch to find out how access to rare disease data through @deciphergenomics.bsky.social can help families better understand their children’s rare conditions.

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2 weeks ago
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FEBS Press Held on 20 November 2025 at Human Technopole in Milan, the 2nd European Cancer Dependency Map Symposium convened experimental and computational scientists to discuss how cancer dependency mapping in ...

Our thoughts, impressions, and presentations of the "2nd EuroDepMap symposium" in Milan (Nov 2025) are online at
@febsletters.bsky.social.

febs.onlinelibrary.wiley.com/doi/10.1002/...

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3 weeks ago

Our preprint is now published in MSB. link.springer.com/article/10.1...
We decompose multi-omics into distinct phenotypic axes (drug response vs ARID1A-driven cell state), improving interpretation and revealing how baseline cell state rewires signaling and shapes MAPK inhibitor resistance.

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3 weeks ago

Do you want to pursue your ideas in computational biology independently, running your group in @embl.org‘s uniquely collaborative environment, beside world’s most comprehensive biomolecular data resources @ebi.embl.org in Genome Campus next to @sangerinstitute.bsky.social?
Apply to join us & share 🙏

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3 weeks ago
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📢 This Week at #IRBBarcelona: Join us for a plenary #seminar this Friday, with Dr. @isidrolauscher.bsky.social from @ebi.embl.org @sangerinstitute.bsky.social @cancerresearchuk.org 

🤝 Hosted by @nlbigas.bsky.social and @milanlab.bsky.social 

Register here ➡️ https://shorturl.at/imwHx

🧪

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1 month ago
Bioinformatician/Senior Bioinformatician Functional Genomics Research Centre Bioinformatician/Senior Bioinformatician Functional Genomics Research Centre

Looking for bioinformatician for exciting projects across the Centre of Genomics at the Human Technople. We also work with the FANTOM6 Consortium and other international consortia/projects. Details below:

careers.humantechnopole.it/job/Bioinfor...

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1 month ago
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Rewiring of oncogenic signaling in #DrugResistance is a moving target. In our new study, we used biophysical phosphoproteomics to investigate #BRAF mutant cancer, linking phosphorylation changes to protein function and #MolecularMechanisms through #Multi-Omics integration.
tinyurl.com/funsignaling

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1 month ago
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We’re hiring: Research Group Leader in computational biology.

Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI.

Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

#ScienceCareers @ewaldlab.org @embl.org

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1 month ago
Person standing outside next to a building wearing a red jacket

Meet Leonie Johanna Lorenz 🇩🇪, a Predoctoral Fellow at EMBL-EBI who is bringing mathematical modelling to microbes.

Find out more about how Leonie’s passion for modelling patterns extends from bacterial evolution to sewing 🧵

www.ebi.ac.uk/about/news/p...

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1 month ago

Indeed an amazing place to start your group! Don't miss the opportunity!

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1 month ago
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Pervanadate-induced oxidation relieves autoinhibition of the protein tyrosine kinase SRC A widely used tyrosine phosphatase inhibitor also oxidizes and activates the tyrosine kinase SRC.

Pervanadate is more than just a phosphatase inhibitor!

Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.

Link: tinyurl.com/5ype7e2s

Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3

@babrahaminst.bsky.social

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1 month ago
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EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.

We extend our deepest condolences to his family, friends, and colleagues.

www.embl.org/news/people-...

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1 month ago

Truly shocked and saddened by the loss of this brilliant man, scientist and mentor.

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2 months ago
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On this day in 2021, I landed in a snowy, lockdown-silenced Heidelberg to start my lab. 5 years later we are a force to reckon with in our field, and the first generation are striking out on their own. I couldn’t be more proud, & grateful to them and our wonderful collaborators around the world 🌍 🧪

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2 months ago
Group Leader - Generative Biology and AI Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

Looking to start your lab in generative biology / AI?
Come join us at the @sangerinstitute.bsky.social
Sanger is core-funded so you can generate data at scale to train the next generation of models and understanding. Design/Engineering/Chemistry/Proteins/Pathways!
pls RT
tinyurl.com/GenGenFaculty

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2 months ago
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CeMM PhD Program – Molecular Medicine Research in Vienna Join the CeMM PhD Program in Vienna and pursue cutting-edge research in cancer, immunology, aging, and precision medicine. Applications open in 2025!

HIRING: We recruit PhD students via the AITHYRA-CeMM PhD Program (cemm.at/phd-program). Seeking 3 types of candidates: (1) experimental systems biology in immunity or cancer; (2) bioinformatics & biomedical ML/AI; (3) tech-dev & bioengineering (CRISPR, single-cell, spatial, cell programming) (1/5)

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2 months ago

1/ We’re hiring PIs in AI × Biology
The @astar-gis.bsky.social Genome Institute of Singapore (GIS) is expanding its AI & Computation domain and recruiting junior & senior PIs.

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3 months ago
Boehringer Ingelheim hiring Senior or Principal Scientist of Human Genetics in Biberach an der Riß, Baden-Württemberg, Germany | LinkedIn Posted 3:27:12 PM. The PositionAbout us: Computational Innovation @ Boehringer Ingelheim…See this and similar jobs on LinkedIn.

Our Human Genetics team @boehringerglobal.bsky.social (Biberach site, Germany) is actively searching for an experienced Statistical Geneticist.

#StatisticalGenetics #HumanGenetics #BoehringerIngelheim #ComputationalInnovation #JobOpportunity

lnkd.in/g6QPihVE

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3 months ago

From @irbbarcelona.org #ICREAResearcher Patrick Aloy @ptck72.bsky.social has taken part in a study published in @nature.com that broadens the possibilities for designing more effective drug therapies 👇

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3 months ago

Exciting collaboration with @saezlab.bsky.social @ebi.embl.org Tamas Korcsmaros @imperialcollegeldn.bsky.social and @opentargets.org

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3 months ago
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Postdoctoral fellow - Petsalaki Group - NetworkCommons Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...

#Postdoc alert! We are looking for motivated individual with experience in computational systems biology to join our NetworkCommons initiative to benchmark and democratise network contextualisation methods across multiple applications. Deadline Dec 17th link here: tinyurl.com/yrrzxa94

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3 months ago
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Postdoctoral fellow - Petsalaki Group - NetworkCommons Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...

NEW: Postdoc with @epetsalaki.bsky.social @juliosaezrod.bsky.social and Tamas Korcsmáros

Benchmark and integrate state-of-the-art network contextualisation methods, combining large-scale transcriptomics, proteomics, and single-cell data

Apply by 17 Dec

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

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3 months ago
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POSTDOCTORAL FELLOW - Toronto (City), Ontario (CA) job with Taipale Lab, Donnelly Centre, University of Toronto | 12849004 The Taipale lab in the Donnelly CCBR and University of Toronto is looking for a highly motivated Postdoctoral Fellow

We are looking for a postdoctoral fellow to work on induced proximity 🤜🤛 and functional genomics! Join our team in Toronto 🇨🇦 to tackle major challenges in oncology and neurodegeneration. www.nature.com/naturecareer...

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3 months ago
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Applications closing soon for our internship programme aimed at Master's students at French universities 🇫🇷

Are you studying bioinformatics, computer science or statistics? Check it out!

Deadline: 7 December 2025

www.ebi.ac.uk/about/jobs/i...

A collaboration with the French Embassy in London.

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