@pavitrarc.bsky.social
Bioinformatics, viral evolution, math models | UW / Fred Hutch | Loves science, gizmos, silly jokes, dogs | ๐ฎ๐ณโ๐ณ๐ฌโ๐ฌ๐ญโ๐ธ๐ฌโ๐บ๐ธ
Helen Chu is one of the ousted #ACIP members. She spoke to me today about her grave concerns for future vaccination policy and vaccine access in the United States. www.statnews.com/2025/06/10/c...
11.06.2025 01:32 โ ๐ 1250 ๐ 545 ๐ฌ 22 ๐ 27Amazing! Congrats!
24.05.2025 15:41 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0Absolutely thrilled to announce the launch of ARTIC2 - a ยฃ5.5M 5 year project funded by @wellcometrust.bsky.social to build on the ARTIC approach of low-cost, globally accessible genome sequencing for surveillance of outbreaks, epidemics and endemic diseases: www.birmingham.ac.uk/news/2025/am...
22.05.2025 10:57 โ ๐ 227 ๐ 80 ๐ฌ 7 ๐ 4Cover of Emerging Infectious Diseases journal. https://wwwnc.cdc.gov/eid/articles/issue/31/13/table-of-contents
The May 2025 supplemental issue of Emerging Infectious Diseases journal is now live: โAdvances in Pathogen Genomics for Infectious Disease Surveillance, Control, and Prevention.โ
wwwnc.cdc.gov/eid/articles...
1/ How has H5N1 affected this yearโs flu season in Seattle? Despite ongoing outbreaks in birds & cattle nationally, we detected zero H5N1 cases in 675 influenza A-positive specimens tested at UW Medicine.
19.03.2025 14:20 โ ๐ 7 ๐ 2 ๐ฌ 6 ๐ 16/ Read more in our manuscript from the
Greninger Lab
at UW Virology
: medrxiv.org/cgi/content/.... Many people contributed to this work, including
@margaretgracemills.bsky.social, Ailyn Perez-Osorio, and
@pavitrarc.bsky.social.
Iโm so tired of hearing Rubio & other rightwingers now claiming that if youโre on a green card youโre a โguestโ in this country. BS. Youโre a lawful permanent resident. The clue is in the name. If someone is a permanent resident in your home, are they the same as the guests who come and go? Come on.
16.03.2025 15:26 โ ๐ 27541 ๐ 5616 ๐ฌ 790 ๐ 185Grateful to my amazing colleagues and coauthors for contributing to this work. And our collaborators across the pond who generously shared early versions of the ARTIC primers. /end
28.01.2025 19:05 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0tl;dr The assay shows robust performance across a range of viral loads allowing sensitive recovery for RSV genomes from clinical specimens. Its sensitivity makes it suitable for use in clinical trials of antivirals and vaccines allowing early detection of treatment emergent/resistance mutation. 4/
28.01.2025 19:05 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0We determined assay sensitivity, specificity, repeatability and reproducibility; and comparison with Sanger, shotgun, and capture-based sequencing methods to check for accurate recovery of the F gene. We also used contrived samples to determine the LOD of minor variants in allelic mixtures. 3/
28.01.2025 19:05 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0We modified 2 ARTIC primers based on initial tests with samples from USA (WA state), but changes are likely improve performance in global isolates based on current variation at those sites. We were able to recover high quality genomes from clinical samples with a wide range of Cts (95% LOD Ct 30) 2/
28.01.2025 19:05 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0Happy to share our latest preprint describing clinical assay validation for RSV whole genome sequencing using a modified version of the ARTIC RSV panel doi.org/10.1101/2025... <thread> 1/
28.01.2025 19:05 โ ๐ 4 ๐ 1 ๐ฌ 1 ๐ 0Excited to be involved in this study led by Helen Chu as part of the CDC's CHARM network tracking the spread of respiratory viruses across the US.
10.01.2025 05:09 โ ๐ 2 ๐ 2 ๐ฌ 0 ๐ 0My brain as soon as it saw this pop up on my feed: "In the shuffling madness of the locomotive breath" ๐
My dad introduced us to Jethro Tull, listening to these on audio cassettes in the car. Love every single song.
A group of school children sit in front of an orange truck which is a plow/sander. They are holding up a hand-drawn sign which I can't read but I think it says THANK YOU
New names for Vermont snow plows 2024, selected by Vermont schoolchildren. Some selections...
Skibidi Scooper
No More Mr. Ice Guy
The Snowy Pl-Owl
Clearopathra
Snoah Kahan
Salt-O-Saurus
vtrans.vermont.gov/name-a-plow
I think you probably meant this Evan Newell--I don't think he's on bsky.
www.fredhutch.org/en/faculty-l...