Nico Posnien

Excited to share the latest work from the lab:
rdcu.be/eRWuD

Great team effort, led by @enriberti.bsky.social first at @unil.bsky.social and now @unifr.bsky.social; with fantastic collaborators @ribeirocarlitos.bsky.social and @dahaniel.muench.bio.

📢 Job alert: Post-Doc Position in the project "Functional annotation of genomic🧬 innovations in a densely populated clade🪰 with deep learning 💻" Join the GEvol community in a collaborative project between @bornberglab.bsky.social and @katharinahoff.bsky.social lab.
👉 bornberglab.org/post-doc-pos...

PhD position available for theoretical and statistical modeling in my joint @gevol.bsky.social project with @luisapallares.bsky.social on the evolution of transcriptional variability and its role in adaptation and evolutionary innovation.
See
job-portal.lmu.de/jobposting/6...

***Super cool-project alert***⚠️ Come work with @dirkmetzler.bsky.social and me in trying to understand how transcriptional noise evolves in a phylogenetic context 🧬 Deadline 15th Dec 2025 (Project funded by @dfg.de @gevol.bsky.social)

Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp

Detail from Figure 1 of the linked preprint: a diagram contrasting the two weasel morphs, one of which is brown in summer and white in winter, and the other of which is brown all year; with images of weasels in both forms of winter coat; and then nucleotide and amino acid sequences for the two MC1R variants underlying the two coat types

These weasels have locally adapted their winter coats to varying snow cover thanks to a million-year-old mutation 🌿

buff.ly/TnOfYWt

Thanks for the suggestion! Will do!

🏫Comprehensive training program: www.uni-goettingen.de/de/training/...
📍 Location: Göttingen, Germany
📆Deadline: January 14, 2026
❓Inquiries: pm me.
Ready to dive into an exciting #EvoDevo project? Apply via the link below! 👇
www.uni-goettingen.de/de/556704.html

🧬 The Project: You will identify the Gene Regulatory Networks (GRNs) driving head horn development by comparing "horn" vs. "no-horn" phenotypes.
🛠️ Methods:
developmental single-cell omics, RNAi & HCR imaging
🎓 You: MSc in DevBio, Genetics, or EvoBio. Experience with sc-sequencing is a ➕!

📢 PhD Position Alert! 🪲
Fully funded PhD position (65% TV-L E13) at @uni-goettingen.de to study the evolution of morphological novelties in a darkling beetle.
You will join the interdisciplinary "GönomiX" graduate school: www.uni-goettingen.de/de/home/6242...

Individual projects are available in the following groups: @bucherlab.bsky.social, @mtaguado.bsky.social, @mariekeoudelaar.bsky.social, Jochen Rink, Tim Beissbarth, Anne-Christin Hauschild, @posnienlab.bsky.social, Daniel Jackson, @plenart.bsky.social.

🎓Includes a structured training program, retreats, and workshops: www.uni-goettingen.de/de/training/...
Interested? 🗣️ Online Q&A: Dec 17th, 2pm CET (Zoom) 📅 Application deadline: Jan 14th, 2026
📝Apply via the joint portal with @imprsgs.bsky.social: www.uni-goettingen.de/de/applicati...

🤝 Join a collaborative team of 9 PIs from @uni-goettingen.de & @mpi-nat.bsky.social
You will either: 💻 Pioneer novel bioinformatics tools, or 🧪 develop tools to study gene function (Genome editing, single-molecule imaging)
Project details: www.uni-goettingen.de/de/research/...

🧬 10 @dfg.de-funded PhD positions at @goettingen-campus.de 🧬
❗Focus: Evolution of gene regulatory networks & Wnt signaling in emerging models (insects, snails, flatworms, cnidarians).
💻 Methods: 'Omics, Bioinformatics, CRISPR/RNAi & Imaging.
📌Start: June 2026.
#EvoDevo #Genomics #Bioinformatics

This entire project is a multi-lab collaboration with @nturetz.bsky.social y.social, @mcordellier.bsky.social dellier.bsky.social, @pechmannm.bsky.social mannm.bsky.social & Niko Prpic-Schäper

🛠️ Ideally, you bring: Bioinformatic skills in comparative genomics, orthology, RNAseq, phylogenomics, or genome assembly.
📅 Deadline: January 14, 2026 📧 Inquiries: pm me.
Apply here & please repost! 🔄 www.uni-goettingen.de/de/556704.html

💻 The Project: We will integrate multi-omics (bulk/scRNAseq, long-reads, ATAC-seq) to explore how duplicated genes diverge in regulation and function.
🤝 You will be part of the DFG SPP 2349 @gevol.bsky.social consortium & the @imprsgs.bsky.social, with research visits to collaboration partners (👇).

🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics

Guns n Roses: Knocking on heavens door
Limp Bizkit: Faith
Marilyn Manson: Sweet dreams
(the latter despite dropping support for this guy for obvious reasons, but the interpretation of this horrible 80's song is soooo good)

Big news last week, our project within @gevol.bsky.social got funded! 🤩 @nturetz.bsky.social @pechmannm.bsky.social @posnienlab.bsky.social, Niko Prpic-Schäper and myself will look into molecular mechanisms and phenotypic consequences of paralog divergence in insects and chelicerates. Stay tuned!

Whoop! Congrats! Have a great start over there!

#Drosophila rules! Help us spread the word @drosospain.bsky.social @fly-eds.bsky.social @genetics-gsa.bsky.social @sse-evolution.bsky.social @fly-jedi.bsky.social @flybase.bsky.social @alliancegenome.bsky.social

To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)

GitHub - esradm/DrosEU_PhenotypingWG Contribute to esradm/DrosEU_PhenotypingWG development by creating an account on GitHub.

All the data is available in @github.com (6/7)
github.com/esradm/DrosE...

Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster Abstract. A particularly well-studied evolutionary model is the vinegar fly Drosophila melanogaster, a cosmopolitan insect of ancestral southern-central Af

Phenotypic divergence among European populations was assayed in 173 isofemale lines, spearheaded by Esra Durmaz Mitchell and Thomas Flatt, we show that populations differed markedly in multivariate trait structure @evolletters.bsky.social @eseb.bsky.social academic.oup.com/evlett/artic... (5/7)

This community effort includes sampling by high school students part of the #citizenscience project #MelanogasterCTF, a joint project between @gonzalezlabbcn.bsky.social and @lcatmon.bsky.social in collaboration with Sònia Casillas @uab.cat, @droseu.bsky.social and #FECYT melanogaster.eu (4/7)

Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource Abstract. Large-scale genomic resources can place genetic variation into an ecologically informed context. To advance our understanding of the population g

DESTv2 analyses show that the spatial genetic structure of populations is stable over time; identify signatures of adaptation that vary between continents; and provide new evidence for seasonal adaptation @molbioevol.bsky.social @official-smbe.bsky.social : academic.oup.com/mbe/article/... (3/7)

An expanded release of the community-generated population genomics resource DEST, spearheaded by Marta Coronado-Zamora @geneticament.bsky.social and Joaquin Nunez @jcbnunez.bsky.social, is now available at dest.bio (2/7)

We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)

Cell movements around the organizer/node after stage HH4.

Fate maps of the ectodermal (dorsal) layer of the organizer/node, based on Selleck and Stern (1991) (Selleck and Stern, 1991).

Cell movements of populations contributing to the organizer.

Stages of early chick development referred to in the text. The diagrams show some of the features used to classify the stages in relation to primitive streak formation.

We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...