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Ian Copple

@iancopple.bsky.social

MRC Senior Fellow, Professor of Pharmacology & Toxicology, University of Liverpool. Leading the Stress Response Lab (www.liverpool.ac.uk/stress-response-lab) and Human Liver Research Facility (www.liverpool.ac.uk/hlrf).

561 Followers  |  578 Following  |  37 Posts  |  Joined: 15.11.2024  |  1.6457

Latest posts by iancopple.bsky.social on Bluesky

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(BBSRC NWD CASE) Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities at University of Liverpool on FindAPhD.com PhD Project - (BBSRC NWD CASE) Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities at University of Liverpool, listed on FindAPhD...

πŸ“’ Fully funded PhD opportunity in my group!

Project title: Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities.

Application deadline: 7 December 2025.

Details/apply: tinyurl.com/2jcp9jfz

Questions: Get in touch!

11.11.2025 21:37 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Earlier this month I had a fantastic time in Galway, Ireland attending the SFRRI biennial meeting and the @benbedphar.bsky.social satellite meeting. Nice to catch up with friends and colleagues, including the 'Godfather' of the NRF2 field Masi Yamamoto!

19.06.2025 12:29 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Outstanding talk by @parikki.bsky.social , recipient of the CATHERINE PASQUIER AWARD LECTURE at SFFR-I Biennial Meeting in Galway @uniofgalway.bsky.social.

Are ROS generated in nanodomains / condensates in cells?

Want to know more, please read her paper
lnkd.in/dq_6Rnaw

@sfrre-ecr.bsky.social

06.06.2025 11:11 β€” πŸ‘ 12    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Liverpool's @parikki.bsky.social giving the Catherine Pasquier Award lecture at the SFRRI Biennial Meeting in Galway. Fantastic talk πŸ‘πŸ»

@liverpooluni.bsky.social @livuni-ismib.bsky.social
@livunihls.bsky.social

06.06.2025 10:07 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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A huge well done to group member Hannah Coghlan for passing her PhD viva today. It's been a pleasure to work with Hannah over the past 4 years, she deserves all of her success. Congratulations Dr Coghlan πŸΎπŸŽ‰πŸ‘πŸ»

13.05.2025 13:42 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Big congratulations to group member Hannah Coghlan for winning a poster prize at the British Toxicology Society annual meeting. Very well done πŸ‘πŸ»

09.05.2025 13:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Fantastic presentation from group member Olivia Harris as part of the selected oral communications session at the British Toxicology Society annual congress.

08.05.2025 14:01 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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After months of preparation, we're finally ready to kick off the British Toxicology Society annual congress in Liverpool. Thanks to the rest of the organising committee for making this possible. Looking forward to a great meeting!

07.05.2025 09:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

Yes great meeting. I had to leave but still have the pen you kindly lent me for the poster judging. I'll return it next Monday!

24.03.2025 14:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Coming to the end of a fantastic few days in Rome participating in the @benbedphar.bsky.social meeting at Sapienza University. Great discussions about progress and next steps for NRF2 pharmacology. Managed to squeeze in a Parkrun too! πŸƒπŸ»β€β™‚οΈ

22.02.2025 10:17 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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New Centre for Excellence in Regulatory Science and Innovation in #Pharmacogenomics to help UK move towards personalised prescribing:

news.liverpool.ac.uk/2025/01/28/n...

@livunihls.bsky.social @livuni-ismib.bsky.social @innovateuk.bsky.social @ukri.org

28.01.2025 12:00 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Please add me Antonio

19.01.2025 12:27 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Nice to catch up as a group over lunch. Some great restaurant deals in January πŸ˜„

17.01.2025 14:01 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Carers in STEMM: Caring Responsibilities Are you a UK-based academic or student balancing your role as a caregiver with your research? We want to hear your lived experiences!

Are you a parent? Or caring for another adult, relative, friend? And are you a UK-based #academic? πŸ§ͺ
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues

15.01.2025 10:19 β€” πŸ‘ 3    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
"Dates for your diary 2025" and the British Pharmacological Logo on a faux-leather background with stationary and a sticker.

"Dates for your diary 2025" and the British Pharmacological Logo on a faux-leather background with stationary and a sticker.

✨ Happy New Year! ✨ We hope your 2025 has got off to a fantastic start! To help you plan for the year ahead, we've compiled some key dates for your diary: www.bps.ac.uk/news/article... πŸ§ͺπŸ’ŠπŸ—“

#Pharmacology #ClinicalPharmacology #Pharmacogenomics #STEM #STEMEvents

09.01.2025 16:27 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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NF-ΞΊB is a Central Regulator of Hypoxia-Induced Gene Expression Hypoxia is both a physiological and pathological signal in cells. Changes in gene expression play a critical role in the cellular response to hypoxia, enabling cells to adapt to reduced oxygen availab...

Delighted to finally share our latest preprint on the role of NF-kappaB in hypoxia. Quite a few surprises!! www.biorxiv.org/content/10.1...
Have a look!

09.01.2025 10:57 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Done πŸ‘πŸ»

07.01.2025 21:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

All the best for 2025

31.12.2024 19:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

My first 3 years as a TTF we're filled with grant rejections, including an MRC NIRG that I was devastated about. It's similar for many others, just not talked about as openly as the successes. Resilience is important in research. When you get that first break you can start to build some momentum.

17.12.2024 16:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

...and we're hosting the British Toxicology Society annual meeting here in May, if you can make it. Details here: www.thebts.org/events/bts-a...

14.12.2024 15:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Sounds great. You should visit us in Liverpool when you're settled in Cambridge. Lots of folks here interested in drug and chemical toxicity. I'm sure they'd be interested to hear about your work.

14.12.2024 15:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

As a recent recipient of this funding, I can highly recommend it as a means of broadening experiences and networks to support current and future research.

12.12.2024 09:37 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Have you heard about TherEx, #LivUni's Centre for Experimental Therapeutics?

The TherEx mission is to improve health and wellbeing by optimising the use of existing drugs and accelerating the development of new treatments.

Making medicines better.

➑️ www.liverpool.ac.uk/centre-for-e...

05.12.2024 11:06 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Nice Christmas lunch combining with several @livunihls.bsky.social groups. And yes, I know it's not even December yet!

28.11.2024 16:39 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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MRC DiMeN Doctoral Training Partnership: Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans at University of Liverpool on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans at University of Liverpool, listed ...

Fully funded MRC DiMeN PhD studentship available in my group starting October 2025. Come work with us in Liverpool!

Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans

Deadline 13 December 2024

Informal enquiries welcome

Details here...

27.11.2024 11:14 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Done πŸ‘πŸ»

27.11.2024 11:08 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Done πŸ‘πŸ»

27.11.2024 10:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Done πŸ‘πŸ»

26.11.2024 18:15 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Registration and abstract submission now open for the 2025 British Toxicology Society annual congress. Student and carer bursaries also available. Join us in May for a great meeting in Liverpool!

www.thebts.org/events/bts-a...

26.11.2024 11:16 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1

No, maybe you were recalling the trial that Evgen (now TheraCryf) are planning for their sulforaphane based drug: theracryf.com/pipeline/#sf...

26.11.2024 11:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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