Marcos Aranda

Efficient mixed representation of active and passive motion in the mouse visual thalamus during natural behaviour During natural behaviour, changes in the visual scene are largely driven by the subject’s own movements, which can be actively generated (e.g., walking) or passively imposed by external forces (e.g., ...

Delighted to share our latest preprint. It's been a long time coming. Thanks to all the authors for their unique contribution and for for their patience. We show how the visual thalamus deals with active and passive head motion in freely moving animals: www.biorxiv.org/content/10.1...

This is really cool, congrats!

Thank you for the invitation @weillcornell.bsky.social! Fantastic discussions and inspiring colleagues!

We’re hiring! Join the Sivyer Lab at The University of Sydney as a Postdoctoral Research Fellow in Neurodegeneration within the Snow Vision Accelerator, a $50M initiative tackling glaucoma and optic nerve disease. iPSCs, electrophysiology, drug discovery, and gene therapy.

Zebrafish use spectral information to suppress the visual background Vertebrate eyes first evolved in water, where spectral content rapidly fades with distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the background, pointing to distance es...

Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'

Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social

@cellpress.bsky.social @cp-cell.bsky.social

👇🏻
www.cell.com/cell/fulltex...

Yay! Congrats Chiara and team 🎉

Two new papers to... er... skeet? Blurt? Bluert?

First is that our paper on the transcription factor Adnp and the ChAHP chromatin remodelling complex is now out.
www.pnas.org/doi/10.1073/...

I already blurted the paper here: bsky.app/profile/pier...

Retinal glia regulate development of the circadian photoentrainment circuit Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…

Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...

Dark purple poster displaying an art competition with a prize of £250. Competition is for art displaying the lab's research on sleep & mental health. Poster contains images of a person with EEG on their face and an image of a mouse dreaming of a maze and replaying memories. Deadline is stated as 31st December. There is a QR code and a website link at the bottom of the poster.

£250 Visual Art Prize Competition!
We're looking for art work to represent our research on sleep & mental health. Deadline: 31st December!

More info here: www.sleepengineering.co.uk/art-call-out

Circadian variation in MGMT promoter methylation and expression predicts sensitivity to temozolomide in glioblastoma - Journal of Neuro-Oncology Purpose Recent studies show that glioblastoma (GBM) is more sensitive to temozolomide (TMZ) in the morning. In cells, inhibiting O6-Methylguanine-DNA-Methyltransferase (MGMT) abolished time-dependent ...

#Circadian #medicine tests if treatment timing can improve patient outcomes. This paper by @mariafelicita.bsky.social @oliviawalch.bsky.social et al considers #chronodiagnostics ...how the outcome of a standard test for glioblastoma differs with time of biopsy. link.springer.com/article/10.1...

For your enjoyment (by @jagarikin)

Faculty Position in Anatomy, Physiology & Cell Biology We are seeking an outstanding integrative physiologist (broadly defined) for the position of Assistant Professor (tenure track) to join our faculty in the Department of Anatomy, Physiology, and Cell Biology in the School of Veterinary Medicine (SVM), UC Davis. Our department is a highly integrated group of faculty studying molecular, cellular, physiological, and pathophysiological mechanisms of health and disease. The candidate should have an active research program that focuses on interdisciplinary physiology research using state-of- the-art approaches. We welcome research which diversifies our expertise, and/or that which complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory systems as well as developmental biology. Candidates are expected to expand access to education and provide opportunities in research for students, trainees, and the community across various life and professional experiences. • Candidates must possess a PhD and postdoctoral experience in physiology or a related field. • Aptitude/experience in teaching broad-based physiology or functional anatomy to professional or graduate students. • Experience with grant writing. • Excellent interpersonal and communication skills, and a demonstrated ability to work cooperatively and collegially within a diverse community.

Sunrise at UC Davis School of Veterinary Medicine

Sunrise in Davis CA

Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social

Nice to find my research images decorating the department offices 🙂

Vision scientist Teresa Puthussery receives MacArthur ‘genius’ award - Berkeley News Puthussery’s discoveries about the retina are paving the way for new treatments for eye disease and vision loss

Teresa Puthussery, a UC Berkeley vision scientist whose insights into the retina could one day help those with vision loss regain their sight, has been named a 2025 MacArthur “genius” Fellow. news.berkeley.edu/2025/10/08/v...

Introducing CellTransformer, a new AI tool developed with UCSF that makes it easier to explore massive neuroscience datasets and identify important subregions of the brain. 🧵

The Rod Bipolar Cell Pathway Contributes To Surround Responses In OFF Retinal Ganglion Cells Sensory neurons can be influenced by stimuli beyond their receptive field center, yet the mechanisms underlying this surround modulation remain poorly understood. In the retina, many OFF ganglion cell...

🚨 New preprint out from our lab!
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...

Finally, we demonstrate that these genetic programs are essential for ipRGC-driven behaviors, linking molecular identity to function ☀️/🌛👁️🌈

BRN3B also shapes the morphological features that distinguish ipRGC subtypes!

In collaboration with @jakebhoi.bsky.social, we showed that BRN3B contributes to the electrophysiological properties 🤩!

We also discovered that BRN3B regulates melanopsin expression even in adult mice, highlighting a role beyond development!

In collaboration with Yue Yang, Tomoko Yamada, and Omar Payan Parra, we found that the transcription factor BRN3B tunes the molecular identity of ipRGC subtypes.

Genetic tuning of retinal ganglion cell subtype identity to drive visual behavior Nature Communications - This study reveals that graded expression of the transcription factor BRN3B fine-tunes the identity and function of melanopsin-expressing ipRGC subtypes in the retina....

Our paper is out today! In @tiffmschmidt.bsky.social lab, we identified a single transcription factor, BRN3B, that shapes multiple, key features that define diverse ipRGC subtypes🧬👁️🐭

Amazing work! Congrats

@samidodino.bsky.social

Congrats!

In case this is helpful for anyone, here is a post on how to get a job in french academia : trialsanderrors.substack.com/p/getting-a-...
Aimed at non-french scientists who are curious, but french ones may find it useful too.

Delighted to announce this spring semester's programme for our Seminar Series "Current Topics in Circadian & Visual Neuroscience", featuring a roster of speakers discussing their cutting-edge research in vision and/or circadian rhythms. Register now!

www.tscnlab.org/seminar

Molecular mechanism establishing the OFF pathway in vision Nature Communications - LRFN2 in cone photoreceptors is vital for building the OFF pathway. Here authors report this cell-adhesion molecule stabilizes contacts with OFF bipolar cells, clusters...

The ON/OFF dichotomy is fundamental to visual processing. In a new study led by Flori Soto, we identify a conserved molecular mechanism establishing the OFF pathway. rdcu.be/eikoa

Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning Avoidance learning—learning to avoid bad outcomes—is an essential survival behavior. Dopamine signals are widely observed in response to aversive stim…

Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti...

"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"

Congrats, Gaby!!!

I am sorry for your loss Bryan ❤️‍🩹