Katie Thompson-Peer

Figure from the preprint showing sensory neuron morphology with different levels of Cas9 expression.

High levels of Cas9 are toxic in sensory neurons. Reducing Cas9 levels with uORFs avoids toxicity and is compatible with efficient editing. From @thompsonpeerlab.bsky.social. Fly lines @vdrc-flies.bsky.social

#CRISPR #Drosophila

www.biorxiv.org/content/10.1...

They're going to send out the slides, I think. Not sure about a recording. But there are 4 of 5 sessions coming up, over the next 4 weeks, if you have time!

Just sat through the 1st of 5 webinars on "Raising a Resilient Scientist" from NIH OITE (Office of Intramural Training and Education).

I've done lots of mentorship training. This one, on communication skills, was a step above.

Highly recommended for PIs. www.training.nih.gov/raising-a-re...

That sounds like what NewPISlack is already doing, in case you want to join an established community.

We cannot scicomm our way out of this, part …I-don’t-know-I’m-tired-of-counting

@ucirvine.bsky.social @ucibiosci.bsky.social

How It's Made Panel - Center for the Neurobiology of Learning and Memory | UCI CNLM Click to Register HOW IT’S MADE: NEUROSCIENCE Ever wonder how neuroscience research really works? Join us for a virtual panel open to the public featuring UCI neuroscience experts in human…

🗓️ June 18 | 6:00–7:30 PM | Zoom

🎟️ Free & open to everyone — students, teachers, families & lifelong learners

🔗 Register here loom.ly/2rR_Uxo

🧠 Ever wonder how neuroscience discoveries are made?
From fruit flies to human memory, join us for a behind-the-scenes look at how brain science happens — straight from the experts at UC Irvine! 🔬✨

How It's Made flyer

I'm looking forward to participating in this interactive, family-friendly panel designed to make neuroscience accessible and exciting for all:

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

A screencapture of the page dedicated to the transcription factor isl1/tailup. There is information about the flybase ID, function, classification, keywords, and a very long wall of text under BIOLOGICAL OVERVIEW. Fly people rock tbh

The Interactive Fly logo, showing a cartoon of two adult Drosophila melanogaster on a yellow background. There's subtext that reads "A cyberspace guide to Drosophila development and metazoan evolution".

Did you know? 🧪 "The Interactive Fly" is a wonderful website hosted by @socdevbio.bsky.social where you can learn about their development, the history of gene discovery/name, and it is full of super useful resources for the #DevBio community 🪰https://www.sdbonline.org/sites/fly/aimain/1aahome.htm

Fantastic visit from @marthabhattacharya.bsky.social to UC Irvine’s Dept of Developmental and Cell Biology yesterday.

Beautiful science, studying the role of a transmembrane protein across many model systems.

Thanks for visiting!

It makes me sad every week.

Katie and Belén at the Dynamic Women Awards.

Today I received the 'Committee Spotlight Award' from the @ucirvine.bsky.social Women's Center for Success at the Dynamic Women Awards. What an honor! Thank you to the people who nominated me for this recognition, including Belén Torrado.

I loved training as part of the Boston C elegans research community. The generosity and curiosity were infectious.

One of three sets of poster presenters at the UC Irvine Bren center

Things giving me hope these days: seeing all the undergrads presenting their research. Our lab has 4 undergrads presenting today. I’m proud of them and their grad student mentors. @ucirvine.bsky.social @ucibiosci.bsky.social Happy UROP day.

Congratulation, Dr Prange!!
@sciencey-syd.bsky.social

Defense tomorrow! @sciencey-syd.bsky.social

@ucirvine.bsky.social @ucibiosci.bsky.social

In this midst of everything, I'm delighted to share that I've been selected for the Tom Angell Fellowship Award from the UCI Graduate Division. Award recipients demonstrate outstanding mentorship by going above and beyond their normal duties to create new opportunities to mentor UCI students.

@javierira.bsky.social is one lab alum

Fred Ausubel's lab worked in both C elegans and Arabidopsis. He's now retired, but maybe ask some of the lab alums about it? This lists former lab members ccib.mgh.harvard.edu/ausubel#team

This week’s main story is about the budget and staffing cuts being made to public health agencies in the U.S. under RFK Jr.’s leadership, how those cuts will impact all of us, and some foolproof ideas for what scientists can do in the absence of totally superfluous stuff like, y’know, centrifuges.

Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron–glia interactions in Drosophila | PNAS Extrinsic factors and the interactions of neurons with surrounding tissues are essential for almost every aspect of neuronal development. Here we d...

CD4-tdGFP and CD4-tdTomato do better than CD8-GFP for getting into the smallest tiny dendrites. They mark cell membranes beautifully. Look at Fig 1 e-g in www.pnas.org/doi/10.1073/... Available from BDSC

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

Satellite EMBO Neurocytoskeleton #neurocyto2025 meeting at Torres del Paine?

Went on an amazing hike with Karolina Kowalska and Jonas Vlasak from Daniel Rozbesky's lab.

Then ran into @roylab-ucsd.bsky.social and @m1singh.bsky.social the next day.

Great to see colleagues in beautiful places!

Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...

Meeting with new and reconnecting with old colleagues in Santiago today. Thank you to my host, Evelyn Avilés!!

Having a great time at the EMBO Neurocytoskeleton meeting #neurocyto2025. Fantastic meeting in Chile!

This article does a great job describing the lives of young American scientists:

“You roll up your sleeves, try to make or discover something useful and then let the scientific community try to punch holes in your work to make sure that it’s sound”