Matt Padula

Yes. I watched the film this morning. The noise is excellent and why I love rally cars.

I wasn't at my cathedral for the supercars but will be for the GT3 race in February. Better class of crowd.

The car that ruined Group A touring car racing, especially in Australia.

Orbitrap Velos ETD - Thermo | BMSF The Orbitrap Velos ETD is a hybrid instrument that incorporates both Orbitrap and linear ion trap mass analysers; both 1D and 2D nano liquid chromatography (LC) separations can be interfaced to this i...

Apparently BMSF have an Orbitrap Velos with ETD: www.unsw.edu.au/research/fac...

QE+ is one option, but have access to other Thermo instruments including a Velos.

I was reading your 2022 primer.

It will most likely be the QE+ but can also use what is available at BMSF/UNSW.

Having avoided glycopeptides for years, I now need to analyse them. Can someone point me in the direction of useful publications that describe the practicalities of doing this properly to maximise data quality? Source conditions, fragmentation settings etc. Thanks.

We were dumb enough to let this happen....

Depends on what division within the structure you fall under. I struggle to get either from Central, as do all the facilities. But other places are happy to hire staff but not renew infrastructure. Most accounting practices are horseshit IMHO.

ProteoformDB: A Built-In Application to Generate Proteoform Database pubs.acs.org/doi/10....

---
#proteomics #prot-paper

The unalterable fact that all skills are perishable is something you only learn through experience.

USyd is sitting on a $500 million surplus......and thinking about cutting staff.

I believe the University is kicking in some more cash.

I'm going to have to look at those. They look like something another company made ~15 years ago (Brownlee?)

I’m turning down journal reviews if the journal doesn’t update activities to ORCID. I get a lot of requests and I need to prioritize somehow. I ain’t collecting “reviewer certifications” from Genome biology and scientific reports, etc., when Nature Family and ACS give me credit for my time.

I'd be fooled. That just looks like a union.

Am I the only (grumpy) person annoyed when an email starts with "I hope this email finds you well"?

So tempted to reply with "Actually it doesn't find me well. Still have cancer."

Just get to the point of why you are contacting me please.

Proteoform Mapping Calls for a Combined Effort From Bottom‐Up and Top‐Down Proteomics analyticalsciencejou...

---
#proteomics #prot-paper

"Biomarker studies are the greatest reproducibility crisis in science" (M. Uhlén, 2025).

Thinking about putting this sign outside my facilities door . 🤔

Tell students why it is important to do so would be a good start. And make sure that we, as authors and reviewers, demand rigour in what we submit and review. It's not difficult.

To be honest, when I see conferences announced that have a majority of male invited speakers, I think the organisers are not trying hard enough. We have so many excellent #FemalesinMS and resources available there is really no excuse for it anymore #massspec #teammassspec #lipidomics #metabolomics

🎤 Get ready for more ANZMetSoc ECR Rapid-Fire!

Hear 3min talks from 2 of 10 #ECR speakers:
Emily Sunnucks (UT Sydney) on multi-omics & death 🧩Chrystal O’Connor (Lincoln Uni, NZ) on Indigenous-guided metabolomics 🌿

📅 Oct 29
🏆 Vote People’s Choice: tinyurl.com/ECR-Rapid-Fire
#ANZMetSoc #Metabolomics

Screenshot of the first page of a Noûs article titled “Causal Inference from Noise.” Authors: Nevin Climenhaga (Australian Catholic University), Lane DesAutels (Missouri Western State University), and Grant Ramsey (KU Leuven). The citation details read: Noûs 55:1 (2021), pages 152–170, DOI: 10.1111/nous.12300.

Correlation isn’t causation, as the mantra goes—but statistical noise in correlational data can reveal causal information. When X and Y are causally linked, their noise tends to be asymmetric & this can guide #CausalInference. Check out our 📃👇 doi.org/10.1111/nous... #philsky #philsci #StatsSky #HPS

That's an interesting point that never occurred to me. That's awesome.

AlphaDIA enables DIA transfer learning for feature-free proteomics - Nature Biotechnology An open-source platform for data-independent acquisition proteomics adapts predicted libraries to experimental settings.

AlphaDIA enables DIA transfer learning for feature-free proteomics - @mannlab.bsky.social @jalew188.bsky.social go.nature.com/4qmEQMM

Principles for proper peer review

I'll just leave this here: jocnf.pubpub.org/pub/qag76ip8...

16/36 riders. I'll take that.

Matrix directs trophoblast differentiation in a bioprinted organoid model of early placental development - Nature Communications The placenta plays vital roles in supporting fetal development. Here, Richards et al. develop a high-throughput bioprinted trophoblast organoid model to recapitulate the microenvironment of the e...

Read more in @natcomms.nature.com by:
@clairerich.bsky.social
@lanamcclements.bsky.social
@mattpadula.bsky.social
@louisecole.bsky.social

🏫
@utsengage.bsky.social
@centenaryinstitute.bsky.social
@hmriaustralia.bsky.social
@garvaninstitute.bsky.social

www.nature.com/articles/s41...

Well, I had a "lie down" on a warm up of a stage. But got through the rest of the race. No idea of times, but I got third in class (yes, only 3 entries). Actually had fun. Typical loose Sydney dry dirt despite all the rain of last few weeks.