Chris J. Maddison

Our friends in Pharmacology + Toxicology at the @uoftmedicine.bsky.social @uoft.bsky.social are looking for an assistant professor! The successful candidate will also become a member of the Acceleration Consortium. Apply now: jobs.utoronto.ca/job/Toronto-...

Thanks, Marc!

There's a very strong tendency to believe that the medical system has answers for the ailments that you or your loved ones will inevitably develop. Unfortunately, it's not true. The sooner we internalize that, the sooner we fix biotech.

MABs and LLM-assisted coding are what blew my mind this year.

https://www.cs.toronto.edu/~cmaddis/letters/dear_friends_2024.pdf

Merry Christmas, friends and colleagues! I've written a short letter reflecting on our progress. Thank you for everything.

www.cs.toronto.edu/~cmaddis/let...

Boosting the Predictive Power of Protein Representations with a Corpus of Text Annotations Protein language models are trained to predict amino acid sequences from vast protein databases, while learning to represent proteins as feature vectors. These vector representations have enabled impr...

We have done a similar feat for protein sequences @martaowesyou.bsky.social @cmaddis.bsky.social : www.biorxiv.org/content/10.1...

Fun polio fact: it is asymptomatic in 70% of cases.

In 29.5% of the cases symptoms do appear, they are gastrointestinal distress, normal enterovirus stuff.

Polio only displays neurological symptoms in 0.5% of cases.

You don't remember polio, you only remember *longpolio*

Come visit us at 11am, West Ballroom A-D #5110. Target trial emulation with LLMs and social media data! 🎉📣

@nikitadhawan.bsky.social developed NATURAL (www.cs.toronto.edu/~nikita/natu...) with @cottascience.bsky.social , Karen & @cmaddis.bsky.social. Its an end-to-end pipeline that starts from raw-text data and ends with a causal (**) effect associated with an intervention.

(**) conditions apply
🧵(6/7)

I haven't gone since 2019 because I've had very significant health challenges due to COVID19. This year the conference is near family, so it's more accessible to me.

I will be @neuripsconf.bsky.social next week (first time since 2019!). Please reach out if you'd like to connect.

Unless we hold reviewers and ACs accountable, especially ACs in this case, the acceptance of a paper will be determined by whether your paper got active or inactive reviewers/ac. This is even worse and more frustrating than the usual reviewer quality lottery.

At the moment the disease is defined clinically as symptoms lasting more than 3 months after COVID19.

Why long COVID may simply be 'long infection' - ABC listen A parliamentary inquiry found between two and twenty per cent of Australians who get the virus will develop symptoms of long COVID including brain fog and fatigue, but its exact causes remain a myster...

Why long COVID may simply be 'long infection'.

It is very important to make the message simple and optimistic: it seems that some people have long SARS-CoV-2 infections. We now know what we need to do.

www.abc.net.au/listen/progr...

You can't be in all three, Dan.

Really hope this platform succeeds because I have my preferred username.

Hi Siebe 👋

Never going back to LaTeX tables and matplotlib scripts without Claude.

Moving my work in this direction, would love to be added!

Thanks!!!

Me!

A tale of two platforms:

BlueSky user numbers have hit a new record high in recent days, while the number of people deleting their accounts on X/Twitter has rocketed 🚀

I created a starter pack of faculty members / researchers at the University of Toronto from across academic disciplines, faculties, and campuses.

I tried to find as many as I could. Please let me know which additional colleagues to add.

go.bsky.app/GjLWXGA #UofT

A homemade loaf of bread.

Sunday:

cmaddis is my preferred handle. an accident of history.

Great point, Elisa.

Oh, yes.

A common raven looks over its shoulder, coquettishly

Common raven

I feel like LLMs might unlock a new age, no?