Stephen Lapinsky

Please follow @woccs.bsky.social our new Obstetric Critical Care resource and website WOCCS.org

Hypertensive Disorders of Pregnancy and Long-Term Risk of Dilated Cardiomyopathy This population cohort study uses multiple linked UK electronic health records to examine whether hypertensive disorders of pregnancy are associated with long-term risk of dilated cardiomyopathy.

UK population-based cohort study including 14 083 patients with hypertensive disorders of pregnancy.
HDP associated with a doubling of the risk of developing dilated cardiomyopathy. Risk was increased with severity of preeclampsia, older maternal age & postpartum hypertension.

ja.ma/3Fwf0n2

Asthma in pregnancy
Study from the Albert Pregnancy Birth Cohort, incidence of asthma was 8.6% & maternal asthma associated with 15% higher risk of PTB, an 11% higher risk of LBW, and a 10% higher risk of C-section. Risk increased with active asthma

www.jaci-inpractice.org/article/S221...

OBGYN Advances in cancer care have led to a growing number of cancer survivors globally. As cancer increasingly affects women and people of reproductive age, more individuals will be experiencing pregnancy....

Detailed overview of
“Pregnancy after cancer: FIGO Best practice advice”
in IJGO, by Dr. Cindy Maxwell of @sinaihealth.bsky.social & international experts.

obgyn.onlinelibrary.wiley.com/doi/10.1002/...

Mechanism of preeclampsia: fascinating talk @nasom-obmed.bsky.social 2025 by Dr. Surendra Sharma on the role of impaired autophagy related to tau protein aggregation, and treatable with trehalose

pubmed.ncbi.nlm.nih.gov/38760513/

Top 5 articles in OB Medicine in 2024 presented at @nasom-obmed.bsky.social 2025 meeting

Jayson Potts opening the @nasom-obmed.bsky.social 2025 meeting in Newport, RI

New review on PlGF & sFlt1 in Obstetic care, by @sinaihealth.bsky.social leaders in the field.

journals.sagepub.com/doi/10.1177/...

NASOM annual conference coming up April 25-26, Newport, Rhode Island

Participate in person or virtually

Program:
nasom.org/wp-content/u...

Register at:
nasom.org/event-regist...

Catherine Nelson-Piercy is on BlueSky!

@nelson-piercy.bsky.social

Risk of Major Congenital Malformations Following Prenatal Exposure to Smoking Cessation Medicines This cohort study examines whether prenatal use of smoking cessation pharmacotherapies is associated with increased risks of major congenital malformations.

Smoking cessation drugs in pregnancy: large cohort study of 1st trimester exposure shows no significant increased risk of congenital malformations with nicotine replacement & varenicline. (similarly no increased risk for buproprion but limited data)

jamanetwork.com/journals/jam...

What Obstetric Health Care Providers Need to Know About Measles and Pregnancy From January 1 to April 3, 2015, 159 people from 18 states and the District of Columbia were reported as having measles. Most cases are part of an outbreak linked to a California amusement park. Becau...

Since @greenjrnl.bsky.social & @acog-org.bsky.social have recently joined Bluesky and - sadly - #measles is going to be ongoing public health crisis in 2025, I'd like to mention their resources on this topic #ObGynSky + #ReproSky + #MedSky.

pmc.ncbi.nlm.nih.gov/articles/PMC...

New research examining subcapsular liver hematomas in preeclampsia and HELLP syndrome: ow.ly/M7vR50Vj7OR

Excellent podcast by Catherine Nelson-Piercy and Marie Teil discussing the challenges women with chronic medical diseases face in pregnancy, the lack of data to inform decisions, and the move towards including pregnant women in research studies

scanmail.trustwave.com?c=8248&d=jaz...

Time to register for NASOM 2025
April 25-26, Newport, Rhode Island

Or participate virtually!

Early bird rate ends March 31st

nasom.org/current-year...

Hundreds of research grants at Columbia canceled following Trump edict, administrator says The National Institutes of Health is terminating 232 grants for scientific research at Columbia University Irving Medical Center, according to an email an administrator sent to faculty.

I received one of the 232 NIH grant "terminations" sent to scientists at Columbia last night. My research focuses on improving maternal and child health in the US. Also affected: ongoing clinical trials, research training programs, and research centers that aim to improve the health of Americans.

Obstetrics & Gynecology, the Green Journal, has left Twitter and is now here!

@greenjrnl.bsky.social

Letter from NASOM President, Jayson Potts, regarding the upcoming NASOM conference.
- now a virtual option
- added session on impact of political changes on women's health

𝙉𝙚𝙬𝙥𝙤𝙧𝙩, 𝙍𝙝𝙤𝙙𝙚 𝙄𝙨𝙡𝙖𝙣𝙙 𝙤𝙣 𝘼𝙥𝙧𝙞𝙡 25 & 26, 2025

Details & registration at:

nasom.org/current-year...

Pregnancies in women after peri-partum cardiomyopathy #PPCM: global ESC EuroObservational Registry

#CardioSky #CardioObstetrics
academic.oup.com/eurheartj/ad...
@escardio.bsky.social @jgrapsa.bsky.social @anastasiasmihaili.bsky.social @garimasharmamd.bsky.social @emilyswlau.bsky.social

Cystic fibrosis & pregnancy

New data from American Cystic Fibrosis Foundation Patient Registry.

Pregnancy assoc with:
- reduced hazard of death compared to never-pregnant
- no significant impact on lung function.

www.sciencedirect.com/science/arti...

I never really thought much about where our fruit came from, but now that we buy non-American, these Italian & Israeli options are great! 🇨🇦

Hemophagocytic Lymphohistiocytosis | NEJM HLH, a cytokine-mediated hyperinflammation syndrome, causes fever, pancytopenia, and hemophagocytosis and is often fatal. Antiinflammatory agents, etoposide, and interferon-γ antibody are the main ...

Comprehensive review of HLH in the N Engl J Med

www.nejm.org/doi/full/10....

Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

Another report of pregnancy associated HLH in @OBMedicine, with no driver identified. Important to also highlight the role of anakinra & the 3Fs (fever, falling counts & ⬆️ ferritin) as a quick screen. In the UK, also remember the HLH MDT & @NPEU_UKOSS study.

journals.sagepub.com/doi/10.1177/...

I like this, will try! I usually give a 1-2 hr trial of vasopressin. There are definitely vasopressin responders and non-responders - I view it as replacing a hormone deficiency rather than acting purely as pressor.

Well Alberta, we (in Toronto) accepted your overflow critically ill COVID patients in 2021. Remember, if they come here they receive evidence-based medicine, no ivermectin included!

External aortic compression in OB hemorrhage by Alvaro Nieto-Calvache. A simple maneuver to control bleeding and buy time

www.ajog.org/article/S000...

And video:
www.ajog.org/cms/10.1016/...

Early warning scores in maternal sepsis
Detailed evaluation of several EWS in a large WHO database of OB sepsis:
- OB & sepsis specific scores performed better
- none accurate enough for clinical use
- incomplete data is a problem

www.thelancet.com/journals/ecl...

Pregnancy in Adult Congenital Heart Disease

#CardioObstetrics #ACHD #CardioSky #MedSky
www.acc.org/Latest-in-Ca...
@accintouch.bsky.social @shantelleb.bsky.social @isabellemalhame.bsky.social @csilvers.bsky.social @garimasharmamd.bsky.social @erinmichos.bsky.social @mchonig.bsky.social

Top Articles Collection 2024

We are looking for your 3 favorite articles in Obstetric Medicine for 2024.

Submit these via the link below, and join us at our Annual Meeting in April for the presentation!

www.surveymonkey.com/r/NASOMTAC24