Radcliffe Department of Medicine

Wellcome Discovery Award for Claus Nerlov Claus Nerlov, Professor of Stem Cell Biology, has been awarded funding from Wellcome to map the gene regulatory networks in blood cell production and seek new therapeutic targets.

🎉 Congratulations to Prof Claus Nerlov, who has been awarded funding from Wellcome to map the gene regulatory networks in blood cell production and seek new therapeutic targets 🩸

Read more 👇

@rdm.ox.ac.uk | @wellcometrust.bsky.social

Nicholas Clarke

Congratulations and welcome to Nicholas Clarke - one of 28 exceptional young people awarded the 2025 Ramsey Postgraduate Scholarship 🎉

Nicholas will be studying how AI can be used to develop novel methods to detect cardiomyopathies on cardiac CT.

Read more 👇

shorturl.at/JFflX

New Study Links Cancer Stage to Strength of Antitumoral Immune Response in HR+ Breast Cancer The latest study from Tao Dong's Group in the MRC Translational Immune Discovery Unit has been published in Cell Reports Medicine.

NEW: Latest study from Tao Dong's Group links cancer stage to strength of antitumoral immune response in HR+ breast cancer 🧪

Read more 👇

@ndm.ox.ac.uk | @medsci.ox.ac.uk

Cardiovascular disease: new ways to detect risk and improve outcomes NIHR Evidence webinar exploring new ways to identify people at risk of cardiovascular problems. Methods used data and AI to identify cardiovascular risk.

Great to see our work on using AI with routine scans to predict heart attacks many years before they happen featured in this piece @rdm.ox.ac.uk @ouhospitals.bsky.social @medsci.ox.ac.uk
evidence.nihr.ac.uk/collection/c...

🎥 Explore how mentoring can help you navigate your working life and support your career development

🔄 Share to help spread the value of mentoring

Want to dive deeper?

👉 Join our upcoming Mentoring Catalysis workshop on Tuesday 9 September: ow.ly/YLS950WysHb

Immune cells show promise in treating hypertrophic cardiomyopathy A new study from scientists at the Radcliffe Department of Medicine and Harvard Medical School, and funded by the British Heart Foundation, has uncovered a potential new treatment for hypertrophic car...

A new study led by RDM researchers has found that immune cells may play a role in treating hypertrophic cardiomyopathy (HCM).

Read more 👇

shorturl.at/AmdBV

@harvardmed.bsky.social @thebhf.bsky.social @medsci.ox.ac.uk

Recruitment opens for UK-wide liver cancer imaging study | NIHR Oxford Biomedical Research Centre

A new UK-wide clinical study aimed at transforming liver cancer surveillance in people with #cirrhosis has opened to recruitment oxfordbrc.nihr.ac.uk/recruitment-... #LiverCancer @ouhospitals.bsky.social @medsci.ox.ac.uk @rdm.ox.ac.uk @nihr.bsky.social

Making it Personal – Engaging the public through theatre Innovative public engagement project explores the intersection of cutting-edge science and the raw honesty of the stage.

Have you ever considered using theatre to connect your research with the public?

Ali Kay (@genomics-ali.bsky.social) from the @gorielylab.bsky.social at the MRC WIMM has co-led a project that utilised theatre to explore a couple’s experience of a genetic diagnosis in their child.

Read more 👇

A technician oversees a patient in an MRI machine

The Medical Research Council has awarded a team co-led by RDM's Dr James Grist, £1.3 million to advance the field of hyperpolarised MRI 🎉

The project will develop educational tools for the field and conduct a multi-centre brain study.

Read more 👇

shorturl.at/1ZpRB

@ukri.org @medsci.ox.ac.uk

@kwrsmith.bsky.social, @kaitlyndennis.bsky.social and Leanne Hodson (@rdm.ox.ac.uk) review the effect of phenotype and diet on risk of intrahepatic triglyceride accumulation as part of our Dietary Manipulations special issue!

📜 buff.ly/vbtVwXH

Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome Key Points. Somatic preleukemic GATA1s mutations are acquired before birth in 25% of neonates with Down syndrome and are not acquired post-natallyRates of

NEW: Research led by Professors Irene Roberts and Paresh Vyas reports the outcome of the first-ever prospective study of newborn babies with Down syndrome, exploring why these babies and young children have such a high incidence of acute myeloid leukaemia caused by mutations in the GATA1 gene. 🧪

New tool allows researchers to track how mutations arise in tissues Researchers at the MRC Weatherall Institute of Molecular Medicine and the German Cancer Research Center (DKFZ) have developed a new method to analyse how our tissues evolve as we age.

NEW: Researchers at the MRC WIMM and @dkfz.bsky.social have developed a new method to analyse how our tissues evolve as we age, called SCIFER 🧬 🧪

Read more 👇

@rdm.ox.ac.uk | @medsci.ox.ac.uk | @ox.ac.uk

Celebrating science, collaboration and excellence at WIMM Day 2025 The MRC WIMM community gathered for its flagship annual event, WIMM Day, on Tuesday 24th June. Held at the Saïd Business School, the day showcased the breadth and impact of research across the institu...

WIMM Day 2025 brought our researchers together to share discoveries, swap ideas & celebrate success — from gene editing to immunotherapy to public engagement.

Catch the recap + award winners here:

Agne Antanaviciute, Mira Kassouf and Sumana Sharma

We are delighted to announce the designation of three new RDM Principal Investigators (PIs)🎉

Congratulations Agne Antanaviciute, Mira Kassouf and Sumana Sharma.

Read more 👇

shorturl.at/cAfw9

@imm.ox.ac.uk

🎙️ How does Ozempic actually work?

You might have heard about it in the media, but what actually *is* #Ozempic? Marketed as a drug for #diabetes, it is now commonly associated with #weightloss. We chat to #hormone doctor Annie de Bray about how it works.

🎧 pod.fo/e/2e38fe

New research reveals druggable target arising from chromosomal rearrangement in aggressive leukaemia Researchers at the University of Oxford have uncovered a potential new therapeutic target in a particularly aggressive and hard-to-treat form of leukaemia.

NEW: Researchers at the MRC Molecular Haematology Unit, led by @ckbrierley.bsky.social & @adammead.bsky.social, have uncovered a potential new therapeutic target in BP-MPN - a particularly aggressive type of leukaemia.
🧪🧬

Read more:

@oxfordbrc.bsky.social | @rdm.ox.ac.uk | @medsci.ox.ac.uk

Shijie Cai, Costas Christodoulides, Sarah Howles and Tess McPherson

We are pleased to announce that the title of Associate Professor has been conferred on four RDM researchers. 🎉

Congratulations to:

Shijie Cai
Costas Christodoulides
Sarah Howles
Tess McPherson

Read more about their areas of research 👇

shorturl.at/TVO0A

New research will map the impact of sleep and circadian rhythm disruption on cardiometabolic disease In the UK more than 4.3 million people live with Type-2 Diabetes, and 2.4 million more are at increased risk of developing the disease. Type-2 Diabetes, obesity, hypertension, and fatty liver disease ...

Type-2 Diabetes, obesity, hypertension & fatty liver disease often cluster together in the same people. Sleep and body clock problems have a role to play. David Ray is leading a team to find out how changes to the body clock contribute to #cardiometabolic disease.

www.rdm.ox.ac.uk/news/new-res...

Image showing details for Digital Communications Officer role, including a salary range of £34982 - 40855 and an application deadline of 12pm on the 25th June 2025.

We're hiring! An exciting opportunity has arisen to join us as Digital Communications Officer 📹 💻

This role will work closely with our Comms & Public Engagement Officer to support the delivery of our communication strategy and produce in-house audio-visual content.

Apply here: bit.ly/4jIheOt

Professor Charalambos Antoniades elected as new Fellow of the Academy of Medical Sciences The Academy of Medical Sciences has elected five University of Oxford biomedical and health scientists to its fellowship in 2025, including Charis Antoniades.

Congratulations to Charalambos Antoniades, who has been elected as a Fellow of the Academy of Medical Sciences in recognition of his work, which focuses on developing novel diagnostic tools for the early detection of cardiovascular diseases.

www.rdm.ox.ac.uk/news/profess...

@acmedsci.bsky.social

Congratulations to @agoriely.bsky.social on being awarded the Spinoza chair by @amsterdamumc.bsky.social 🎉

In June, Prof Goriely will give her Spinoza lecture on how new genetic mutations arise in the testes, their increase in frequency as men age, and how they can lead to serious genetic diseases.

Weight loss with Ozempic: from scientific lab to at-home jab Injectable weight loss drugs like Ozempic have captured headlines and stirred debate. But what do they actually do, and who are they for? Dr Annie de Bray-…

4/4 Amanda Adler will also be there to offer her perspective on how these drugs fit into the broader picture of healthcare and evidence-based treatment.

Book your tickets 👇

shorturl.at/ETSyx

3/4 Next, on Wednesday 21 May, Annie de Bray-Brown will explain how weight loss drugs like Ozempic work. Find out what they mean for people living with obesity and diabetes, and how hormones are changing the future of metabolic medicine.

Rebuilding the human: From the beating heart to organs-in-a-dish What can art, philosophy, and centuries of science teach us about the heart? Professor Robin Choudhury takes us on a journey through the story of the human…

2/4 At the same event, Abdullah Khan will bring us to the lab bench where scientists are growing mini organs to study human biology!

Book your tickets to this event via the link below 👇

shorturl.at/ut4XE

Pint of Science, 19-21 May 2025

1/4 RDM researchers will be hosting two events at this year's @pintofscience.uk 🎉

On Tuesday 20 May, Robin Choudhury will take us on a journey of the human heart, from ancient beliefs to modern breakthroughs 💥

YouTube video by Oxford BRC Predicting heart attacks years before they happen

❤️ This #HeartFailureAwarenessWeek, we’re highlighting how Oxford research is helping detect heart attack risks earlier. Kenneth Chan explains how CT + AI can spot hidden signs before arteries narrow.🎥 Watch the talk www.youtube.com/watch?v=8mzv...

@nihr.bsky.social @rdm.ox.ac.uk @thebhf.bsky.social

Study identifies key immune structures in the gut that may drive coeliac disease | NIHR Oxford Biomedical Research Centre

Researchers have found structures of immune cells in the gut that may drive the response to gluten in people with coeliac disease and could provide a target for future therapies oxfordbrc.nihr.ac.uk/study-identi... @ndm.ox.ac.uk @oxfordpaediatrics.bsky.social @imm.ox.ac.uk @medsci.ox.ac.uk

Flyer for Hoffbrand's Postgraduate Haematology, 8th Edition

Our researchers Adam Mead, Graham Collins and Deborah Hay have edited the eighth edition of this seminal #haematology text book, published by Wiley. Intended as a reference work and guide to the latest research in the field.
www.rdm.ox.ac.uk/news/rdm-res...

@graham74gc.bsky.social

Diabetes UK Early Career Investigator Award for Dr Thomas Hill Congratulations to Dr Thomas Hill who has received a Diabetes UK Early Career Investigator Award at the Diabetes UK Professional Conference.

Congratulations to Dr Thomas Hill who has received a Diabetes UK Early Career Investigator Award for the second year 🎉

Thomas' research aims to understand how to prevent hypoglycaemia in people with type 1 diabetes.

Read more 👇

shorturl.at/SekbA

@diabetesuk.bsky.social

Diabetes research: a world of colourful puzzles _"The whole thing feels a bit like doing a jigsaw puzzle where we have to find the pieces first..."_ Type 2 diabetes is one of the oldest known ailments. In fact, the Indian healer Sushruta described it in the 5th century BC as ‘madhumeha’, or honey-like urine, when he noticed that urine from sick people attracted ants. Fortunately, medicine has progressed a long way since this time, and Type 2 diabetes is now a condition that can be lived with. So, what actually causes the disease, and how can we treat it? Dr Daniela Nasteska from Oxford's Radcliffe Department of Medicine introduces us to the colourful world of diabetes research. With thanks to Diabetes UK for funding this research.

🎥 Dr Daniela Nasteska from @rdm.ox.ac.uk introduces us to the colourful world of #diabetes #research in our brand new video.

Watch it here: bit.ly/diabetes_puz... 🧩

@medsci.ox.ac.uk @wolfsonoxford.bsky.social @ox.ac.uk @dn-mk.bsky.social @daveyboyhod.bsky.social
#OxfordScience #Type2diabetes