Ravi Dashnamoorthy

#AACR2025, several rows of empty poster boards, some posters were not even attended. Changing interests and themes, crowds mostly focused on DNA repair/cell cycle inhibitors or Degraders. Not so much on CAR-T, Systems biology is lost in translation, not sure where cancer research is headed.

Hi All, please see this active discussion board, about a recent publication in Lancet Oncology, which is an insult to science and these authors have "0" credibility without any publications metabolism or clinical studies on this topic.
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Wafik S. El-Deiry, MD, PhD, FACP on LinkedIn: Ultraprocessed Foods High in Seed Oils Could Be Fueling Colon Cancer Risk Ultraprocessed Foods High in Seed Oils Could Be Fueling Colon Cancer Risk A new study suggests certain lipids, particularly omega-6 fatty acids, which are…

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Dr E. Shyam P. Reddy on LinkedIn: Widely used cholesterol-lowering drugs could harm and kidney health… Statins are widely prescribed to lower high cholesterol, a key factor in preventing heart attacks and strokes. Among these medications, rosuvastatin has…

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Ravi Dashnamoorthy, Ph.D on LinkedIn: URGENT: New Cancer Variant Strikes Ages 25-45 in Months, Not Years - 40%… Michael Attea, these are extremely important for public to know. Unfortunately, they are too busy to read and understand this. Despite my efforts to raise…

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An Analysis of Transcriptomic Burden Identifies Biological Progression Roadmaps for Hematological Malignancies and Solid Tumors Biological paths of tumor progression are difficult to predict without time-series data. Using median shift and abacus transformation in the analysis of RNA sequencing data sets, natural patient strat...

We recently mapped the biological progression maps in human tumors. This study shows how cancer can behave like "Charlotte's web" when it comes to targeting with precision medicine. How we can use certain drugs to reverse biological progression etc., pmc.ncbi.nlm.nih.gov/articles/PMC...

This study solves the mechanistic basis of 100 year old Warburg's paradox. Please show your support by reading/commenting about this study.

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Next big advancement in Antibody Drug Conjugate based therapy, customizable and cheaper.

Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma Background/Objectives: Warburg’s metabolic paradox illustrates that malignant cells require both glucose and oxygen to survive, even after converting glucose into lactate. It remains unclear whether s...

This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...

Dr. Ravi Dashnamoorthy, Ph.D on LinkedIn: Proteome-scale movements and compartment connectivity during the… This new research study (by Litsios et.al) based on yeast has tracked functional changes that accompany cell cycle progression aligns perfectly with my prior…

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Please add me to this starter pack, Thanks.

Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma Background/Objectives: Warburg’s metabolic paradox illustrates that malignant cells require both glucose and oxygen to survive, even after converting glucose into lactate. It remains unclear whether s...

This study clarifies Warburg’s paradox, showing glucose as a catalyst for oxidation and a substrate for nucleic acid synthesis, enabling faster cancer proliferation and highlighting its biological necessity in malignancy. doi.org/10.3390/canc...