Taufiq Ahmad

Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes - Journal of Orthopaedic Surgery and Research Background Ready-to-use non-aqueous cement pastes consist of an organic, water-miscible liquid phase in which cement powder is dispersed. While the modification of classical aqueous powder/liquid cement pastes with antibiotics has been extensively investigated, only a few studies previously published aimed at drug modification of premixed cement pastes. Methods A simple method for modifying such ready-to-use pastes with the model antibiotic vancomycin is described. It was demonstrated that mixing the cement paste and vancomycin solution multiple times using an adapter between two syringes resulted in macroscopically homogeneous pastes. The antibiotic-loaded cements were thoroughly characterized with regard to their physicochemical properties and their drug release profile. Results Drug modification with vancomycin had no adverse effects on cement properties in terms of mechanical performance, phase composition, porosity and pore size distribution. Drug release from ready-to-use pastes exhibited a lower initial burst release of 14.5% compared to 47.9% for aqueous powder/liquid cement pastes after 24 h. At later time points, the initial exponential release kinetics slowed down due to both a decreased concentration gradient and structural changes of the cement matrix during setting. This resulted in sustained release of the antibiotic for more than 30 days. The released vancomycin maintained high antimicrobial activity against S. aureus with inhibition zones of 5.4–6.8 mm in an agar diffusion test. Conclusion The results demonstrated that modification of ready-to-use cement pastes with vancomycin is a potential candidate for clinical application, as it preserves both the material’s properties and the antibiotic’s activity.

New publication from our Bone Cements group:
Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes
link.springer.com/article/10.1...

Later this week we will be in Dresden for the #DGBM German Society for #Biomaterials Annual Conference.
Here all our contributions you can look forward to

New publication in collaboration with Dr. Torsten Blunk's lab:
congrats @camillamussoni.bsky.social and colleagues
advanced.onlinelibrary.wiley.com/doi/10.1002/...

We had an absolutely amazing time at #ISBFWarsaw2025!
The #Biofabrication2025 conference always feels like a family reunion, it was good to catch up with friends and learn about the latest results and share what we've been up to!
It was truly inspiring to see the community come together once more.

Back from #ISBFWarsaw2025, what a fantastic time I had this week
I couldn't imagine a better way to conclude my phd journey in the #Biofabrication family than this.
I am grateful to the ISBF for granting me the IOP Best Poster Award at #Biofabrication2025.

we wrap a very productive conference day2 with lots of presentations and insights!
Congratulations to president elect prof. Groll, we wish you a successful term!
Time to enjoy the young scientist🧑🏾‍🔬 night ✨ full of partying and networking 💃🏽🕺🏼
#Biofabrication2025 #ISBFWarsaw2025

a new day of talks and poster, we already had 2 rapid fire talks early this morning, check out prof. Groll and prof. Jüngst's talks and Nathaly Chicaiza's poster today!
#Biofabrication2025 #ISBFWarsaw2025

another busy day over in Warsaw for #Biofabrication2025.
here the summary of our fantastic day of talks 📊 and posters 📃
#ISBFWarsaw2025

Today I presented my work on bioassembly via MEW scaffolds in the Rapid Fire Talk session early this morning.
Very honoured my abstract was selected and I could show more of what I'm up to.
#Biofabrication2025 #ISBFWarsaw2025

POSTER presentation day!
come by the poster area to have a look and a chat
and tomorrow I will present a rapid fire talk at 8.45 am
#Biofabrication2025 #ISBFWarsaw2025

I am so excited to share that the latest issue of
Advanced Healthcare Materials front cover will feature my design for our latest publication on #biofabrication of the glomerular filtration barrier. Worked very hard on this design, so proud!
doi.org/10.1002/adhm...

This study explores the fabrication of nanofibrillar scaffolds through the melt electrofibrillation of polycaprolactone to guide myogenic differentiation. The scaffolds provide nanofibrillar cues that promote cell organization and integration, mimicking key features of the ECM

💪🏼New paper! 💪🏼

Bioassembly of Myoblast Spheroids in Electrofibrillated Scaffolds for 3D #Muscle #Tissue #Biofabrication

onlinelibrary.wiley.com/doi/10.1002/...

NEW PUBLICATION!
my first first authorship is finally online Thanks to all coauthors @taufiqahmad.bsky.social for the work done: Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co-Culture
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Bioprinting for funCTION not just for fun and interdisciplinary work are the key conditions for evolving our field, brilliant plenary talk from prof. Groll at @eutermis.bsky.social

🚨Publication alert!
Hydrogels shrink in #3D_bioprinting and tissue engineering. We made efforts to minimize it.

Thrilled to see our paper in #Biomaterials now in press:
sciencedirect.com/science/arti...

Fantastic teamwork with OP Oommen Cardiff University Engel_FB_Lab @fau.de

Workshop time! Great ideas 💡 have come out from working together, let’s see what new projects will start from this meeting… #biofabrication #tissueengineering
@utrechtuniversity.bsky.social @uniwuerzburg.bsky.social

let's start buildng a #Biofabrication community on Bluesky: go.bsky.app/KjXNCwG

We now open our Network for Discovery symposium between @uniwuerzburg.bsky.social and @utrechtuniversity.bsky.social with an introduction from prof. Jüngst, prof. Groll and prof. Malda

In our first session we discussed our progress in #meltelectrowriting for cardio-vascular applications
#Networking4Discovery a Würzburg-Utrecht initiative

#Biofabrication strategies for the muscle-skeletal system #3dmodels and #tissueengineering with talks from the symposium organizers Tiziana and Lennard

Cartilage is a hot topic both in wuerzburg and in utrecht, one more intersection to explore for future cooperations #biofabrication #tissueengineering
#Networking4Discovery

Last session of the day before we start putting all our brains together to discover new ways we can all work together!

Streamlining the Highly Reproducible Fabrication of Fibrous Biomedical Specimens toward Standardization and High Throughput Biopolymer-based nano- and microfiber scaffolds can be designed to mimic collagen structures, rendering them highly attractive for, e.g., regenerative medicine. However, their production is often lim....

Just up on the net!
Streamlining the Highly Reproducible Fabrication of Fibrous Biomedical Specimens toward Standardization and High Throughput
onlinelibrary.wiley.com/doi/10.1002/...

A Versatile Method to Produce Monomodal Nano‐ to Micro‐Fiber Fragments as Fillers for Biofabrication This research introduces an innovative approach for efficiently generating fiber fragments as additives for 3D-biofabrication. Utilizing a sacrificial membrane, the method enables highly reproducible....

A Versatile Method to Produce Monomodal Nano- to Micro-Fiber Fragments as Fillers for Biofabrication
this is for the #fibers people in #biofabrication and #tissueengineering, here is one way to make fiber production efficient and versatile by cryocutting
onlinelibrary.wiley.com/doi/10.1002/...

Impact of Polymorphic Microfibers for Establishment of Neuronal Model The studied microfibers, with properties differing in size, mechanics, and surface chemistry, were conducted in a highly precise manner using electrospinning, MEW, and microfluidic spinning processes...

NEW PAPER!
Impact of Polymorphic Microfibers for Establishment of Neuronal Model
how will neural cells behave with fibers? do they like soft or stiffer fibers? do you know how cells move the fibers around?
onlinelibrary.wiley.com/doi/10.1002/...

New Paper!
Painting bio: A vector-based method for precise #Gcode generation across scales in #biofabrication
No more figuring out coordinates for your gcodes, you can just paint the path, for all sorts of printers and bioprinters api-journal.accscience.com/journal/arti...

We are grateful for the support from Uniklinik Erlangen, Uniklinik Würzburg, @Uni_WUE, @biofabwue.bsky.social , and @SFB_TRR225 @dfg for funding and facilities(C06).

#Biofabrication #Nanofibers #Bioreactors #KidneyResearch #TissueEngineering #BiomedicalResearch

Big thanks to all co-authors, especially first authors Camilla Mussoni and Anna Rederer. Special thanks to Vladimir Stepanenko and Frank Würthner for AFM analysis, Philipp Stahlhut for SEM imaging, and Prof. Jürgen Groll and Mario Schiffer for their invaluable leadership and insights.

🔑 Highlights:

Electrospun membrane mimicking the glomerular barrier
Bi-directional cell communication
Bioreactor with flow-induced shear stress
Endothelial fenestrations