Faculty of Pharmacy, TUMS

Trastuzumab Deruxtecan Versus Trastuzumab Emtansine for Human Epidermal Growth Factor Receptor 2 Positive Metastatic Breast Cancer: Cost-Effectiveness Analysis From Iranian Experience Is T-DXd worth it for breast cancer? Cost-effectiveness study: vs T-DM1, adds 1.7 QALYs at $1927/QALY—below Iran's threshold. Supports adoption for HER2+ MBC. #BreastCancer #HealthEconomics

Is T-DXd worth it for breast cancer? Cost-effectiveness study: vs T-DM1, adds 1.7 QALYs at $1927/QALY—below Iran's threshold. Supports adoption for HER2+ MBC. #BreastCancer #HealthEconomics
www.rimpacts.com/rd/p?c=10041... 📄DOI: doi.org/10.1186/s129...

Molecular and Biochemical Evidence of Edaravone's Impact on Dasatinib-Induced Ags Cell Senescence: A Promising Strategy for Gastric Cancer Therapy New hope for stomach cancer? Study shows edaravone+dasatinib boosts senescence, cuts AGS cell migration via p53, MMP2—may prevent metastasis. #CancerTherapy #Senescence

New hope for stomach cancer? Study shows edaravone+dasatinib boosts senescence, cuts AGS cell migration via p53, MMP2—may prevent metastasis. #CancerTherapy #Senescence
www.rimpacts.com/rd/p?c=10045... 📄DOI: doi.org/10.2174/0109...

Carbon Dots With Red Emission As Nanoprobe for Sensing of Heparin in Biofluids and Pharmaceutical Samples Quick heparin test? Study uses R-CDs from neutral red/thiourea for fluorescent detection—LOD 5nM, works in biofluids. Suggests cheap, non-invasive monitoring tool. #HeparinDetection #Nanotech

Quick heparin test? Study uses R-CDs from neutral red/thiourea for fluorescent detection—LOD 5nM, works in biofluids. Suggests cheap, non-invasive monitoring tool. #HeparinDetection #Nanotech
www.rimpacts.com/rd/p?c=10046... 📄DOI: doi.org/10.1039/d4ra...

Polarized Raman Spectroscopy of Aligned Dna-Wrapped Single-Wall Carbon Nanotubes Aligned nanotubes via DNA? Study wraps Poly(dT)20 on SWCNTs for self-assembly—Raman shows anisotropy. Hints bio-optics, nano-electronics apps. #Nanomaterials #DNA

Aligned nanotubes via DNA? Study wraps Poly(dT)20 on SWCNTs for self-assembly—Raman shows anisotropy. Hints bio-optics, nano-electronics apps. #Nanomaterials #DNA
www.rimpacts.com/rd/p?c=10046... 📄DOI: doi.org/10.1016/j.ca...

Corrigendum “The Chemotherapeutic Potential of Doxorubicin-Loaded Peg-B-Plga Nanopolymersomes in Mouse Breast Cancer Model” [Eur. J. Pharm. Biopharm. 94 (2015) 521–531, (S0939641115002945), (10.1016/J.Ejpb.2015.07.005)] Study oops? Correction updates figures on curcumin+doxorubicin—no change to conclusions on heart protection. #ResearchErratum #Cardiology

Study oops? Correction updates figures on curcumin+doxorubicin—no change to conclusions on heart protection. #ResearchErratum #Cardiology
www.rimpacts.com/rd/p?c=10047... 📄DOI: doi.org/10.1016/j.ej...

Development of a Bio-Inspired Phagocytic Stable Nanoghost With Anti-Inflammatory Properties for Management of Inflammation in Ulcerative Colitis Gut-healing ghosts? Study's monocyte-coated NPs with glibenclamide cut NLRP3, heal UC mucosa—biomimetic promise. #UlcerativeColitis #Nanotherapy

Gut-healing ghosts? Study's monocyte-coated NPs with glibenclamide cut NLRP3, heal UC mucosa—biomimetic promise. #UlcerativeColitis #Nanotherapy
www.rimpacts.com/rd/p?c=10047... 📄DOI: doi.org/10.1080/1061...

Comparison of Physico-Chemical Properties of Different Types of Orthopedic Acrylic Cement Bone cement safety? Study finds PMMA cements safe via H-NMR, low cytotoxicity—sets in >10 min. #BoneCement #Orthopedics

Bone cement safety? Study finds PMMA cements safe via H-NMR, low cytotoxicity—sets in >10 min. #BoneCement #Orthopedics
www.rimpacts.com/rd/p?c=10056... 📄DOI: doi.org/10.1080/0920...

Doxorubicin Loaded Exosomes Inhibit Cancer-Associated Fibroblasts Growth: In Vitro and in Vivo Study Can exosomes beat breast cancer resistance? Study shows exosome-delivered doxorubicin boosts cancer cell death, reducing tumor size. #BreastCancer #Nanomedicine

Can exosomes beat breast cancer resistance? Study shows exosome-delivered doxorubicin boosts cancer cell death, reducing tumor size. #BreastCancer #Nanomedicine
www.rimpacts.com/rd/p?c=10057... 📄DOI: doi.org/10.1186/s129...

Synergistic Effects of Doxorubicin Loaded Silk Fibroin Nanoparticles and Cu-Tio2 Nanoparticles for Local Chemo-Sonodynamic Therapy Against Breast Cancer Can sound waves boost cancer therapy? Study finds sonodynamic therapy with DOX hydrogel enhances tumor inhibition. #CancerTherapy #SonodynamicTherapy

Can sound waves boost cancer therapy? Study finds sonodynamic therapy with DOX hydrogel enhances tumor inhibition. #CancerTherapy #SonodynamicTherapy
www.rimpacts.com/rd/p?c=10060... 📄DOI: doi.org/10.1016/j.ij...

Exosomes and Their Distinct Integrins Transfer the Characteristics of Oxaliplatin- and 5-Fu-Resistant Behaviors in Colorectal Cancer Cells Do exosomes drive cancer resistance? Study finds integrin levels in exosomes influence colorectal cancer resistance. #ColorectalCancer #Exosomes

Do exosomes drive cancer resistance? Study finds integrin levels in exosomes influence colorectal cancer resistance. #ColorectalCancer #Exosomes
www.rimpacts.com/rd/p?c=10063... 📄DOI: doi.org/10.1186/s100...

Molecular Evidence of the Inhibitory Potential of Melatonin Against Sodium Arsenite Toxicity Can melatonin protect against toxins? Study finds MLT reduces arsenic-induced pancreatic damage in rats. #Melatonin #ArsenicToxicity

Can melatonin protect against toxins? Study finds MLT reduces arsenic-induced pancreatic damage in rats. #Melatonin #ArsenicToxicity
www.rimpacts.com/rd/p?c=10063... 📄DOI: doi.org/10.1016/j.he...

Alpha-Synuclein Pathophysiology in Neurodegenerative Disorders: A Review Focusing on Molecular Mechanisms and Treatment Advances in Parkinson’S Disease Can we halt Parkinson’s? Review finds α-syn therapies like immunotherapy may slow NDD progression. #ParkinsonsDisease #Synucleinopathies

Can we halt Parkinson’s? Review finds α-syn therapies like immunotherapy may slow NDD progression. #ParkinsonsDisease #Synucleinopathies
www.rimpacts.com/rd/p?c=10069... 📄DOI: doi.org/10.1007/s105...

Direct Oral Anticoagulants or Warfarin in Patients With Left Ventricular Thrombus After St-Elevation Myocardial Infarction: A Pilot Trial and a Prespecified Meta-Analysis of Randomised Trials Can DOACs treat heart clots? Study suggests rivaroxaban may outperform warfarin for LVT resolution. #Anticoagulants #HeartClots

Can DOACs treat heart clots? Study suggests rivaroxaban may outperform warfarin for LVT resolution. #Anticoagulants #HeartClots
www.rimpacts.com/rd/p?c=10070... 📄DOI: doi.org/10.4244/eij-...

Eco-Friendly Synthesis of Core–Shell Ag@Cds Nanoprobes From Sweet Lemon Waste for Selective Fluorescence Detection of Losartan in Biofluids Can fruit waste detect drugs? Study uses AgNPs@CDs from lemon waste to sense losartan. #Nanoprobe #Hypertension

Can fruit waste detect drugs? Study uses AgNPs@CDs from lemon waste to sense losartan. #Nanoprobe #Hypertension
www.rimpacts.com/rd/p?c=10072... 📄DOI: doi.org/10.1016/j.mi...

Design, Synthesis, in Vitro Evaluation, and Molecular Dynamics Simulation Studies of Novel Coumarin-Acetohydrazide Schiff Base Derivatives As Urease Enzyme Inhibitors Can new drugs stop H. pylori? Study finds coumarin-acetohydrazide derivatives potently inhibit urease. #HPylori #UreaseInhibitors

Can new drugs stop H. pylori? Study finds coumarin-acetohydrazide derivatives potently inhibit urease. #HPylori #UreaseInhibitors
www.rimpacts.com/rd/p?c=10079... 📄DOI: doi.org/10.1007/s000...

Natural Products in the Clinical Management of Metabolic Syndrome Can herbs treat MetS? Review finds curcumin & resveratrol show promise for metabolic syndrome. #MetabolicSyndrome #NaturalProducts

Can herbs treat MetS? Review finds curcumin & resveratrol show promise for metabolic syndrome. #MetabolicSyndrome #NaturalProducts
www.rimpacts.com/rd/p?c=10081... 📄DOI: doi.org/10.1007/164_...

Chondrogenic Potential of Pmscs Cultured on Chondroitin Sulfate/ Gelatin-Modified Dbm Scaffold Can scaffolds heal joints? Study finds GCS/DBM scaffold enhances chondrogenesis for osteoarthritis. #Osteoarthritis #TissueEngineering

Can scaffolds heal joints? Study finds GCS/DBM scaffold enhances chondrogenesis for osteoarthritis. #Osteoarthritis #TissueEngineering
www.rimpacts.com/rd/p?c=10082... 📄DOI: doi.org/10.34172/bi....

Human Metapneumovirus (Hmpv) in 2025: Emerging Trends and Insights From Community and Hospital-Based Respiratory Panel Analyses—A Comprehensive Review Is hMPV a big threat? Study finds 6.24% infection rate in ARI patients, urging better diagnostics. #HumanMetapneumovirus #RespiratoryInfections

Is hMPV a big threat? Study finds 6.24% infection rate in ARI patients, urging better diagnostics. #HumanMetapneumovirus #RespiratoryInfections
www.rimpacts.com/rd/p?c=10083... 📄DOI: doi.org/10.1186/s129...

Corrigendum to “Development of Silk Fibroin/Collagen Film Containing Gi-20 Peptide-Loaded Plga Nanoparticles Against Corneal Herpes Simplex Virus-1” [Int. J. Pharm. 669 (2025) 125022](S0378517324012560)(10.1016/J.Ijpharm.2024.125022) Correction: Study funding details updated. #ResearchFunding #Correction

Correction: Study funding details updated. #ResearchFunding #Correction
www.rimpacts.com/rd/p?c=10084... 📄DOI: doi.org/10.1016/j.ij...

Synthesis and Characterization of Amlodipine-Conjugated Gd3+-Citric Acid Peg Dendrimers for Enhanced Cardiac Mri Contrast Can safer MRI agents help hearts? Study finds Gd3+-dendrimer-amlodipine boosts cardiac imaging. #MRIContrast #CardiacImaging

Can safer MRI agents help hearts? Study finds Gd3+-dendrimer-amlodipine boosts cardiac imaging. #MRIContrast #CardiacImaging
www.rimpacts.com/rd/p?c=10084... 📄DOI: doi.org/10.1016/j.mo...

The Reality of Modeling Irritable Bowel Syndrome: Progress and Challenges Can tech improve IBS treatment? Review suggests AI & organ-on-chip enhance drug development. #IrritableBowelSyndrome #AIinMedicine

Can tech improve IBS treatment? Review suggests AI & organ-on-chip enhance drug development. #IrritableBowelSyndrome #AIinMedicine
www.rimpacts.com/rd/p?c=10084... 📄DOI: doi.org/10.1080/1746...

Exploring the Financial Burden of Pediatric Bone Marrow Transplantation: A Cross-Sectional Study From the Caregiver’S Viewpoint How costly is bone marrow transplant? Study finds caregivers face major financial strain. #BoneMarrowTransplant #FinancialBurden

How costly is bone marrow transplant? Study finds caregivers face major financial strain. #BoneMarrowTransplant #FinancialBurden
www.rimpacts.com/rd/p?c=10088... 📄DOI: doi.org/10.1186/s129...

Integrating Cnns and Chemometrics for Analyzing Nir Spectra and Rgb Images in Turmeric Adulterant Detection Can AI spot fake turmeric? Study finds CNN, NIR spectroscopy detect adulterants accurately. #FoodAdulteration #DeepLearning

Can AI spot fake turmeric? Study finds CNN, NIR spectroscopy detect adulterants accurately. #FoodAdulteration #DeepLearning
www.rimpacts.com/rd/p?c=10096... 📄DOI: doi.org/10.1016/j.jf...

The Effects of Peptide If7-Conjugated Dendrimer Loaded With Doxorubicin on Colorectal Cancer Can nanoparticles fight cancer? Study finds G2+DOX+IF7 targets Wnt/β-catenin in CRC cells. #ColorectalCancer #Nanotherapy

Can nanoparticles fight cancer? Study finds G2+DOX+IF7 targets Wnt/β-catenin in CRC cells. #ColorectalCancer #Nanotherapy
www.rimpacts.com/rd/p?c=10096... 📄DOI: doi.org/10.1186/s126...

A Novel Broad-Spectrum Bacteriophage Cocktail Against Methicillin-Resistant Staphylococcus Aureus: Isolation, Characterization, and Therapeutic Potential in a Mastitis Mouse Model Can phages beat MRSA? Study finds bacteriophage cocktail reduces mastitis bacterial load. #BacteriophageTherapy #MRSA

Can phages beat MRSA? Study finds bacteriophage cocktail reduces mastitis bacterial load. #BacteriophageTherapy #MRSA
www.rimpacts.com/rd/p?c=10097... 📄DOI: doi.org/10.1371/jour...

Correction To: Placenta-Specific1 (Plac1) Is a Potential Target for Antibody-Drug Conjugate-Based Prostate Cancer Immunotherapy (Scientific Reports, (2017), 7, 1, (13373), 10.1038/S41598-017-13682-9) Prostate cancer drug fix confirmed? Corrected study shows anti-PLAC1-ADC kills LNCaP cells better than free SN38—IC50 edge via Calcein AM. Research suggests precise targeting. Better therapies ahead? #ProstateCancer #ADCtherapy

Prostate cancer drug fix confirmed? Corrected study shows anti-PLAC1-ADC kills LNCaP cells better than free SN38—IC50 edge via Calcein AM. Research suggests precise targeting. Better therapies ahead? #ProstateCancer #ADCtherapy
www.rimpacts.com/rd/p?c=10098... 📄DOI: doi.org/10.1038/s415...

Carbohydrates-Based (Nano)Catalysts in Multicomponent Reactions: Advances, Limitations and Prospects Sugar catalysts go green? Review spotlights chitosan/alginate nano-catalysts for MCRs—eco-friendly bonds. Research suggests sustainable chem labs. Sweet synthesis? #GreenChemistry #CarbohydrateCatalysts

Sugar catalysts go green? Review spotlights chitosan/alginate nano-catalysts for MCRs—eco-friendly bonds. Research suggests sustainable chem labs. Sweet synthesis? #GreenChemistry #CarbohydrateCatalysts
www.rimpacts.com/rd/p?c=10099... 📄DOI: doi.org/10.1016/j.mo...

Polyhexamethylene Biguanidine Coated Silver Nanoparticles Embedded Into Chitosan Thiourea/Pva Nanofibers As Wound Healing Mats: In Vitro and in Vivo Studies Nano-dressing heals burns fast? Chitosan-Ag/PHMBG nanofibers killed 95% S.aureus/P.aeruginosa—sped wound closure in rats. Study promises infection-free recovery. Burn breakthrough? #BurnWound #NanofiberDressing

Nano-dressing heals burns fast? Chitosan-Ag/PHMBG nanofibers killed 95% S.aureus/P.aeruginosa—sped wound closure in rats. Study promises infection-free recovery. Burn breakthrough? #BurnWound #NanofiberDressing
www.rimpacts.com/rd/p?c=10099... 📄DOI: doi.org/10.1016/j.ca...

🌟 TUMS School of Pharmacy Shines Globally

💊 Ranked 51–75 worldwide in Pharmacy & Pharmaceutical Sciences in the latest Shanghai GRAS — the only Iranian field in the top tier!
🏆 Proudly showcasing Iran’s excellence in pharmaceutical research.

#TUMS #Pharmacy #ShanghaiRanking #MedicalSciences

Development of a Dual-Frequency Sonophoresis for Enhanced Skin Permeability and Efficient Drug Delivery Can ultrasound boost drug delivery? Study finds dual-frequency sonophoresis enhances skin permeation 51-fold. #TransdermalDelivery #Sonophoresis

Can ultrasound boost drug delivery? Study finds dual-frequency sonophoresis enhances skin permeation 51-fold. #TransdermalDelivery #Sonophoresis
www.rimpacts.com/rd/p?c=10096... 📄DOI: doi.org/10.1016/j.ij...