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Cardiovascular Diseases Research Institute

@tumscvdri.bsky.social

Tehran Heart Center #THC | Tehran University of Medical Sciences #TUMS | Advancing cardiovascular #research & #education to enhance global heart health. Join us for the latest updates in #cardiology and #MedicalInnovation. #MedicalResearch

49 Followers  |  417 Following  |  57 Posts  |  Joined: 30.06.2025  |  1.7078

Latest posts by tumscvdri.bsky.social on Bluesky

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Pseudoaneurysms of the Ascending Aorta Following Coronary Artery Bypass Surgery, Presenting as Stroke TEE simultaneous orthogonal long axis and short axis views and MDCT of ascending aorta sagittal view demonstrate two complicated pseudoaneurysm (*) in anterior wall of ascending aorta and intramural ....

#Pseudoaneurysms of the ascending aorta can present as #stroke, revealed by multimodal imaging including TEE and MDCT. Early recognition is vital for timely management. #CABG onlinelibrary.wiley.com/doi/10.1111/...

09.08.2025 06:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The Effect of Sacubitril/Valsartan on Supraventricular and Ventricular Arrhythmias in Patients With Heart Failure Patients undergoing SV therapy had significantly less VTVF events and associated clinical interventions. This effect could lead to less possibility of lethal arrhythmia and sudden cardiac death.

#Sacubitril/Valsartan (SV) therapy significantly reduces ventricular tachycardia (VT) and ventricular fibrillation (VF), and decreases implantable cardioverter-defibrillator interventions in #HeartFailure with reduced ejection fraction patients. #Arrhythmia onlinelibrary.wiley.com/doi/10.1111/....

09.08.2025 06:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Atherogenic Index of Plasma (AIP) as a Long‐Term Prognostic Factor Following CABG: Unveiling Insights From a Large‐Scale Tertiary Center Registry Analysis Background and Aims The role of the atherogenic index of plasma (AIP) in predicting major adverse cerebro-cardiovascular events (MACCE) after coronary artery bypass grafting (CABG) surgery has not b...

Atherogenic Index of Plasma (AIP) predicts key complications after #CABG, helping improve long-term risk assessment.
#Cardiology #AIP #CoronaryArteryDisease onlinelibrary.wiley.com/doi/10.1002/...

05.08.2025 12:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Short- and mid-term outcomes after redo surgical valve replacement - European Journal of Medical Research Background While previous studies have indicated comparable outcomes for redo surgical valve replacement (SVR) and primary SVR, there is limited information regarding the long-term follow-up of these ...

We examined outcomes after redo surgical #ValveReplacement. Good news: results are acceptable, especially for lower-risk patients. We've pinpointed key predictors for better patient care. #RedoSurgery #Mortality #Prognosis #ValveReplacement eurjmedres.biomedcentral.com/articles/10....

05.08.2025 11:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A rare ACTH-secreting #PituitaryAdenoma in a 6-year-old caused Cushing’s disease. Early diagnosis with hormonal tests and brain MRI is vital for effective treatment and preventing complications. Awareness in #pediatric #endocrinology is key. #CushingDisease onlinelibrary.wiley.com/doi/10.1002/...

04.08.2025 08:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Recurrent Cardiovascular Implantable Electronic Device Infection: A Case Report Cardiac implantable electronic devices (CIEDs) are widely utilized to manage various cardiac conditions, including arrhythmias and heart failure. Despite th...

Recurrent infections in a child with a #CardiacImplantableElectronicDevice (CIED) highlight the need for careful device removal and prolonged antibiotic therapy to improve outcomes. #Pacemaker #PediatricCardiology #Artificial #Infection #CaseReport brieflands.com/articles/api...

04.08.2025 08:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Comparative diagnostic accuracy of pre-test clinical probability scores for the risk stratification of patients with suspected pulmonary embolism: a systematic review and Bayesian network meta-analysi... Background The primary evaluation of pulmonary embolism (PE) is complicated by the presence of various pre-test clinical probability scores (pCPS) with different cut-offs, all equally recommended by g...

#PulmonaryEmbolism #Diagnosis #ClinicalScores #EmergencyCare In PE diagnosis, revised Geneva score outperforms Wells for imaging and D-dimer use. Two-tier Wells underperforms. PERC may reduce unnecessary tests but needs more evidence. #RiskAssessment bmcpulmmed.biomedcentral.com/articles/10....

04.08.2025 08:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Effectiveness of body roundness index for the prediction of nonalcoholic fatty liver disease: a systematic review and meta-analysis - Lipids in Health and Disease Background Several anthropometric indices, such as body mass index and waist circumference, have been used as clinical screening tools for the prediction of nonalcoholic fatty liver disease (NAFLD). T...

The #BodyRoundnessIndex (BRI) effectively predicts #NonalcoholicFattyLiverDisease (NAFLD) with good accuracy. This meta-analysis supports BRI as a useful clinical screening tool. #LiverHealth #Prediction lipidworld.biomedcentral.com/articles/10....

03.08.2025 08:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Predicting In‐Hospital Mortality in Patients With Acute Myocardial Infarction: A Comparison of Machine Learning Approaches In this study, we developed and validated machine learning models to predict in-hospital mortality in patients with myocardial infarction undergoing PCI, using data from Tehran Heart Center (2011–202...

Machine learning algorithms predict mortality in patients with AMI, AUC range from 0.8 to 0.9 onlinelibrary.wiley.com/doi/full/10.... #cardiosky

01.04.2025 14:58 β€” πŸ‘ 1    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Stress-Induced Cardiomyopathy Following Kidney Transplant Takotsubo syndrome (TTS), commonly referred to as stress-induced cardiomyopathy, is a reversible type of nonischemic heart failure mimicking acute cor…

Stress-induced #cardiomyopathy (Takotsubo) can occur post-kidney transplant, mimicking acute coronary syndrome but reversible. Early recognition is vital for recovery. #Takotsubo #KidneyTransplant #CaseReport www.sciencedirect.com/science/arti...

03.08.2025 08:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post-Transcatheter Aortic Valve Replacement Antithrombotic Treatment in Non-indicated Patients: Updated Systematic Review and Network Meta-Analysis:

According to a comprehensive network meta-analysis, single antiplatelet therapy (SAPT) is the preferred antithrombotic strategy post-TAVR in patients without an indication for anticoagulation, demonstrating optimal safety without compromising efficacy www.jacc.org/doi/10.1016/...

01.04.2025 06:33 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Preoperative body composition metrics as predictors for... : Annals of Medicine and Surgery ta is scattered and inconsistent for different BC metrics and complications. We aim to evaluate the predictive value of all BC measures reported in the literature regarding CRC surgery outcomes. Meth...

Preoperative #BodyComposition can predict key #complications after #ColorectalCancerr surgery. High visceral fat and #sarcopenia raise risks of complications and readmission. More research is needed to standardize assessment for better patient care. journals.lww.com/annals-of-me...

02.08.2025 07:15 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Incidence and predictors of type 2 diabetes mellitus during 17 years of follow-up in the Golestan Cohort Study - Scientific Reports Scientific Reports - Incidence and predictors of type 2 diabetes mellitus during 17 years of follow-up in the Golestan Cohort Study

17-year #Golestan study: 13.3% developed type 2 #diabetes. #Hypertension, #dyslipidemia, high #BMI, and waist circumference increase risk; smokers showed lower risk. Metabolic and environmental factors drive diabetes. #PublicHealth www.nature.com/articles/s41...

02.08.2025 07:05 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Liver biomarkers as predictors of prognosis in heart failure with preserved ejection fraction: a systematic review and meta-analysis - BMC Cardiovascular Disorders Background Heart failure with preserved ejection fraction (HFpEF) accounts for 50% of heart failure cases, with increasing prevalence due to aging and risk factors such as hypertension and obesity. Li...

#SerumAlbumin predicts better outcomes in #HFpEF patients, while other liver markers have limited value. This simple biomarker can aid risk stratification in #HeartFailure care. #Cardiology #MetaAnalysis bmccardiovascdisord.biomedcentral.com/articles/10....

02.08.2025 06:57 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Suicide and Self-Harm Events With GLP-1 Receptor Agonists This systematic review and meta-analysis evaluates the risk of suicidality and self-harm in randomized, placebo-controlled trials of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in adults wit...

Meta-analysis on GLP-1's and suicide risk:

"our systematic review and meta-analysis does not support an association between GLP-1's and increased risk of adverse psychiatric events, inclusive of suicide completion or attempt, suicidal ideation, and self-harm."
jamanetwork.com/journals/jam...

20.03.2025 11:08 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Clinical Outcomes and Prognostic Implications of TAVR in Patients With Active Cancer: A Meta‐Analysis Clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with active cancer compared to those without cancer.

onlinelibrary.wiley.com/doi/full/10....

10.04.2025 19:38 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The role of bariatric surgery in hypertension control: a systematic review and meta-analysis with extended benefits on metabolic factors - BMC Cardiovascular Disorders Background By 2025, global obesity rates are projected to reach 16% in men and 21% in women, imposing a significant public health burden. Obesity is a major contributor to hypertension (HTN), exacerba...

#MetaAnalysis shows #BariatricSurgery outperforms non-surgical treatments in lowering #BloodPressure and improving metabolic health in obese #hypertensive patients. Roux-en-Y gastric bypass leads the benefits. #Obesity bmccardiovascdisord.biomedcentral.com/articles/10....

29.07.2025 05:57 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Unraveling the link between birth order and blood pressure: insights from a comprehensive systematic review and meta-analysis The objective of the present systematic review was to incorporate previous studies investigating the association of birth order with the risk of systo…

Large #MetaAnalysis finds no significant difference in systolic or diastolic #BloodPressure between firstborns and later-borns. #BirthOrder may not affect blood pressure levels after all. #Epidemiology #PublicHealth www.sciencedirect.com/org/science/...

29.07.2025 05:51 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Assessing differential application of thromboprophylaxis regimes related to risk of pulmonary embolism and mortality in COVID-19 patients through instrumental variable analysis - Scientific Reports Scientific Reports - Assessing differential application of thromboprophylaxis regimes related to risk of pulmonary embolism and mortality in COVID-19 patients through instrumental variable analysis

Study found no clear link between higher Low Molecular Weight Heparin doses and lower #PulmonaryEmbolism in severe #COVID19, but possible lower in-hospital mortality with higher doses. More research needed! #Thrombosis #Heparin www.nature.com/articles/s41...

29.07.2025 05:37 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Global research trends on DPP-4 inhibitors and... : Annals of Medicine and Surgery cular safety and efficacy. This bibliometric analysis aims to provide insights into the global research landscape on DPP-4 inhibitors and cardiovascular outcomes (CVOs). Methods: A bibliometric ana...

Global trends in DPP-4 inhibitor research focus on #CardiovascularOutcomes like #HeartFailure and #AtrialFibrillation in type 2 #diabetes. Leading institutions and authors drive this evolving field. #DPP4Inhibitors journals.lww.com/annals-of-me...

28.07.2025 05:22 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Demographics, Clinical Characteristics, Microbiological Findings, and Risk Factors of 66 Patients with Cardiac Implantable Electronic Devices Infection Cardiac implantable electronic device (CIED) infection is a significant complication associated with implantable cardiac devices, resulting in considerable ...

66 patient data with Cardiac implantable electronic device #infections reveal diagnostic challenges, especially in culture-negative cases. Imaging and clinical judgment are key. #Endocarditis #StaphylococcusAureus #Enterococcus brieflands.com/articles/irc...

28.07.2025 05:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Artificial intelligence in cardiovascular procedures: a... : Annals of Medicine and Surgery ines research trends, key contributors, and emerging themes in AI-driven cardiovascular interventions. Methods: We retrieved relevant publications from the Web of Science Core Collection and analyz...

#AI is rapidly transforming cardiovascular proceduresβ€”from diagnosis to surgery. Our bibliometric study shows booming global research, with top themes like #MachineLearning & #PredictiveModeling. Big potential for improved outcomes! #CardiovascularSurgery journals.lww.com/annals-of-me...

27.07.2025 05:16 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Renal Denervation Effects on Blood Pressure in Resistant and Uncontrolled Hypertension: A Meta‐Analysis of Sham‐Controlled Randomized Clinical Trials Renal denervation (RDN) holds great promise as a treatment for lowering blood pressure in patients with treatment-resistant hypertension. It demonstrates significant improvements in both office and a....

#RenalDenervation lowers office & ambulatory systolic and diastolic #BloodPressure in resistant #hypertension vs. sham, with low risk of serious complications. Promising, but evidence remains limited. #MetaAnalysis #Cardiology @adrianvhernandez.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

27.07.2025 05:06 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Septic shock caused by postpartum acute pancreatitis, a case report and literature review - International Journal of Emergency Medicine Introduction Postpartum acute pancreatitis (PAP) is a rare but potentially life-threatening condition that can occur following childbirth. The incidence of PAP is estimated to be between 1 in 1,000 an...

Rare but life-threatening postpartum #AcutePancreatitis can lead to #SepticShock. Prompt diagnosis and urgent endoscopic retrograde cholangiopancreatography plus surgery are vital. Awareness saves lives. #Gallstones #Sepsis intjem.biomedcentral.com/articles/10....

26.07.2025 08:28 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Fabrication of a multilayer bioabsorbable composite vascular stent utilizing oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers - Scientific Reports Scientific Reports - Fabrication of a multilayer bioabsorbable composite vascular stent utilizing oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers

Multilayer bioabsorbable vascular stent with oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers shows strong mechanics and biocompatibility. Fabricated via #electrospinning and #LaserCutting for advanced cardiovascular care. #Biomaterials #Nanotech www.nature.com/articles/s41...

26.07.2025 08:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Rapidly Growing Second Heart Post-Mitral Valve Replacement With Successful Surgical Treatment:

Rare and dangerous #LeftVentricle pseudoaneurysm after #MitralValveReplacement. Successful surgery highlights importance of quick action. #Cardiology #HeartHealth #Rupture www.jacc.org/doi/10.1016/...

26.07.2025 08:09 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Cardiovascular anomalies in patients with Tessier syndrome: a systematic review - European Journal of Pediatrics Tessier clefts are skeletal and soft tissue abnormalities of a neonate’s facial structures. They could be classified as syndromic and non-syndromic clefts, which can be attributed to disruptions in fe...

Our systematic review highlights a critical oversight in #cleft care:While #Tessier clefts dominate attention for their facial impact,cardiovascular anomalies can be life-threatening. #Cardiac screening must precede cosmetic surgery. #Pediatrics #CongenitalHeart
link.springer.com/article/10.1...

19.07.2025 09:28 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Prognostic Value of Cardiac Biomarkers in Patients Undergoing On-Pump Coronary Artery Bypass Grafting: A Cohort Study in An Iranian Population Reza Ebadi, M.D., Younes Nozari, M.D., Mina Pashang, M.Sc., Vanoushe Azimi Pirsaraei, M.D., Hamid Khederlou, M.D.. J Chest Surg 2025;58:99-106. https://doi.org/10.5090/jcs.24.073

Pre/post-op levels of #hsTnT & #CKMB predict 1-year major adverse cardiovascular events in on-pump #CABG patients. Crucial for risk assessment & improving outcomes. #Cardiology #CardiacBiomarkers #Troponin www.jchestsurg.org/journal/view...

23.07.2025 06:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Incidence of secondary pericardial effusions associated with different etiologies: a comprehensive review of literature - Journal of Cardiothoracic Surgery Pericardial effusion is a relatively common complication associated with inflammatory and non-inflammatory diseases. The primary etiology of this condition could be considered when choosing therapeuti...

Secondary #PericardialEffusion: #causes, #diagnosis, and #treatment options explained. Know when to observe and when urgent intervention is needed. #Cardiology #MedicalReview cardiothoracicsurgery.biomedcentral.com/articles/10....

23.07.2025 06:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Safety, efficacy, and cardiovascular benefits of combination therapy with SGLT-2 inhibitors and GLP-1 receptor agonists in patients with diabetes mellitus: a systematic review and meta-analysis of ran... Background The potential benefits and risks of combination therapy with sodium-glucose co-transporter-2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) versus monotherap...

#CombinationTherapy with SGLT-2 inhibitors and GLP-1 receptor agonists improves heart and #MetabolicOutcomes in type 2 #diabetes, reducing #HeartFailure #hospitalizations and major #CardiovascularEvents, with some increased GI side effects. #Diabetes dmsjournal.biomedcentral.com/articles/10....

21.07.2025 06:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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