Benoit Miotto's Avatar

Benoit Miotto

@benoitmiotto.bsky.social

PI at Institut Cochin. CNRS, INSERM u1016, University Paris Cité. Focus on Epigenetics, DNA replication & diseases.

512 Followers  |  246 Following  |  13 Posts  |  Joined: 08.05.2024  |  1.8703

Latest posts by benoitmiotto.bsky.social on Bluesky

C’est parti pour le challenge lancé par l'association 2500 Voix : cumuler 384000 km pour envoyer les cancers pédiatriques sur la lune ! Rejoignez-les sur Strava, Insta ou Facebook. A vos baskets !

2500voix.org

07.02.2026 11:31 — 👍 0    🔁 0    💬 0    📌 0

Upcoming seminar by Regis Tournebize,: How Science Adapts to a Changing Society at Institut Cochin, Monday 26 January 2026 at 9:00. More info

18.01.2026 11:19 — 👍 0    🔁 1    💬 0    📌 0
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer Targeting the chromatin-modifying activities of the SUV4-20H enzyme family offers a promising epigenetic strategy to enhance the potency of the topoisomerase-2 poison etoposide in prostate cancer ther...

Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals.org/cancerres/ar...

17.01.2026 23:58 — 👍 2    🔁 0    💬 0    📌 0

Last few days to apply for this PhD project in our lab. Mix of biochemistry and structural biology, DNA replication and ubiquitin signalling. Get in touch if interested. Full application through official university portal. Deadline on 27th of November!

22.11.2025 08:44 — 👍 7    🔁 10    💬 0    📌 0
Post image

🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨

#PhD #3DGenome

15.11.2025 09:52 — 👍 36    🔁 37    💬 0    📌 3
Circulating miR-16-5p, miR-92a-3p and miR-451a are biomarkers of lung cancer in Tunisian patients | BMC Cancer

😍 rdcu.be/eNgy2

29.10.2025 12:17 — 👍 0    🔁 0    💬 0    📌 0

Very Nice 👏👏👏

28.10.2025 16:49 — 👍 0    🔁 0    💬 0    📌 0

😍 congratulations Hana & al.

28.10.2025 16:45 — 👍 1    🔁 0    💬 1    📌 0
Login Page

📌New paper📌
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals-org.insb.bib.cnrs.fr/cancerres/ar...

23.10.2025 14:07 — 👍 1    🔁 0    💬 0    📌 0

Join us for this fantastic meeting in the heart of Paris with an amazing line up of dendritic cell and macrophage experts! And 2 Keynote speakers: Yasmine Belkaid and Dan Littman 🤩

18.10.2025 13:06 — 👍 1    🔁 2    💬 0    📌 0
Preview
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!

Come join us in Geneva for everything epigenetics and gene regulation. It will be a great meeting! Please repost!
www.keystonesymposia.org/conferences/...

17.10.2025 14:36 — 👍 42    🔁 27    💬 1    📌 0

Consultez le programme complet de la #FDS2025 à l' @institutcochin.bsky.social :https://institutcochin.fr/lanimation/science-societe/fete-science/fete-science-2025

17.09.2025 16:31 — 👍 1    🔁 3    💬 0    📌 0

RAD51 and Cancer. A must read by Bernard Lopez in Oncogene.

04.10.2025 12:28 — 👍 3    🔁 2    💬 0    📌 0
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer Abstract. Commonly used in cancer therapy, topoisomerase II (TOP2) poisons are designed to stabilize the normally transient DNA TOP2 cleavage complexes in chromatin, leading to deleterious DNA double-...

Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals.org/cancerres/ar...

03.10.2025 19:21 — 👍 1    🔁 0    💬 0    📌 0
Post image

Pleased to announce launching Institut Cochin Foundation, on Sept. 18 at 6 p.m., upon registration, either in the Rosalind Franklin room, 22 rue Méchain, Paris or via video conference: presentation of @institutcochin.bsky.social, meet researchers and call for donations-thanks for your support!

06.09.2025 06:45 — 👍 12    🔁 13    💬 0    📌 2
Titre : Aide à mourir : quelle liberté de choix pour les plus fragiles ?

Un homme, carnet à la main, s’adresse à un patiente alité.
- Alors… dans le cadre de notre hôpital en ruine, vous préférez :
A) Être abandonné à votre souffrance qui, faute de moyens et de volonté politique, ne pourra absolument pas être prise en charge...
ou
B) mourir ?

Titre : Aide à mourir : quelle liberté de choix pour les plus fragiles ? Un homme, carnet à la main, s’adresse à un patiente alité. - Alors… dans le cadre de notre hôpital en ruine, vous préférez : A) Être abandonné à votre souffrance qui, faute de moyens et de volonté politique, ne pourra absolument pas être prise en charge... ou B) mourir ?

Pour ma part, j'ai toujours été pour le droit de mourir dans la dignité.

Mais il faut entendre les soignants, les malades et les personnes handicapées qui alertent : sans un système de santé capable d’accompagner dignement, la liberté de choisir sa fin existe t-elle réellement ?

27.05.2025 10:36 — 👍 881    🔁 401    💬 23    📌 16

Targeting SUV4-20H epigenetic enzymes as therapeutic strategy for enhancing topoisomerase II poisoning in prostate cancer https://www.biorxiv.org/content/10.1101/2025.03.11.642623v1

14.03.2025 15:50 — 👍 0    🔁 1    💬 0    📌 0

😍😍

18.03.2025 07:31 — 👍 0    🔁 0    💬 0    📌 0
Post image

🌊 Nestled in the heart of the Calanques of Marseille, the IBDM offers an exceptional work environment 🌿✨

🔬 Conduct research with a sea view
🌞 Work in an inspiring natural setting
🌍 Combine scientific excellence with quality of life

Join us as a Group Leader: https://tinyurl.com/ukf2rn2x

14.03.2025 09:02 — 👍 32    🔁 32    💬 1    📌 0
Preview
Mechanism for local attenuation of DNA replication at double-strand breaks - Nature DNA double-strand breaks induce local genome maintenance and inhibition of replication initiation at nearby topologically associating domains without affecting global DNA synthesis.

Nature research paper: Mechanism for local attenuation of DNA replication at double-strand breaks

https://go.nature.com/4k8AdCX

20.02.2025 18:57 — 👍 18    🔁 5    💬 0    📌 0

Interested in exploring epigenetic cell memory? Join us!! 6 PhD and postdoc positions available in our new center, EpiC.

12.02.2025 23:11 — 👍 18    🔁 12    💬 0    📌 1

Effectivement. Une belle après midi avec des élèves très curieux.

06.02.2025 20:48 — 👍 1    🔁 1    💬 0    📌 0
Institut Cochin

Institut Cochin

The 4th of February is commemorated as World Cancer Day.
Cancer research is a strong focus of the Institut Cochin, with 15 teams involved in the studying molecular and cellular mechanisms that favor the development of cancers. A major aim of our research is to develop novel therapies.

04.02.2025 14:45 — 👍 4    🔁 3    💬 0    📌 0
Post image

📢 We are recruiting group leaders!

We seek researchers who address fundamental questions in biology, including the development, the function, and the dynamics of complex biological systems.

APPLY before March 30th 2025 👉 www.ibdm.univ-amu.fr/we-are-recru...

#ScienceCareers #Marseille

21.01.2025 08:58 — 👍 39    🔁 34    💬 0    📌 4
Post image

We are looking for a #Postdoc to join our team to work on a funded project by La Ligue investigating the role of #gut permeability as a cause of #cancer with #age. 🐟🐟🐟
#zebrafish #telomerase #microbiome DEADLINE: 29/Jan/2025
Please help us spread the word! 🙏

18.01.2025 11:50 — 👍 18    🔁 14    💬 0    📌 2

📣Paris-Munich Epigenetics (Workshop and Symposium)

📆 April 9-11, 2025
📍Buffon amphitheater, Université Paris Cité, France

Free of charge but registration is mandatory.

Deadline for abstract submissions and workshop applications is tomorrow

🔗 urls.fr/1VRiOh

14.01.2025 09:17 — 👍 3    🔁 3    💬 0    📌 0
Post image

📢 #Yeast2025 News!
Registration and abstract submission are NOW OPEN!
Join us at the 32nd ICYGMB
📅 Save the Date: 21-24 July 2025
📍 Location: Paris @sorbonne-universite.fr
🔗 Submit: premc.org/yeast2025/su...
🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...

14.01.2025 07:28 — 👍 34    🔁 28    💬 2    📌 2
Post image

Please RT. Join the sixth edition of our Training Unit @institut_curie
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...

04.01.2025 11:30 — 👍 12    🔁 11    💬 0    📌 1

Bravo Bertrand 🎉

03.01.2025 22:22 — 👍 2    🔁 0    💬 0    📌 0

Congrats Kasia & team 🎉

03.01.2025 22:06 — 👍 1    🔁 0    💬 1    📌 0

@benoitmiotto is following 19 prominent accounts