Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
Nature Communications - Breast cancer cells interact with neighbouring adipocytes, but the mechanisms are not fully understood. Here, the authors show that triple-negative breast cancer (TNBC)...
New work from stellar scientists Jeremy Williams and Roman Camarda. Many contributors including the amazing Zena Werb and Atul Butte
Work explores how breast cancer cells interact directly with adipocytes via gap junctions, leading to lipid release.
@ctbatucsf.bsky.social @ucsfcancer.bsky.social
20.08.2025 10:19 β π 15 π 11 π¬ 0 π 1
I'm happy people can read the final version of this paper! See what happens when we detach heterochromatin from the nuclear periphery in mouse stem cells:
23.07.2025 01:21 β π 5 π 1 π¬ 0 π 0
Primary cilia and BBS4 are required for postnatal pituitary development
Primary cilia orchestrate several signaling pathways, and their disruption results in pleiotropic disorders called ciliopathies. Bardet Beidl syndrome (BBS), one such ciliopathy, provides insights int...
βΌοΈπ¨Preprint alert! π¨βΌοΈ
Excited to have some of my first works as a postdoc, and first corresponding author (!!), on biorxiv! This was a fun side quest of a project marrying a few things I deeply love, development, cilia, and hormones in the pituitary! Happy reading!
www.biorxiv.org/content/10.1...
19.07.2025 17:58 β π 24 π 9 π¬ 1 π 2
Thank you, Dagmar!!!
07.06.2025 21:39 β π 0 π 0 π¬ 0 π 0
Congratulations, @semilc.bsky.social! Are you interested in the fascinating world of motile cilia? Consider coming to this lab to explore this awesome biology!
06.06.2025 17:35 β π 6 π 2 π¬ 0 π 0
Thanks all - I can't wait to start!
06.06.2025 14:19 β π 0 π 0 π¬ 0 π 0
Thanks Andrei!
06.06.2025 14:16 β π 0 π 0 π¬ 0 π 0
CTB welcomes new Assistant Professor Semil Choksi @semilc.bsky.social to the department! The Choksi Lab will study how airway stem cells generate multiciliated cells - and how this process goes wrong in respiratory disease. His lab is opening this August. Visit choksilab.org to learn more!
05.06.2025 23:07 β π 18 π 4 π¬ 2 π 0
We are thrilled that @semilc.bsky.social and the Choksi Lab will be part of our RMB community! π
05.06.2025 14:59 β π 3 π 2 π¬ 0 π 0
Circular lab logo consisting of a ball of cells labeled with cyan nuclei and red cilia, surrounded by a white circle and the text Choksi Lab and UCSF. The 'o' in Choksi is a schematic of a multiciliated cell.
I'm thrilled to announce that my lab is opening this August in the Department of Cell & Tissue Biology @ UCSF!
We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!
05.06.2025 14:29 β π 55 π 5 π¬ 11 π 3
UCSF, like all UC campuses, announced an immediate hiring freeze today. UCSF is the second largest employer in the city. There will be wide ripple effects in the Bay Area and beyond, including the future of biotech and pharma in the area. π§ͺ
20.03.2025 04:07 β π 74 π 38 π¬ 2 π 0
2025 Fibronectin, Integrins and Related Molecules Conference GRC
The 2025 Gordon Research Conference on Fibronectin, Integrins and Related Molecules will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
A reminder to colleagues interested in Cell-Matrix adhesion & anything ECM related that registration is now open for the Fibronectin, Integrins & related molecules Gordon Research Conference. Incredible list speakers! incredible location! it will π₯ π₯ π₯ Please join us! www.grc.org/fibronectin-...
22.01.2025 04:54 β π 26 π 23 π¬ 0 π 4
2025 Cilia, Mucus and Mucociliary Interactions (GRS) Seminar GRC
The 2025 Gordon Research Seminar on Cilia, Mucus and Mucociliary Interactions (GRS) will be held in Pomona, California. Apply today to reserve your spot.
Are you a trainee interested in cilia? Or mucus? Or mucocliloary interactions? Register for the GRS (www.grc.org/cilia-mucus-...)! We are selecting talks for the cilia session soon, so submit your abstracts asap to be considered!
03.01.2025 23:17 β π 4 π 2 π¬ 0 π 0
2025 Cilia, Mucus and Mucociliary Interactions (GRS) Seminar GRC
The 2025 Gordon Research Seminar on Cilia, Mucus and Mucociliary Interactions (GRS) will be held in Pomona, California. Apply today to reserve your spot.
Are you a trainee interested in cilia? Or mucus? Or mucocliloary interactions? Register for the GRS (www.grc.org/cilia-mucus-...)! We are selecting talks for the cilia session soon, so submit your abstracts asap to be considered!
03.01.2025 23:17 β π 4 π 2 π¬ 0 π 0
Delighted to share our new preprint on the cell biology and genome of Stentor pyriformis, a giant ciliate that maintains Chlorella endosymbionts in surface-associated microtubule baskets.
www.biorxiv.org/content/10.1...
21.12.2024 20:26 β π 282 π 75 π¬ 12 π 7
Cilia alert! Stoked for our new paper in Dev. Cell! Our cross-linking mass spec interactome for motile cilia provides some cool new insights into motile ciliopathy. Helmed by @computingcaitie.bsky.social, read her fantastic Bluetorial below (π)!
www.cell.com/developmenta...
16.12.2024 16:10 β π 38 π 10 π¬ 0 π 1
I am excited to share some of my PhD work on the motile cilia interactome revealed by XL/MS with @jbwallingford.bsky.social @edwardmarcotte.bsky.social Ophelia Papoulas, Chanjae Lee, David Taylor, and @builab.bsky.social www.cell.com/developmenta...
16.12.2024 14:44 β π 67 π 18 π¬ 4 π 5
Super excited to announce my new lab at the University of Michigan opening Jan 2025! πWeβll study how cells work together to shape the GI tract, with ties to regeneration & disease.
Hiring at all levelsβesp. a research tech to help launch the lab! Info: huyckelab.org
#DevBio #CellBio #Hiring
13.12.2024 17:09 β π 82 π 22 π¬ 12 π 1
Graphical abstract of the study
Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)
26.11.2024 15:49 β π 159 π 50 π¬ 15 π 3
Would love to be added, thanks!
21.11.2024 21:36 β π 1 π 0 π¬ 0 π 0
This just out from grad student Samantha Bromley-Coolidge with help from Regis University undergrad Diego Iruegas. By the way, Regis has an awesome neuroscience program. If one of their students applies to your grad program, give them a close look!
authors.elsevier.com/a/1k7nr14Yy4...
20.11.2024 13:35 β π 13 π 5 π¬ 1 π 0
For anything stem cell and pluripotency-related: go.bsky.app/UTW4d7b
20.11.2024 05:44 β π 13 π 9 π¬ 1 π 0
Immunofluorescence staining of airway organoid, stained for cilia (red) and a motile cilia transcription factor (cyan).
Check out this airway organoid stained for cilia (red) and a transcription factor, FOXJ1 (cyan), dedicated to generating motile cilia. This organoid was grown from mouse airway stem cells using a protocol developed by Brigid Hogan's lab (Rock et al., PNAS 2009).
19.11.2024 18:16 β π 7 π 1 π¬ 0 π 0
CSD PhD student at CU Anschutz | NSF GRFP Fellow
Advancing health through excellence in patient care, education, and discovery.
I used to do science. I still do, but I used to, too. // Associate Professor at CU-Anschutz, Peds Dev Bio // Brain development, cell fate, oligodendrocytes, Sonic hedgehog, Notch // New Mexican // Chicano // he/him
PhD student studying nuclear lamin structure/function in the Buchwalter lab @UCSF. Fan of cell type-specific bio, the endoplasmic reticulum, all things proteostasis, and Karl the Fog.
Developmental geneticist who studies the cellular basis of mammalian morphogenesis and how it goes wrong in congenital disease.
We study stem cells- germline stem cells and intestinal stem cells- in different organisms to understand conserved mechanisms that regulate their behavior!
Associate Prof. @UCSF Dept. of Anatomy & Helen Diller Family Comprehensive Cancer Center | My lab studies lysosomes, autophagy, metabolism and pancreatic cancer
visit us at : rushikapereralab.com
Professor, Department of Bioengineering and Therapeutic Sciences, Director, Institute for Human Genetics, UCSF
Sharing research, creative activities and scholarship of students and faculty from the department of biology at San Francisco State University. This is our Official Account.
https://biology.sfsu.edu/
The Institute for Human Genetics (IHG) is the hub for genetics/genomics research, technologies, industry partnerships, training, and education at UCSF.
Assistant Professor at #CVRI @UCSF studying immune-parenchymal cell crosstalk and its impact on tissue function, with special focus in the β€.
Molecular logic of complex cell behaviors.
Orion Weiner's lab at UCSF. Account run by lab members.
#CellMigration #CellPolarity #Mechanics #OptoTools
weinerlab.com
Cell and Tissue Biology at UCSF studies fundamental cellular and molecular mechanisms of development, stem cells, regeneration, and disease
Professor of Art History, Hunter College & CUNY Graduate Center. I look at things and then write about them.
Author of Van Gogh and the End of Nature, from Yale University Press: https://yalebooks.yale.edu/book/9780300274363/van-g
Current postdoc in Wallace Marshall Lab at UCSFπ¦ π | PhD at UCSD Chemistry π§ͺβ±οΈ | BS at UCSB Physicsπ¬ π
π²π½π²π½π²π½
Hoping to stay in academia if science and education surviveπ€π»so I can think and talk about stochasticity, entropy and geometry in cells
Professor at UCSF. Physical cell biologist exploring life. Cell size, shape and division. Cytoplasm. Fungi. Views are my own. π
metabolism + chromatin biologist #chroMetab lab, GI medonc @columbiacancer and dad | πͺπΈπ΅πΎπ¦π·πΊπΈ | @Schvartzman_JM | @schvartzman.bsky.com