Xavier

Altered Mental Status and Falls When Gabapentinoid and Other Psychoactive Medications Are Coprescrib | Docwire News A study assessed the association of coprescribing gabapentinoids and other psychoactive medications with altered mental status and falls in kidney disease.

Is coprescription of gabapentinoids with other psychoactive medications associated with altered mental status and falls? #nephrology #dialysis #gabapentinoid #psychoactivemedication

Their presentation was great and fun to see. Congrats to the winners.

Reversible glomerular thrombotic microangiopathy associated with nintedanib in a kidney transplant recipient We present the case of a 69-year-old male patient non sensitized against HLA who underwent a first kidney transplant after diabetic nephropathy. The patient was also diagnosed with idiopathic pulmonar...

Reversible glomerular thrombotic microangiopathy associated with nintedanib in a kidney transplant recipient
#nephsky
www.kireports.org/article/S246...

Safety and Effectiveness of Nirmatrelvir-Ritonavir in Patients With Advanced Kidney Dysfunction and COVID-19 Nirmatrelvir-ritonavir prevents COVID-19 hospitalization among high-risk adults, but safety concerns limit its use in advanced kidney dysfunction. This study examined safety and effectiveness outcomes...

Paxlovid in advanced CKD, matched study with VA data in @ajkd.bsky.social

www.ajkd.org/article/S027...

cc @christosargyrop.bsky.social - validates our approach 😎

#COVID #NephSky

📣Calling early career scientists, trainees, and junior faculty!

The ASN Journal Portfolio’s Junior Associate Editor Program is your chance to dive into editorial work with JASN, CJASN, and Kidney360. Review manuscripts, get mentored, sharpen your skills, and gain recognition.

🔗 bit.ly/3DZJ75B

Does anyone remember seeing a visual abstract on Sodium Zirconium and edema/sodium load? #AskRenal

Chloride depletion alkalosis (as opposed to what was previously called 'contraction alkalosis') #Nephpearls #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/22223876/

I am "CONVINCE"D that #hemodiafiltration will overcome #incrementalhemodialysis in the @nephmadness.bsky.social match on the first round. you will be lost if you chose #incrementalHD #trashtalk #nephmadness or may be the #blueribbonfail are not yet "CONVINVE"D !!

visual abstract of NOSTONE and bone density from Hector

So @danfuster.bsky.social and colleagues seem to find HCTZ doesn’t work for anything!

In a post hoc analysis of NOSTONE (where CT scans were done in all & repurposed for calculating bone density) HCTZ doesn’t increase it vs placebo

journals.lww.com/cjasn/pages/... in @asnpublications.bsky.social

The @isn-india.bsky.social Journal Club TODAY‼️
📅 When: 19 March 2025 | 08:00 – 09:00 PM IST
📌 Topic: ISN Journal Club – March 2025 - Obinutuzumab in Lupus Nephritis
🔗 Join here: us02web.zoom.us/j/8949743288...
🔑 Passcode: 647870
We look forward to your enthusiastic participation and engagement!

Kidney immunology, not for the faint hearted.

Rapid review of lupus nephritis pathogenesis with the fellows today.

On it

I think this is where I first learned about it.

It turns out, that under the right conditions, carbonyl groups form on MPO. Hydralazine actually ATTACHES to these carbonyl groups, probably modifying the MPO conformation and inducing a neo-antigen, which eventually causes the formation of anti-MPO IgM!

Is “stone camp” still a thing? And how do I get invited? #AskRenal

COL4A5 Intronic Variants at Third to Fifth Nucleotides Cause Alport Syndrome pubmed.ncbi.nlm.nih.gov/39990911/

Non-nephrology related sketch tonight.
Ink and marker sketch of our ancestral home in Cebu, which was torn down last year.
#artsky

Acute kidney injury induced by snakebites in pediatric patients - Pediatric Nephrology Background Snakebites are a significant public health problem worldwide, with a global prevalence estimated 2.7 million envenomings and 81,000 to 138,000 deaths annually. Acute kidney injury (AKI) is ...

ACE inhibitors are not nephrotoxic - but 🐍 snakebite from Bothrops spp can cause AKI in kids

link.springer.com/article/10.1...

In @ped-neph.bsky.social

Though it seems not always mediated by hypotension

#NephSky

Most SEs from steroids are longer term and cumulative, aside from infection. I don’t know of many folks that would rx a CNI first.

Steroid if it’s their first or second go, if frequently relapsing go next to CNI, then if breaking through CNI and prednisone it’s RTX

Cover art of a kidney shaped with flowers

Beautiful cover art on the latest issue of @ndt-era.bsky.social @hjanders.bsky.social

From @nephgirlsketch.bsky.social of course!

academic.oup.com/ndt/issue

Do you have any particular concerns for steroid-related side effects? Or do you always chose steroids as first line?

For minimal change disease in adults. Do you always go for steroid as first line? Or do you consider other alternatives (MMF, CNI)? And if so, what are those scenarios? #askRenal

RN charting that a child hates our guts

This one goes out to all my fans

When AIN recurs after a run with steroids. Do people go for MMF? Do you see any positive results with this?

Complement C5a and C5a receptor 1 mediates glomerular damage in focal segmental glomerulosclerosis Clinical data and animal models have provided compelling evidence supporting the pathogenic role of complement activation in the progression of focal …

Complement C5a and C5a receptor 1 mediates glomerular damage in focal segmental glomerulosclerosis
#nephsky
www.sciencedirect.com/science/arti...

NKF Statement on Mass Staff Terminations at HHS

Good on @kidney.org NKF on putting out a clear statement on this issue

www.kidney.org/press-room/n...

#NephSky

Clearing my driveway

Massachusetts remains covered in snow and ice