Bjørn Panyella Pedersen

PIN auxin transporters facilitate polar transport of synthetic phenoxyacetic acid herbicides | Plantae Synthetic herbicides are widely used in agriculture to control weeds, often by targeting the physiological pathways regulated by auxins, plant hormones that induce root growth and development.

Plant Science Research Weekly -- PIN auxin transporters facilitate polar transport of synthetic phenoxyacetic acid herbicides (Nature Plants) @lukas-schulz.bsky.social‬ @uhammes.bsky.social‬ @bjornppedersen.bsky.social‬
(Summary by Jerry González Cantoral @phytojerry.bsky.social)

View over central Aarhus from a rooftop garden.

A beautiful time of year to visit Denmark, and always a pleasure to be at @au.dk looking very closely at proteins in the Physics Dept basement, and meeting @bjornppedersen.bsky.social and his group.

Just had our 2025 Lab Retreat 🥳. Great science🌱 and interactions 🐛🐝 at Aarhus Harbour🏊‍♀️🛥️ in the nice weather🌞.

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Funded by @erc.europa.eu @novo-nordisk.bsky.social @scholarsatrisk.bsky.social

@molbiolau.bsky.social

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🔬We now understand more about sugar transport and Sugar Transport Proteins, and the results are a next step towards improved pathogen resistance🐛🐜 and energy utilization in agriculture.🌱🌽🌾

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Ultimately we show that we can swap the affinity of fructose and glucose by moving a single methyl group!🤓

This highlights that very minute structural differences that manifest during transport are sufficient to modify transport selectivity.🤯

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👀 relevant for transporter aficionados, we have tested 3 different methodologies to derive apparent affinities (Km) and show that biophysical parameters are highly dependent on protein environment and methodology..
If you compare transport between protein isoforms and methodologies ⚠️BEWARE⚠️

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this is relevant because the main sugar derived from photosynthesis is sucrose🍭 which is equal parts glucose🍬 and fructose 🍡.

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🍬 bite-sized breakdown:

🧑‍🔬 We looked into the mechanics of sugar transport proteins STP6 and STP10. Turns out that despite having a virtually identical binding site, STP6 can transport fructose and glucose, while STP10 remain highly selective for glucose.

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💎💎💎💎 💎💎💎💎
sitting drop membrane protein CRYSTALS 💓
Look at that packing..💖

🚀 Check out our latest paper on the selectivity of sugar transport in plants👇
Amazing work initiated by ⭐Laust Bavnhøj and spearheaded by 💫Camilla Andersen:
www.pnas.org/doi/10.1073/...
Also
💎💎💎💎 CRYSTALS💎💎💎💎

Dear all,

I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!

Dear al,
check out our latest paper with @uhammes.bsky.social .
A great collaborative effort by Lukas and Lam!!

detergent/lipid/protein samples sometimes give us circular crystals. Generally worse than 20 Å diffraction, and impossible to optimize.
normally 6-fold symmetry in the diffraction pattern.

DLS safety training. At least I'll get this one right..😂

⭐8 days left to apply for 👇 postdoc position ⭐
and join an international group of great people😊

Congratulations to @iriskalen.bsky.social. It was a great defense!⭐ A pleasure to participate.

Postdoctoral position in biophysical and structural characterization of sugar and hormone transport, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - Protein Science, Aarhus University

Another 👇opening for a postdoc🚨.
Focus: Structural biology, membrane proteins, biophysics, sugar and hormone transport in plants☘️🔬👩‍🔬🧪
We are recruiting:
- Deadline 28. Feb 2025.
- 2(+2) year position.
- Details and application link: tinyurl.com/yc43bhzs
- PM for questions
Please repost 💚

Center Administrator for Center for Active Transport of Plant Hormones (Plant-PATH) - Ledig stilling på Aarhus Universitet Ledig stilling ved Institut for Molekylærbiologi og Genetik, Aarhus Universitet

🌱 We're hiring! Join our new ⭐Center of Excellence⭐, Plant-PATH, as Center Administrator and help us drive basic research in plant molecular biology🌱.

www.au.dk/om/stillinge...
#Science #dkforsk #dkscience #dkvid #JobOpening #Research

A great but also sad day.😁

Kien Lam Ung; My ⭐️amazing ⭐️postdoc for the last 4 years, now starting up his own research group in Toulouse. I am sure they will do very well. ⭐️🏅
Best of Luck.💜

PhD opportunities (yes, plural!)

We will launch a center of excellence “Plat-PATH” with @bjornppedersen.bsky.social this summer. We have an opening for some PhD students to work on plant hormone transporter mechanism.

- Details and application link: tinyurl.com/44hf9zkd
Please repost 💚

Interested in membrane proteins, biophysics, structures and hormone transport in plants?☘️🔬👩‍🔬🧪
Our new Plant-PATH center is launching soon, and we are looking for 1-2 PhD students to join from day 1.⭐
- Deadline 1. Feb 2025.
- Details and application link: tinyurl.com/44hf9zkd
Please repost 💚

Welp.. I guess that's it then😂. I'll be back in the office Jan 6th.🎄

a cartoon says hey everybody an old man 's talking while bart simpson looks on ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

Bluetorial: Light and Life: The incredible life of Lubert Stryer

I described my involvement with Lubert Stryer and how it led to one of the great opportunities of my life, taking over his textbook. Today, I detail his truly incredible life story.

Four days left for our open position for a postdoc in beautiful Aarhus/Denmark👇👇. If you are interested in structural biology and membrane protein transport⭐ I hope you apply. A fantastic group. Here seen in the wild at our last lab retreat😊😊

Postdoctoral position in biophysical and structural characterization of auxin transport, Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - Protein Science, Aarhus University

Interested in structural biology, membrane proteins, biophysics and working onto understand hormone transport in plants?☘️🔬👩‍🔬🧪
We are recruiting a postdoc:
- Deadline 20. Dec 2024.
- 2(+2) year position.
- Details and application link: tinyurl.com/y7vnewen
- PM for questions
Please repost 💚

Great news🥳. We just got a 1-year SARU fellowship to support a postdoc in the group.
🙏Thanks to Scholars at Risk - Denmark Section.🇩🇰🇺🇦

the SARU fellowship is also supported by Novo Nordisk Fonden, Villum Fonden, and @carlsbergfondet.dk

Do you need a starting pack of researcher working on intrinsically disordered proteins?

Well, you might head over to @idpseminars.bsky.social and hit followers.

Tw***** was important for the birth of IDPseminars and for spreading the word. It would be cool to re-kindle that community here.

Postdoctoral position in biophysical and structural characterization of auxin transport, Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - Protein Science, Aarhus University

Interested in structural biology, membrane proteins, biophysics and working onto understand hormone transport in plants?☘️🔬👩‍🔬🧪
We are recruiting a postdoc:
- Deadline 20. Dec 2024.
- 2(+2) year position.
- Details and application link: tinyurl.com/y7vnewen
- PM for questions
Please repost 💚

Funded by the Danish Council for Independent Research, the Carlsberg foundation, the ERC and the Deutsche Forschungsgemeinschaft. 💰
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