V

Thank you, New York City. Together we made history.

Now let’s get to work.

transition2025.com

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

panel 1: fizz sitting at his computer. a voice comes from offscreen, but it's barely understandable: "can you fo-d th- la--dry t--i--" fizz presses the spacebar, pauses what he was doing and looks back: "wh-sorry what was that?" panel 2: the voice retries, but even quieter : "i said ca- yo- --ld t-- la----" fizz turns around in his chair, smiling nervously : "...sorry i-i still didn't understand..." panel 3: the voice goes "....." fizz, sweating, asks hesitantly : "...just a bit louder please?" panel 4: the voice sighs : "nevermind." fizz looks away with a sad expression.

auditory processing disorder 🔇

#furryart #comic #dogwithajob

That makes sense, in that case you’re probably right when it comes to these platforms lol, I’ve been more on tt than here lately

I Can Be With You, by Max Levinton 8 track album

maxlevinton.bandcamp.com/album/i-can-...
bandcamp friday again? no problem !

first day of school

It’s not that it’s the same at all, tbh the problem comes in IMO when they start saying some shit like “clanker lover” and “clanka” and shit. It’s whatever by itself but people are making it way worse than it should be. And it’s only white ppl on tt I’ve seen doing shit like that

In 1900, 31% of all deaths were children under the age of 5. Today it’s 0.7%. Vaccines, medications, and modern science are the reason why. Trust the science, it’s been proven to work safely and efficiently time and time again.

A Dark Money Group Is Secretly Funding High-Profile Democratic Influencers An initiative aimed at boosting Democrats online offers influencers up to $8,000 a month to push the party line. All they have to do is keep it secret—and agree to restrictions on their content.

David Pakman going from GamerGate “it’s about ethics in games journalism” moron to accepting dark money to spew DNC-approved talking points in his “journalism” is SO FUCKING FUNNY www.wired.com/story/dark-m...

Key Points Question What was the global impact of COVID-19 vaccinations on deaths during the 2020-2024 period? Findings This comparative effectiveness study found that COVID-19 vaccinations averted 2.5 million deaths during 2020-2024 (sensitivity range estimates, 1.4-4.0 million) and saved 15 million life-years (sensitivity range estimates, 7-24 million life-years). The estimated benefits had a steep age gradient. Meaning COVID-19 vaccinations had a substantial benefit on global mortality during 2020-2024, but this benefit was mostly limited to a minority of the population of older individuals.

Abstract Importance Estimating global lives and life-years saved is important to put into perspective the benefits of COVID-19 vaccination. Prior studies have focused mainly on the pre-Omicron period or only on specific regions, and lack crucial life-year calculations and often depend on strong modeling assumptions with unaccounted uncertainty. Objective To calculate the lives and life-years saved by COVID-19 vaccination worldwide from the onset of the vaccination campaigns and until October 1, 2024. Design, Setting, and Participants This comparative effectiveness study considered different strata of the worldwide population according to age, community-dwelling and long-term care residence status, pre-Omicron and Omicron periods, and vaccination before and after a SARS-CoV-2 infection. Exposures of doses. Any COVID-19 vaccination in any schedule and number Main Outcome Measure Death. Results In the main analysis, more than 2.5 million deaths were averted (1 death averted per 5400 vaccine doses administered). Eighty-two percent were among people vaccinated before any infection, 57% were during the Omicron period, and 90% pertained to people 60 years or older. Sensitivity analyses suggested 1.4 to 4.0 million lives were saved. Some sensitivity analyses showed a preponderance of the benefit during the pre-Omicron period.

An estimated 14.8 million life-years were saved (1 life-year saved per 900 vaccine doses administered). The sensitivity range was 7.4 to 23.6 million life-years. Most life-years saved (76%) were among people 60 years or older, but long-term care residents contributed only 2% of the total. Children and adolescents (0.01% of lives saved and 0.1% of life-years saved) and young adults aged 20 through 29 years (0.07% of lives saved and 0.3% of life-years saved) had very small contributions to the total benefit. Conclusions and Relevance Estimates in this study are substantially more conservative than previous calculations focusing mostly on the first year of vaccination, but they still clearly demonstrate a major overall benefit from COVID-19 vaccination during the years 2020-2024. Most benefits in lives and life-years saved was secured for a portion of older persons, a minority of the global population.

The research offers the first global estimate of both lives saved and life-years gained through COVID-19 vaccination between 2020 and 2024.

The study has been published in JAMA Health Forum. YES, it is PEER-REVIEWED
• jamanetwork.com/journals/jam...

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WELL NOW, would you look at that? A massive GLOBAL study revealed COVID-19 vaccines utilizing mRNA technology PREVENTED OVER 2.5 MILLION deaths WORLDWIDE between 2020 and 2024.

It reveals that vaccinations didn’t JUST protect against illness.

They PRESERVED nearly 15 MILLION years of human life.

Just a heads up. I was able to schedule my COVID vaccine appointment. Online it will ask “do you have a condition that puts you at high risk for severe outcomes from COVID-19 virus.”

Click yes and it will allow you to schedule an appointment.

No questions asked.

No proof required.

Pass it on.

there are many reasons to keep living despite The Horrors but one of the biggest ones is i have to find out what t4t flirting is like when we're all in our late fifties

What did the Lenacapavir studies show? Again, I previously wrote threads on these and you can find them here but I’ll give a quick summary as well.
• bsky.app/profile/sail...
• bsky.app/profile/sail...

likely to stay on the medication if they only need to take the medication twice a year, rather than daily oral doses which is a substantial advantage of Lenacapavir.

one month a part. The overwhelming majority of PrEP users take daily versions, but it can be hard to take a pill every day when it's for prevention. So it is possible to see adherence levels as low as 50% to 55%, which does not provide adequate protection for at-risk populations. People are more

So, how does Lenacapavir compare to other HIV prevention drugs? Pre-exposure prophylaxis, or PrEP, medications are sold as a daily pill under brand names Truvada and Descovy, as well as generic versions. Another injectable medication, Apretude, is taken every two months after two initial shots taken

Lenacapavir has shown to be remarkably effective (I previously wrote in-depth threads on their clinical trials) and it only needs to be given twice a year, which represents a whole new way of preventing HIV. Keep in mind, Lenacapavir has been studied and developed over nearly TWO DECADES.

An epidemic that's been sustained for 44 years might finally be quelled, with the milestone approval of the first HIV drug that offers 100% protection with its twice-yearly injections. It's a landmark achievement that stands to save millions of lives across the globe.

THIS IS HUGE! The FIRST 100% effective HIV PrEP drug, Lenacapavir, is APPROVED AND GOING GLOBAL. The makers are providing AFFORDABLE access to the drug in the United States AND beyond, signing ROYALTY-FREE licensing agreements with SIX generic manufacturers to produce AND supply it.
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dude this party is such an echo chamber. it's just friends hanging out and chilling and having a good time. you need to invite some people over who want to kill you with hammers

I am not an Elon Musk fan, but rhetoric about deporting him is really disturbing to me. He's a US citizen. Folks leaning towards authoritarianism want to strip people of their citizenships. We shouldn't want the same, even for the very worst of us. Either we have principles or we don't.

You can read all this and more here:
• www.nature.com/articles/s41...
• www.doherty.edu.au/our-work/ins...
• www.theguardian.com/global-devel...
• www.theguardian.com/global-devel...
• www.outinperth.com/australian-s...

the current study, which represents a major potential advance in delivery of mRNA for therapeutic purposes to blood cells. This discovery could have broader implications beyond HIV, with the relevant white blood cells also involved in other diseases including certain cancers.

•A 112-fold increase in multiply-spliced HIV RNA (Tat-Rev transcripts) •HIV transcription exceeded that triggered by standard mitogens (PMA/PHA) •A 17.2-fold increase in HIV virion production in culture medium. The new technique significantly outperformed earlier attempts using older nanoparticle designs, which failed to deliver mRNA to the right immune cells.

Fig. 5: CRISPRa-LNP X activates HIV transcription in CD4+ T cells from people living with HIV.

triggering unwanted cell activation. It is quite amazing that this is done without harming cells or setting off “immune alarms.”

After just one dose of Tat-LNP X, the study found: