CURE Epilepsy

Personalizing Electrical Stimulation for Focal Epilepsy The connectivity networks between the thalamus and cortex — termed thalamocortical hodology — may be used to treat focal epilepsy.

Highlights from epilepsy research this month:

🧬Fixing a Genetic Brain-Disorder Defect in Mice: https://bit.ly/4pkYA2j
🧠Personalizing Electrical Stimulation for Focal Epilepsy: https://bit.ly/3K07Qd5
🧪Creating CBD-Like Seizure Treatments Without Cannabis: https://bit.ly/4i6pXKM

Seizure Rescue Meds – CURE Epilepsy Learn about seizure recuse medications, including who they can help and what they do. Includes educational resources.

🚨 Take a look at the practical guide to #seizure rescue #medications, what they are, when to use them & what to ask your #neurologist. Dive in: https://bit.ly/4qWJAZO. Made possible by support from Neurelis. #rescuemedication #epilepsy #epilepsytreatment

New Study Brings Hope and Guidance for People Newly Diagnosed with Focal Epilepsy - Westchester Medical Center Health Network A WMCHealth-led study finds most people with newly diagnosed focal epilepsy can achieve seizure freedom, but it often takes over a year and multiple treatments. The research offers hope, clearer expec...

Research from the Human Epilepsy Project offers hope for people newly diagnosed with focal epilepsy, showing that seizure control takes time, teamwork, and personalized care. Early specialist support and precision medicine are key to better outcomes.

🔗 https://bit.ly/46sZsuV

Epilepsy Awareness Month Celebrate Epilepsy Awareness Month in November with CURE Epilepsy—help educate, advocate, and inspire action toward a world without epilepsy.

Happy Epilepsy Awareness Month! Join us celebrating the breakthroughs that help people live better—and reminding everyone why supporting research matters. 💜 #EpilepsyAwareness #CUREepilepsy https://bit.ly/436dtgg

When a genetic test in epilepsy returns a VUS, what’s next? 🧬 Dr. Gemma Carvill and the #ILAE team explain how clinical context + data sharing + the right tools can narrow the uncertainty. #Epilepsy #Genetics #VUS

Learn more: https://bit.ly/47uFyiI

Promotional image for the Partners Against Mortality in Epilepsy conference in Atlanta, featuring three attendees focused on a presentation, with event details and a 'Register Today!' call to action.

📅 Mark your calendars! Join leading voices in patient #advocacy, #epilepsy research, and #SUDEP prevention at the 2025 #PAME Conference December 4, 2025, in #Atlanta.

Registration is now open! https://bit.ly/3WQB4he

It's not too late to register for #AES2025! #epilepsy #neurology

📍 Atlanta | Dec 5–9
✅ Register now: buff.ly/LfiKcir

Submit Feedback | Epilepsy National Plan

📢 News on the National Plan for Epilepsy! The draft document outlining the goals is here for your feedback. Review the draft plan and provide feedback via online form by Friday, 11/31/2025: https://www.epilepsy-national-plan.org/submit-feedback/meeting/register/tZcrc-qgpzIpGNBbqqO0X0ocIzhzl99Sgv2H

Juvenile Myoclonic Epilepsy Explained Dr. Kelly Knupp, MD, answers your questions about Juvenile Myoclonic Epilepsy, or JME. Dr. Knupp, Pediatric Epileptologist at Children's Hospital of Colorado, explains what Juvenile Myoclonic Epilepsy is, how seizures present in JME, who is most often i...

📣 This month on Epilepsy Explained, Dr. Kelly Knupp explains Juvenile Myoclonic Epilepsy (JME), one of the most common epilepsy syndromes in teens and young adults. 📽️ Tune in now and learn more about JME: https://bit.ly/4hfY1Uw

Two members of the Maffie family stand in red CURE Epilepsy clothes with a sign that says, "Expect Nothing. Appreciate Everything." One woman is holding up the latest CURE Epilepsy impact report, which featured a photo of their family.

Runner wearing a "Cure Epilepsy" shirt participating in a marathon, waving at the camera among other participants on a sunny day.

Participant in a Cure Epilepsy shirt high-fiving spectators at a marathon event.

Participants and spectators at a marathon, with one runner with her arms out as if to say, "Ta Da!" Spectators holding supportive signs, on a sunny day.

Windy City, you blew us away! 👟🏅 Over 30 runners ran right past our goal, raising a fantastic $90,000 for epilepsy research! 💪 Thank you! And a big thanks to @sklifescience.bsky.social for powering Team CURE Epilepsy this year and to Method Printing for providing the shirts.

Fueled by Love, Driven by Purpose For nearly 30 years, Lisa and Randy Siegel have built a beautiful life for their children filled with love, success, and connection. Their daughter, Becca, is...

Becca Seigel lives with daily seizures, but her resilience shines through. ❤️ Her family’s love fuels hope and action. Now they’re helping CURE Epilepsy fund research for a cure.
📖 Read more: https://bit.ly/4nIXhtf

#EpilepsyAwareness #EpilepsyResearch #MedicalResearch

Four smiling individuals working at computers in a modern office, promoting the 'Unite to Cure Epilepsy' event on September 30, with a note about a 2X match active now.

Mark your calendar! On 9/30, meet Dr. Rachel June Smith and the budding scientists working in her lab for UNITE to CURE Epilepsy. Get the ball rolling by making a gift today: https://bit.ly/46nhYFf

Thank you so much for supporting Night of Discovery and making it an evening we'll never forget!

NIH Awards $8.6 Million Grant to Renew Rare Disease Clinical Research In a groundbreaking advancement for the field of neurodevelopmental genetics, Mustafa Sahin, MD, PhD, Neurologist-in-Chief and Chair of the Department of Neurology at Boston Children’s Hospital, a

🧬 The NIH awards $8.6M to renew the Rare Diseases Clinical Research Network for neurodevelopmental studies, led by OHSU. The project will study more than 15 different rare genetic brain disorders to improve diagnosis and care. #RareDisease #NIH #Neurogenetics

🔗 Read more: https://bit.ly/4nGMJur

This Epilepsy Explained answers questions about PTE, like:
🧠 Treatments and how effective they are
🧠 If a person suffers head trauma, are they at risk for the rest of their lives?
🧠 Are some meds better at treating depression in people with PTE?
Watch: https://bit.ly/3I0O6VS

Graphic featuring the United States Capitol with text 'Advocating for Epilepsy Research - NIH Funding Update'.

📢 Cautious optimism for #NIH: A House subcommittee advanced a FY26 bill with $46.9B for NIH, slightly above current levels and far better than the 40% cut proposed earlier. The full #House and #Senate must still agree, and a CR may be needed to avoid a shutdown on Sept. 30. #epilepsyresearch

Early-Onset Neonatal Infection and Epilepsy in Children Exploration of the association between early-onset neonatal infection, specifically sepsis and meningitis, and childhood epilepsy.

Infections at birth like neonatal sepsis or meningitis may up the odds of childhood epilepsy. Stronger effects seen in focal vs generalized epilepsy. Early prevention & treatment of newborn infections could help reduce this risk. 🔍

🔗 More details: https://bit.ly/3Vi5RTu

Collage promoting "Researching for a Cure 2024-2025". Top left: Person sitting for an interview outdoors. Top right: Person conducting a laboratory experiment. Middle left: Person analyzing samples under a microscope. Middle right: Large text "RESEARCHING FOR A CURE 2024-2025" with stars. Bottom left: Neural network graphic. Bottom right: Person running in a marathon with spectators watching. Text includes statistics such as "$5.2M in program investments" and "30 grants under management".

You made a big impact!
💜 $5.2M+ in research
🔬 30 active grants
📚 2 staff publications
🏃 28 Champion events nationwide

Together, we're driving change in epilepsy research. THANK YOU for standing with us! 🙌 More: https://www.cureepilepsy.org/our-research/impact-reports/researching-for-a-cure-2025/

UCLA researchers used stem cell‑derived assembloids to show how SCN8A variants trigger cortical hyperactivity (seizures) and impair hippocampal rhythms (memory). This new model may explain cognitive challenges beyond seizures and open avenues for better treatments.

Read more: https://bit.ly/41O86BE

Long-term Hippocampal Low-Frequency Stimulation Alleviates Focal Seizures, Memory Deficits and Synaptic Pathology in Epileptic Mice Insights into the seizure type-specific effects of hippocampal low-frequency stimulation, and support for the idea that it could contribute to enhanced seizure control and quality of life in Mesial te...

🔬 Epilepsy Research News:
Hippocampal low-frequency stimulation (LFS) in a mouse model of drug-resistant focal epilepsy (MTLE) led to:

🔻 Reduced seizures
🧬 Reversed memory deficits
🧠 Better synaptic health

🔗 Read more: https://bit.ly/4pekViu

Two attendees standing behind a lectern at the 36th International Epilepsy Congress in Lisbon, Portugal, featuring the ILAE logo and IBE logo.

This weekend at #IEC2025, our CSO Dr. Laura Lubbers joined Dr. Dan Lowenstein for the Presidential Symposium on inclusive, patient-centered epilepsy care. She also shared updates on SUDEP Common Data Elements led by CURE Epilepsy. #ILAE #SUDEP #epilepsyresearch

Insulin Resistance in the Brain may Link Alzheimer’s and Epilepsy New research has shown that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.

Brain #insulin resistance may link #Alzheimer’s and #epilepsy — new research supports the "type 3 diabetes" hypothesis and its role in both memory loss and #seizures. A promising step toward better understanding and #treatment. 🧠✨

Learn more: https://bit.ly/44I1ypW

AANN and PAME Webinar: Seeing the Whole Patient: Suicide, Screening, and Mental Health in Epilepsy Join us live on September 26th at 12pm CT (10am PT/11am MT/1pm ET) for this webinar, presented by AANN and PAME (Partners Against Mortality in Epilepsy). This webinarwill discuss the personal and emot...

Join PAME and Association of Neuroscience Nurses Sept 26 @ 1PM ET for a powerful webinar on suicide prevention, screening, and #mentalhealth in #epilepsy.

Hear from expert clinicians + a mother’s story of loss and advocacy through Widdy’s Work.

📅 Register: https://bit.ly/4mLG16t

High Blood Pressure in Pregnancy Linked to Increased Risk of Seizure in Children A new study has revealed a significant association between high blood pressure during pregnancy (gestational hypertension) and an increased risk of seizures in children.

New research links high blood pressure during #pregnancy to an increased risk of #seizures in children. Maternal health may play a critical role in long-term #neurological outcomes.

🔗 Read more: https://bit.ly/4kF0yHT

#EpilepsyResearch #MaternalHealth #SeizurePrevention

High Blood Pressure in Pregnancy Linked to Increased Risk of Seizure in Children A new study has revealed a significant association between high blood pressure during pregnancy (gestational hypertension) and an increased risk of seizures in children.

New research links high blood pressure during #pregnancy to an increased risk of #seizures in children. Maternal health may play a critical role in long-term #neurological outcomes.

🔗 Read more: https://bit.ly/4kF0yHT

#EpilepsyResearch #MaternalHealth #SeizurePrevention

September is Newborn Screening Awareness Month, and we have a full calendar of opportunities for you to learn and engage!

👉 To register and find more details visit our events calendar here: everylifefoundation.org/events-sched...

#newbornscreening #awarenessmonth #nbs #policy #raredisease

MEG Explained Rescue Medications Explained Dr. M Scott Perry, Head of Neurosciences at the Jane and John Justin Institute for Mind Health at Cook Children’s Hospital, answers your questions about MEG, or magnetoencephalography.

In this Epilepsy Explained video, Dr. Perry breaks down what #MEG is, how it works, and why it matters for people living with #epilepsy. He answers some of the most frequently asked questions about its #clinical use and potential benefits.

🔗 Learn more: https://bit.ly/3GvMWRr

Promotional graphic titled 'Stand Together Against Prolonged Seizures' featuring a silhouette of people with raised arms against a starry night sky.

Do you or a loved one experience epileptic seizures lasting over than 3 minutes? The STARS Study is a global clinical study testing an investigational inhaler that may help stop a prolonged seizure after it starts.

Learn more about the STARS Study from UCB here: https://www.starsepilepsystudy.com/

Event banner for Night of Discovery by CURE Epilepsy, featuring names of Platinum sponsors including Cafaro-Livingston Charitable Trust and Grosvenor GCM, and Diamond sponsors Lisa & Mike Cotton and The Ann G. & James B. Ritchey Foundation.

Thank you so much to our Night of Discovery Platinum and Diamond Sponsors! We are so grateful for their generosity and commitment to finding cures for epilepsy. There's still time to join us as a sponsor of this year's Night of Discovery! Learn more here: https://Discovery2025.givesmart.com

The BIPARTISAN National Plan for Epilepsy is incredibly important. Please learn about it and support it, including contacting your representatives and senators.