the computational brain lab

Graphical summary of the paper entitled : "Macaque prefrontal cortex integrates multiple components for metacognitive judgments of working memory"

Using calcium imaging in macaque PFC during a meta–WM task, we show that PFC jointly encodes remembered locations + uncertainty.

PFC integrates WM strength + cues into a meta-WM signal that guides behavior.

A collab btw our team and Liping Wang group

doi.org/10.1016/j.ne...

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A non-monotonic code for event probabilityin the human brain. Nature Communication, Foucault et al, 2025

Using 7T fMRI, our team found a representation of the probability of the next event in human dlPFC —and it’s highly non-monotonic.
Confidence signals, in contrast, were mostly monotonic.

doi.org/10.1038/s414...

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Thank you Nicole!

Nicole's wonderful book 'Elusive Cures' has played an important role in pushing me out of my comfort zone and join forces w/ @philippedomenech.bsky.social and @bellecguill.bsky.social, here.

Exciting times ahead for neuroscience.

Go read it, if you haven't yet!

Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻

Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems.

See below for + details and retweet 🙏

🚨 !!! New preprint !!! 🚨
MULTIMODHAL (phase 3, multicenter double-blind RCT): fMRI “symptom-capture”–guided neuronavigation significantly improves 1-Hz rTMS outcomes for drug-resistant auditory verbal hallucinations vs standard T3P3 targeting. 🧠🟦

#rTMS #Psychiatry #Schizophrenia #fMRI

Researchers in France are working on creating a french network of researchers to organize interaction, communication and training in #Computational_Neuroscience. If you are a CompNeuro working in France, consider joining, and registering to our mailing list: listes.services.cnrs.fr/wws/subscrib...

Is Tan et al. The End of Social Science Genomics? What happens when everything is unconfounded?

"Polygenic scores for complex human behavior don’t work"

ericturkheimer.substack.com/p/is-tan-et-...

Recasting adaptation as strategy inference Flexible adaptation to uncertain and changing environments requires dynamic adjustments in behavioral strategies. While classical learning theories emphasize incremental strengthening of local stimulu...

Excited to share our preprint: "Recasting adaptation as strategy inference". This work explores how humans spontaneously adapt to changes by inferring strategies, rather than relying on incremental learning.@philippedomenech.bsky.social @khamascience.bsky.social @computationalbrain.bsky.social 🧠🟦 🧠🤖

This guy is speaking at 'legendary Piano Vache bar 🍺' this Friday at 5pm (one free drink included!)

75% of US scientists who answered Nature poll consider leaving More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

The massive changes in US research brought about by the new administration of President Donald Trump are causing many scientists in the country to rethink their lives and careers

https://go.nature.com/41OhAgK

The unparalleled XJ Wang has written a book about the computations underlying cognition. I read a draft version and it is awesome. He is not on social media, so I am sharing it on his behalf :)

Recasting adaptation as strategy inference https://www.biorxiv.org/content/10.1101/2025.03.24.645064v1

Too much or not enough? Optimal level of human intracranial theta activity for rule-switching in the subthalamo-medio-prefrontal circuit. 🧠🟦 🧠🤖

www.biorxiv.org/content/10.1...

Are you a (computational) neuroscientist looking for a postdoc?

Come to Paris!

There are plenty of great labs always looking for talent, including our own