Jeff Leek

Jeff Leek Help Fred Hutch Cancer Center advance innovative research. Donate today!

My family and I are going to be running the 5k at Obliteride again this year! (we'll be biking as soon as the boys are old enough :)). We are raising funds for data science and AI efforts to find cancer cures at the Fred Hutch, consider donating if you are able! secure.fredhutch.org/site/TR/Obli...

Wild congratulations to one of the most incredible people I’ve ever worked with. @benlangmead.bsky.social I hope you are celebrating this very well deserved honor!!!

An estimate of the science-wise false discovery rate and application to the top medical literature - PubMed The accuracy of published medical research is critical for scientists, physicians and patients who rely on these results. However, the fundamental belief in the medical literature was called into seri...

Also empirical estimates don't agree with the simulation....

pubmed.ncbi.nlm.nih.gov/24068246/

These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.

Damn... I wonder why scientists wouldn't want to come to the US to compete at the highest levels for highly-restricted funding that then gets pulled surreptitiously for some imagined reason or no reason at all, all while being vilified by the federal government for their work? A mystery! 🤔

Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.

If you are around Seattle, see ya there :)

Bright and early talk by @jtleek.bsky.social at the Princess Margaret Cancer Centre Grand Rounds on building and scaling AI engines in oncology.

NOOOOOOOOOOOOOOOOOOOOOO

Congratulations to the @jxtxfoundation.bsky.social scholarship winners for the 2025 Biology of Genomes conference @cshlnews.bsky.social! Learn more about their research and the scholarship program here: jxtxfoundation.org/news/2025-3-... #bog25

Synthesize Bio's platform is awesome as a teaching tool. In just a couple of minutes you can (a) find a dataset, (b) run a validated workflow like @mikelove.bsky.social's published EDA workflow, and (c) share with your friends:
app.synthesize.bio/notebooks/3a...

This alliance helps solve the key technical challenges that will enable us to securely use both #AI and massive computational power to find these breakthrough insights and save more lives. Congrats to the CAIA team on this well-deserved recognition! #oncsky

An incredible honor and the momentum is building for the Cancer AI Alliance. We have been hard at work behind the scenes - expect more public from us soon! @brianmbot.bsky.social (pictured) and the broader CAIA team are amazing and it is fantastic to see their work rewarded.

Amid federal funding uncertainty, cancer center leaders forge ahead - Becker's Hospital Review | Healthcare News & Analysis Facing federal funding uncertainty, a looming workforce shortage and an increasingly aging patient population, cancer center leaders in the U.S. remain undeterred. Their focus remains, as it has for d...

We are in a period of remarkable progress in cancer research and care. It’s critical that we don’t let near-term pressures immobilize us and lose sight of our long-term plans. Thanks to Becker’s Hospital Review for inviting me to share what's at stake. www.beckershospitalreview.com/oncology/ami...

Really excited about releasing our platform for integrating gene expression data - search for and easily integrate multiple datasets app.synthesize.bio/datasets, analyze them in Notebooks, and sign up for our beta for AI-generated gene expression data from experimental designs!

Check this out - the company I co-founded is trying to figure out how to make this super easy product.synthesize.bio (and we have beta models out to AI generate new expression data based on experimental design!)

The beta version of Synthesize Bio is up! You can jump right to playing with data!

- Pull ready-to-go publicly available gene expression data.

- Play around with this data using notebooks.

- Request access to the beta version of AI data generation.

product.synthesize.bio!

NIH guts its first and largest study centered on women The Women’s Health Initiative has produced numerous influential findings

This is beyond short sighted. www.science.org/content/arti...

The Women’s Health Initiative is simultaneously a gold standard for how to do large scale research, a huge impact study, a long term investment, and one of the best resources for AI in science.

I’m just gutted for everyone involved

Cancer mortality rates have been dropping because of NIH and NCI funded research to Universities. Without it there would be no new cancer treatments that save lives.

We are looking for someone who knows how to just get things done—navigating complex systems with speed, precision, innovation, and diplomacy.

Fred Hutchinson Cancer Center Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.

The Cancer AI Alliance (www.canceralliance.ai) is hiring for a full time Director of Operations role careers-fhcrc.icims.com/jobs/29460/c... This role will drive execution across legal, financial, research compliance, philanthropy, and business development.

Opinion | The Uncertain Fate of the Young American Scientist (Gift Article) Young researchers are choosing between staying in science and staying in the United States.

www.nytimes.com/2025/04/03/o...

Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security

Google Cloud and Ai2 Commit $20M to Advance AI-Powered Research for the Cancer AI Alliance /PRNewswire/ -- Today, Google Cloud and Ai2 announced they have partnered with the Cancer AI Alliance (CAIA), a pioneering consortium uniting leading cancer...

Excited to officially welcome Google and AI2 to the Cancer AI Alliance !

www.prnewswire.com/news-release...

The alliance is enabling us to move at incredible speed and still being super careful about data thanks to the big collaborative team of experts!

Check out this awesome new R package for simplifying working with AWS from folks at @fredhutch.bsky.social recology.info/2025/04/sixt...

Public health biostatistics has always been incredibly important; but in this moment even more so! Consider nominating an early career biostatistician for our field's most prestigious award: www.spiegelmanaward.org by May 1! This is an opportunity to highlight how biostatistics helps so many people

👏 Huge congratulations to Assistant Prof @lucystats.bsky.social for her Emerging Leader Award from the Committee of Presidents of Statistical Societies!

2025 GeekWire Awards

Our Cancer AI Alliance is up for Health Innovation of the Year for the Seattle-based Geekwire awards!

www.geekwire.com/events/2025-...

@fredhutch.bsky.social is very proud to represent our Alliance - we'd love your vote for the hard work being done by all of the people involved!

Dr. Anderson reflecting that what drove the original recruitment was altruism and the legacy participants would leave for their daughters and grand daughters by participating

Watching one of the world’s leading scientists talk about one of the world’s most important studies; Garnet Anderson from @fredhutch.bsky.social reflecting on 30 years of the Women’s Health Initiative. Such an incredible force for good over 3+ decades

This is an incredibly important post by @rafalab.bsky.social on our Simply Statistics blog (its still around!) on why "indirect costs" are spent on research and its not enough! simplystatistics.org/posts/2025-0...