Horst Obenhaus

I am glad you are voicing these concerns and I totally agree with you.

It's not in the docs, but yes, you could do that if you can calibrate your FOVs. We don't offer 3D calibration procedures atm, but that's something we hint at in the discussion of our preprint. So if you are interested in that this would definitely be something we could solve! @claynerd.bsky.social

You can use #OCTRON to track cells too!

It took 10 min to annotate multiple cells in 146 frames, 1.5 hrs to train a model with a GPU, and 10 sec to make these predictions. It doesn't get much easier than that⚡️

We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:

Where does learning through imitation happen in the brain?

In juvenile zebra finches, we pinpoint a synaptic locus of song learning in a cortico-basal ganglia circuit and leverage this localization to measure the timescale of consolidation and make birds learn faster! #neuroskyence (1/14)

This felt good.

YouTube video by Cell Press Flexible use of a multi-purpose tool by a cow / Curr. Biol., Jan. 19, 2026 (Vol. 36, Issue 2)

This must be one of the most wholesome videos I have ever seen, accompanying a publication 🐄🐂https://www.youtube.com/watch?v=SGVo41MuLiQ

Ze Frank IS the best!

What a beauty!

Such fun and a real privilege to write this Journal Club article in @natrevneuro.nature.com. Introducing a fascinating creature and what it teaches us about behavioural coordination rdcu.be/eZnKn

Predictive coding of reward in the hippocampus - Nature Calcium imaging of mouse hippocampal neurons while mice learn a reward-based task over several weeks provides insight into the evolution of the hippocampal reward representation during extended periods of experience.

Nature research paper: Predictive coding of reward in the hippocampus

go.nature.com/49mB13V

They look friendly!

That’s cool - looking forward to reading the next chapter (: !

Interesting stuff. I wonder how this will work when the background is noisy and moving (like in vivo). It seems to me like you will loose some of the advantage that you gain here when recording with blank background (like in your cultures). Any ideas on how to deal with noise-limited scenaria?

Epic! Straight from the fantasy movie!

Ultra-wide-field, deep, adaptive two-photon microscopy Observing the activity patterns of large neural populations throughout the brain is essential for understanding brain function. However, capturing neural interactions across widely distributed brain r...

A new version of our 2p mesoscope paper is up on biorxiv:
Yang et al, Ultra-wide-field, deep, adaptive two-photon microscopy.
www.biorxiv.org/content/10.1...

recently my friend's comics professor told her that it's acceptable to use gen AI for script-writing but not for art, since a machine can't generate meaningful artistic work. meanwhile, my sister's screenwriting professor said that they can use gen AI for concept art and visualization, but that it won't be able to generate a script that's any good. and at my job, it seems like each department says that AI can be useful in every field except the one that they know best. It's only ever the jobs we're unfamiliar with that we assume can be replaced with automation. The more attuned we are with certain processes, crafts, and occupations, the more we realize that gen AI will never be able to provide a suitable replacement. The case for its existence relies on our ignorance of the work and skill required to do everything we don't.

it’s come to my attention that my tumblr post has been crossposted to bluesky, so I’m posting it on my account here #AntiAI #GenAI

Plastic landmark anchoring in zebrafish compass neurons - Nature Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.

Nature research paper: Plastic landmark anchoring in zebrafish compass neurons

go.nature.com/4qP4HwB

Wow this looks big. Imagine what we could design!

Interesting advice on running a research team Max Planck Style.

If you run out of space, the architects will expand the building.

If people disagree with you in articles, fly them in talk to them.

Quite a different world to most of academia!

onlinelibrary.wiley.com/doi/10.1002/...

Track everything you want - with OCTRON 💙

So … definitely “ouch” ! (:

This is not about whether cognitive maps exist or not. The article simply summarizes that one of the most cited articles (!) is not replicable and what might be the reason for it. It’s important to know for everyone referencing Tolman’s work. Behavioural analysis is complex!

Beautiful model! 😍 Is it available somewhere?

If anyone is or knows a PhD with EEG experience who is a) eligible for a Marie Curie post doc and b) interested in an ecological neuroscience project based in Leeds, let me know. I have an idea that needs a person!

Tolman's Sunburst Maze 80 Years on: A Meta‐Analysis Reveals Poor Replicability and Little Evidence for Shortcutting In 1946, Tolman et al. reported that rats could take a novel shortcut to a goal after training on an indirect route, supporting the Cognitive Map theory. However, a review of subsequent Sunburst maze...

Can humans & animals really use internal maps to take shortcuts?

Tolman famously said yes - based largely on his Sunburst maze.

Our new review & meta-analysis suggests evidence is far weaker than you might think.
🧵👇 doi.org/10.1111/ejn....

@uofgpsychneuro.bsky.social @ejneuroscience.bsky.social

😂… #NationalBirdDay

Ultrashort optical-pin excitation for scattering brain imaging https://www.biorxiv.org/content/10.64898/2026.01.04.697592v1

Screenshot of the tessellated materials website

Beautiful collection of all kinds of tessellated materials in nature tessellated-materials.mpikg.mpg.de?tile_shapes_... #HUBerlin

What is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...