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Nick Constantino

@ncons95.bsky.social

Neuroscience PhD candidate at the University of Kentucky | Boston University ‘18 | Sleep, metabolism and Alzheimer’s disease | Views are my own | https://www.macauleylab.com

165 Followers  |  387 Following  |  2 Posts  |  Joined: 22.11.2024  |  1.4941

Latest posts by ncons95.bsky.social on Bluesky

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Tau pathology reprograms glucose metabolism to support glutamatergic activity and excitatory imbalance Alzheimer's disease (AD) is not only characterized by amyloid-beta (Aβ) and tau pathology, but also by early and progressive disruptions in metabolism. Neuronal excitability is tightly coupled with me...

🔥New preprint from the lab! Led by @rileyirmen.bsky.social

Tau pathology reprograms glucose metabolism to support glutamatergic activity and excitatory imbalance

📍 biorxiv.org/content/10.1101/2025.07.25.666872v1

🧵 on how tau disrupts the metabolism–excitability balance in Alzheimer’s disease

31.07.2025 15:48 — 👍 7    🔁 5    💬 2    📌 0
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Fueling sleep: UK researchers show key metabolic link to restful nights Scientists have long recognized the brain’s need for energy, but groundbreaking research from the University of Kentucky’s Sanders-Brown Center on Aging has now illuminated how the brain’s energy uti...

A great write up on our recent work in PNAS attempting to understand metabolic drivers of sleep, led by @ncons95.bsky.social !

uknow.uky.edu/research/fue...

27.03.2025 14:02 — 👍 31    🔁 12    💬 0    📌 0
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Macauley Lab needed a win today!

Thank you to UK Women’s Basketball for providing it. What a great first round win!!!

And there was ice cream. Yum!

@ncons95.bsky.social @rileyirmen.bsky.social

21.03.2025 21:17 — 👍 14    🔁 2    💬 0    📌 0

Thank you! @jmcastell.bsky.social

18.02.2025 23:33 — 👍 0    🔁 0    💬 0    📌 0

Super excited to have my first 1st author paper out today! Thanks to all of our collaborators and my mentor @macauleylab.bsky.social !

18.02.2025 21:56 — 👍 3    🔁 0    💬 1    📌 0
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Freeze on NIH Grant Reviews Leaves Scientists Confused and Frustrated An unprecedented federal ban on scientific meetings halts research progress, sparking widespread concern across the scientific community.

Grateful to The Scientist for listening to my story and amplifying our concerns regarding bans on NIH communication and govt funding. www.the-scientist.com/freeze-on-ni...

29.01.2025 13:43 — 👍 39    🔁 11    💬 3    📌 0

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