Patrick MacDonaldπŸ‡¨πŸ‡¦'s Avatar

Patrick MacDonaldπŸ‡¨πŸ‡¦

@bcellorg.bsky.social

Professor. CRC. University of Alberta. University of Michigan. Diabetes. Biobanking. Cells, tissues, data. HumanIslets.com, IsletCore.ca, bcell.org

920 Followers  |  1,291 Following  |  92 Posts  |  Joined: 11.10.2023  |  1.6625

Latest posts by bcellorg.bsky.social on Bluesky

This! Fancy web interfaces let you explore the data, but they are not the same as sharing the data. You can do both!

31.10.2025 19:16 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Open Letter to Protect Tri-Council EDI Data Why do we need urgent action to protect our data? The mandate of the House of Commons Standing Committee on Science and Research is to review and report on topics relating to science and research in ...

If you are a Canadian scientist interested in the protection of identifying information about applicants and reviewers of tricouncil grants please read and sign this letter. Thank you. docs.google.com/forms/d/e/1F...

31.10.2025 18:31 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1

πŸ“’ Support Our Science in the news!

We’re proud to be featured in CTV News’ latest story on Canada’s emerging β€œbrain gain” β€” a scientific migration as researchers look north amid challenges in the U.S.

22.10.2025 00:31 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0

Doesn’t EGA have a node in Sweden specifically for controlled access sharing of this type of data?

https://fega.nbis.se

17.10.2025 13:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Interesting paper, but does anyone know if the claim that β€œβ€¦The datasets (genome-wide raw sequencing and individual-level clinical data) … are not publicly available due to EU and national legislation” is reasonable?

https://www.nature.com/articles/s41598-025-21595-1

17.10.2025 13:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

🧡(1/4) For the first half of October 2025 we have 3 publications from the CIRTN labs🍁. These papers are from the groups of Drs. Bruce Verchere, Yi-Chun Chen, Francis Lynn, James Shapiro, Tatsuya Kin and Guy Rutter!

16.10.2025 01:57 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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@lukaszukab.bsky.social on Bluesky #ForeverCanadian crew is set up by the pumpkin weighing station (near the museum) at the Smokey Lake pumpkin festival. πŸŽƒ Come on over and sign the petition, please! πŸ‡¨πŸ‡¦
04.10.2025 15:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Today, #ForeverCanadian brought 230,000 petition signatures to Edmonton. Our volunteers will continue collecting signatures until October 28. We need your signature to reach our 300,000 requirement to keep Alberta in Canada.

#ableg #Yeg #Yyc #CdnPoli

03.10.2025 20:36 β€” πŸ‘ 304    πŸ” 148    πŸ’¬ 13    πŸ“Œ 25

🧡(1/7)We are now out of September🍁! From the last two weeks we have had publications from the CIRTN labs of Drs Jenny Bruin, Mourad Ferdaoussi, Peter Light, Patrick MacDonald, James Shapiro and Bruce Verchere!

01.10.2025 20:50 β€” πŸ‘ 14    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0
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Novel insights into the molecular underpinnings of islet cell dysfunction in #T1D highlighting pathways that may be leveraged to preserve residual Ξ²-cell function and modulate Ξ±-cell activity @bcellorg.bsky.social www.jci.org/articles/vie...

30.09.2025 16:45 β€” πŸ‘ 32    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0

And a special thank you to the organ donors, and organ procurement organizations and coordinators across the country (BC Transplant, Alberta Health Services / Give Life Alberta, Ontario Health / TGLN, Quebec Transplant, MOTP Atlantic Canada).

30.09.2025 13:08 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Over the past, nearly 15 years, our team has isolated more than 140 million pancreatic islets in support of diabetes and transplantation research across three continents.

30.09.2025 13:08 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Cake

Cake

Celebrating 600

Celebrating 600

Islets for research

Islets for research

Yesterday we celebrated our 600th human research islet isolation in support of diabetes research (and then last night isolated the islets in the pic). I’m very fortunate to work with such a dedicated team! See more at www.isletcore.ca

30.09.2025 13:08 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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Join us for the revival of the Islet Biology and Diabetes Keystone symposia in Breckenridge, Colorado on March 16-19, 2026, for great science and great skiing. You can register now for early bird rates: lnkd.in/dw59T7tc Joint with Gut-Brain Axis. @linnemannlab.bsky.social Erica Nishimura, Barak Blum

24.09.2025 21:38 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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Opinion: Yes, Canadians - Albertans do want to stay in Canada Don’t believe the separatist rhetoric of a few vocal and misguided pundits

My column in the Globe & Mail:

β€œThose challenges notwithstanding, separation is clearly not the answer. Even the talk of separation damages Alberta’s reputation, creates uncertainty, drives away talent and investment, and divides communities.”

#cdnpoli

www.theglobeandmail.com/opinion/arti...

29.09.2025 11:49 β€” πŸ‘ 294    πŸ” 108    πŸ’¬ 8    πŸ“Œ 6

Decision to cancel my season tix….justified again.

27.09.2025 16:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Coalition for Canadian Research calls on federal government to fulfil the Budget 2024 research commitments The Right Honourable Mark Carney, P.C., M.P.Prime Minister of CanadaOffice of the Prime Minister80 Wellington StreetOttawa, ON K1A 0A2

Research is the key to unlocking Canada’s future and it needs proper funding.

The federal government must uphold its Budget 2024 commitment to Canadian researchers.

Read the Coalition for Canadian Research’s open letter: www.caut.ca/news/coaliti...

25.09.2025 14:30 β€” πŸ‘ 13    πŸ” 20    πŸ’¬ 0    πŸ“Œ 1

Join us this Friday am, in person or online, for new insights into #Islet biology-what should we strive for in islet cell replacement therapy?-some thoughts from Professor Powers, a leader in the field in characterizing human islets across the lifespan #diabetes

24.09.2025 18:19 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Hello! Welcome to the CIRTN-R2FIC BlueSky account! Our group focuses on researching pancreatic islet biology and pathology related to islets such as type 1 and type 2 diabetes.
Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.

12.09.2025 21:12 β€” πŸ‘ 15    πŸ” 16    πŸ’¬ 1    πŸ“Œ 0

So I found out on the phone. Not sure that's clear online - at least it wasnt' to me....

12.08.2025 16:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Just phoned, trying to book as an immune compromised individual. No luck. β€˜Pre-book and then check in October’ was the response.

12.08.2025 13:47 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Heparan sulfate fine-tuned interleukin-1 (IL-1) signaling inhibits insulin secretion of grafted pancreatic islets The binding of heparan sulfate to IL-1Ξ± potentiates the inhibitory action of IL-1Ξ± on insulin release.

From the Ampofo group!

www.science.org/doi/10.1126/...

09.08.2025 14:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Spatially Bound Functional Heterogeneity Drives Modular Organization in Beta Cell Networks - PubMed Coordinated responses of pancreatic beta cell networks to changes in extracellular nutrient concentrations are a well-established phenomenon with significant implications for insulin secretion. This s...

Spatially Bound Functional Heterogeneity Drives Modular Organization in Beta Cell Networks

Maja Duh Marko Ε terk, Lidija KriΕΎančiΔ‡ Bombek, Patrick E MacDonald, AndraΕΎ StoΕΎer, Marko Gosak

pubmed.ncbi.nlm.nih.gov/40765144/

07.08.2025 12:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is now a long-distance relationship, Tim.

#cdnpoli

01.08.2025 22:07 β€” πŸ‘ 21    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0

The official post:

apps.ualberta.ca/careers/post...

25.07.2025 22:44 β€” πŸ‘ 5    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

1/ Canadian govts appear to have decided that they can not or will not fund higher education properly. But they won't admit this, preferring to tell institutions to enshittify themselves and shut up.

There are two options: one is slow starvation, the other is radical deregulation.

27.07.2025 13:26 β€” πŸ‘ 56    πŸ” 24    πŸ’¬ 5    πŸ“Œ 0

Guys y’all have the first overtly pro-cancer HHS leaders. Literal death cult. If I was an American, I’d be in the streets every day protesting

25.07.2025 22:21 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

The official post:

apps.ualberta.ca/careers/post...

25.07.2025 22:44 β€” πŸ‘ 5    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
Edmonton

Edmonton

Official posting coming soon, but here's a heads-up:

#Postdoc Opportunity for individuals with an interest in advancing the understanding of pancreatic islet hormones in health and #diabetes. Diverse backgrounds, skill sets and experiences are welcome!

www.bcell.org

24.07.2025 22:00 β€” πŸ‘ 14    πŸ” 16    πŸ’¬ 1    πŸ“Œ 2
Alberta Diabetes Institute

Alberta Diabetes Institute

Patch-clamp rigs

Patch-clamp rigs

Pancreas during islet isolation

Pancreas during islet isolation

24.07.2025 22:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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