Gut Microbiota for Health

Some #microbes may sound spooky, but behind their names lies a fascinating ecosystem that regulates digestion, immunity, and metabolism.

Discover our #SpookyButGutFriendly campaign and help make our microbes go viral (in the good way)!
https://loom.ly/_pN2lQY

Nutrition and microbiome research highlights from NeuroGASTRO 2025 The 6th biennial meeting of the European Society of Neurogastroenterology and Motility, held at Queen Mary University of London, UK, from 4-6 September 2025, covered basic, translational, and clinical research in neurogastroenterology, including dietary therapies and ‘biotics’ for the management of gastrointestinal disorders. Find out more about the main takeaways from the conference.

🧬 From diet to next-generation ‘biotics’, the latest #NeuroGASTRO2025 meeting in London showcased cutting-edge research in gut–brain and microbiome science.

Read the key highlights from the conference 👇
https://loom.ly/W9K9XKo

👻 Something “spooky” is coming to Gut Microbiota for Health...
#SpookyButGutFriendly

Another reason to promote breastfeeding: It protects babies against antibiotic resistance The gut microbiome plays a crucial role in children’s health, but factors such as cesarean birth and early antibiotic exposure can disrupt it. A new study shows that exclusive breastfeeding for at least the first month of life can help restore microbial balance and limit antibiotic resistance genes.

Breastfeeding and antibiotic resistance: what science reveals
A new study shows how exclusive breastfeeding in the first month of life supports a balanced infant microbiome and helps limit antibiotic resistance genes.
https://loom.ly/n6QVuKE

The gut Microbiome may affect immunomodulation and cancer therapy outcomes

Here's what scientists know and don't know and major implications for clinical practice @amergastroassn.bsky.social
https://www.gastrojournal.org/article/S0016-5085(25)00755-3/fulltext

Feed your microbes to improve gut and mental health Growing evidence from the microbiome field shows that harnessing gut microbes through diet can beneficially impact brain and behaviour. Which gut microbiome-targeted interventions have been studied as potential approaches for mental health?

🧠 Psychobiotics are interventions that act through the gut microbiota to support mental health.
From probiotics to fiber-rich and fermented foods, research is uncovering new links between the gut and brain.
#WorldMentalHealthDay
🔗 https://loom.ly/SOZKYFQ

Effect of Dietary Fiber Intake on Chronic Low-Grade Inflammation in Children and Adolescents: A Systematic Review and Meta-analysis of Randomized Controlled Trials Previous research suggests that dietary fiber (DF) intake may help reduce chronic low-grade inflammation (CLGI), a condition linked to the early development of cardiometabolic risk factors. Childhood ...

Fiber intake may help reduce chronic low-grade inflammation in children

Another piece of evidence that interventions targeting the gut microbiome early in life help prevent cardiovascular diseases
cdn.nutrition.org/article/S247...

Have you seen the new #AEProbio guide to probiotics available in the United Kingdom 🇬🇧?
This Guide has been developed to assist with decision-making regarding science-backed probiotic products: t.co/mj5RMvA6h8

Clinical translation of microbiome research: takeaways from the 2025 GMFH Summit The 13th Gut Microbiota for Health World Summit took place 15-16 March 2025 in Washington, D.C., and it focused on advances in microbiome research to diagnose, prevent, and manage gastrointestinal and extra-intestinal conditions. Find out more about the most valuable takeaways from the event.

Couldn't make it to #GMFH2025?
Here we bring you what's new and interesting on microbiome-based therapeutics from bench to bedside:

https://www.gutmicrobiotaforhealth.com/clinical-translation-of-microbiome-research-takeaways-from-the-2025-gmfh-summit/

Patients’ expectations and beliefs in IBS: Why gluten and wheat might not be the culprit Many patients with IBS find that wheat or gluten triggers gastrointestinal symptoms, prompting them to exclude these foods from their diets. A new study highlights how patients’ expectations and beliefs shape symptom modulation and dietary choices in IBS.

🥖 Many with IBS avoid gluten or wheat—but is it always necessary?

A new trial led by Dr. Premysl Bercik suggests that beliefs and expectations may drive symptoms more than the ingredients themselves.
https://loom.ly/KZQ0PxM

What are the many “known unknowns” on the microbiome, exposome, & cognitive development?
@maburto.bsky.social @jatinnagpal.bsky.social @jfcryan.bsky.social https://loom.ly/oUMFc0w

Microbiome highlights from Digestive Disease Week 2025 Digestive Disease Week 2025 featured recent basic, translational, and clinical research into the microbiome. Find out more about the main takeaways relevant for your clinical practice selected by GMFH editors.

🔬 What’s new in microbiome science from #DDW2025?
From the small intestinal microbiome to next-gen therapies, SIBO, fiber, and off-label use of live biotherapeutics—here are 5 key takeaways selected by the GMFH editorial team 👇
https://loom.ly/HMmEusw

Gut microbiota and atherosclerosis Atherosclerosis reflects a chronic inflammatory process of arteries. The origin of chronic vascular inflammation has been associated over a long time primarily with lipid disorders, but evidence from the past years has suggested that lipid-independent pathways are also involved. Recent research has demonstrated that the gastrointestinal microbiota has an impact on the development of atherosclerosis. Many clinical studies have revealed that there exist altered gut microbiota and increased inte...

The gut microbiota has appeared as an important rheostat for vascular inflammation in atherosclerosis

This emerging field of research is controlled by host-microbe interactions that may be therapeutically exploited in the future via @Gut_BMJ:

https://loom.ly/MP1bdWo

What is the link between #SIBO and acute pancreatitis?

This review updates the role of rifaximin, probiotics, butyrate, and others in reducing the complications of acute pancreatitis:

linkinghub.elsevier.com/retrieve/pii/S0261561425001621

What’s on your plate? In the future, your gut microbiota will shape your doctor’s dietary advice The gut microbiome influences how we respond to food and not all nutrients benefit us equally, something we’ve known for a while. A new review article delves into how our gut microbiome shapes the impact of diet on human health, leading to rethinking current nutrition guidelines.

🍅 A tomato doesn’t benefit everyone in the same way, so why recommend it to everyone?

Yolanda Sanz & @patrickveiga.bsky.social explain how gut microbiota science is shaping precision nutrition and challenging one-size-fits-all advice.

https://loom.ly/RaQ4mu8

A prebiotic blend may improve cognition in healthy older adults This article highlights new evidence on prebiotics improving cognition in older adults and explores implications for the microbiota-gut-brain axis.

A new randomised controlled trial in individuals aged over 60s showed that a prebiotic blend is well tolerated and may improve cognition compared with a placebo

Find out more:
https://www.gutmicrobiotaforhealth.com/a-prebiotic-blend-may-improve-cognition-in-healthy-older-adults/

Precision therapy in Crohn’s disease: Why the microbiome should be part of the equation Understanding how the gut microbiome changes precede and drive disease offers potential for developing personalized therapeutics

While current guideline-based therapies for #Crohn’s disease are immune-directed, recent advances in how #gutmicrobiome changes precede and drive disease offer potential for developing personalized therapeutics.
https://loom.ly/c_BJW8U

Resilience and brain health in global populations - Nature Medicine Unique biological, exposomal, economic and sociocultural factors shape resilience and brain health across the globe; this Review discusses underlying mechanisms of resilience, measurement approaches, operationalization and research gaps.

Promoting resilience or fighting pathology for enhancing well-being?

Understanding and promoting resilience could be a step towards enhancing well-being across and optimizingand optimizing human potential across the lifespan: https://loom.ly/oWxVYZE

Can your diet and gut microbiome be the key to healthy aging? Recent studies are beginning to reveal the potential role of different dietary patterns in shaping the gut microbiome composition and their association with aging and health outcomes.

Recent studies are beginning to reveal the potential role of different dietary patterns in shaping the gut microbiome composition and their association with aging and health outcomes.

Read the full article 👉 https://loom.ly/bgi_Gjo

A gut sense for a microbial pattern regulates feeding - Nature A study reveals a gut–brain sensory pathway through which the microbial component flagellin activates neuropod cells in the colon to signal the brain and reduce feeding in mice.

Gut–brain neural circuit forms the foundation of how the host adjusts its behavior by monitoring microbes.
New findings discovered PYY-labelled neuropod cells rapidly signal to the brain, through the vagus nerve, to regulate feeding behaviour
https://loom.ly/GmlEwQk

Scientists uncover common patterns in infant gut microbiome development on four continents A new study reveals that despite geographical and cultural differences, infants undergo similar microbial changes in their intestines.

🌍 Despite cultural and geographic differences, infants around the world show similar gut microbiome development patterns.

New research highlights a shared microbial trajectory in early life with global health implications.
https://loom.ly/X6tloTA

The gut microbiome–germline axis: Does a prospective father’s gut microbiota matter? Does a prospective father’s gut microbiota matter?

The gut microbiome–germline axis is an emerging but relevant area of microbiome research.

Does a prospective father’s gut microbiota matter?

via Science
www.science.org/doi/10.1126/...

Updating the evidence on ultra-processed foods and health - Nature Medicine A new analysis supports dietary guidelines to reduce the consumption of processed meat, sugar-sweetened beverages and trans-fatty acids — highlighting the need for a collaborative, meticulous health assessment framework for ultra-processed foods.

The impact of sugar-sweetened beverages, processed meat and trans fatty acids on type 2 diabetes, colon cancer and heart disease are partly mediated by the microbiome

https://www.nature.com/articles/s41591-025-03782-9

Host-microbiome relationship in depression: can human induced pluripotent stem cells play a role in unravelling mechanisms? - npj Biofilms and Microbiomes npj Biofilms and Microbiomes - Host-microbiome relationship in depression: can human induced pluripotent stem cells play a role in unravelling mechanisms?

Can human induced pluripotent stem cells play a role in unravelling mechanisms?
@crosellcardona.bsky.social, @kittelschneider.bsky.social & @jfcryan.bsky.social update their potential in advancing microbiota-gut-brain axis science and depression research
loom.ly/0esrUBY

Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects Fecal microbiota transplants (FMTs) may not always effectively restore small bowel microbiota due to regional differences in gut environments, potentially causing unintended effects on metabolism and ...

Regional microbial mismatches after fecal microbiota transfers can lead to unintended consequences and require rethinking of microbiome-based interventions

Find out more implications from bench to bedside:
www.cell.com/cell/abstrac...

Paving the way for microbiome-based therapy in clinical practice This article presents recent and compelling examples of microbiome-based treatments that are ripe for clinical adoption and discusses challenges and opportunities facing the field based on expert inte...

Where does microbiome-based medicine stand today, and where is it headed?

We explore five simulated clinical cases, featuring insights from @gilbertjacka.bsky.social and @katrinewhiteson.bsky.social

loom.ly/h7uGlx0

A role for microglia in mediating the microbiota–gut–brain axis - Nature Reviews Immunology This Perspective explores how the gut microbiota influences the function and heterogeneity of microglia, highlighting their roles in neurological and neuropsychiatric disorders, and discusses the therapeutic potential, challenges and clinical implications of targeting microbiota–microglia interactions.

What's new on gut–microglia communication for shaping microglia-related functions? This timely review addresses opportunities and clinical implications
@jfcryan.bsky.social @lilykeane.bsky.social
https://loom.ly/enYXCnc

Key advances in the gut microbiome during 2024 This article features key discoveries in gut microbiome research from 2024 selected by the Gut Microbiota for Health editorial team. Research highlights include basic, translational, and clinical microbiome research with significant implications for current and future research in the field.

What have been the latest key advances in gut microbiome research?

This research highlight includes basic, translational, and clinical microbiome research with significant implications for current and future research in the field:

https://loom.ly/nUqhZns

🧬 What if #gutmicrobiome research could be told as a thriller?
In Mission: Microbiome, Dr. @patrickveiga.bsky.social blends science & fiction to explore how microbes shape our health — and our future.

Discover the story behind the science in this GMFH interview:

Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway Brown et al. show that bacterial sphingolipids delivered by outer membrane vesicles (OMVs) persist within mammalian immune cells and promote IL-10 secretion via the mevalonate pathway. This sphingolip...

Bacterial sphingolipids in outer membrane vesicles promote anti-inflammatory responses in immune cells, through activation of the mevalonate

These findings from @ericmichbrown & colleagues might have implications for managing inflammatory conditions:

loom.ly/jhs462Q