Patrick Aouad

EMT and cancer: what clinicians should know - Nature Reviews Clinical Oncology Despite several decades of research that has revealed roles in the development and progression of many solid tumours, clinical translation of research targeting epithelial–mesenchymal transition (EMT)...

EMT and cancer: what clinicians should know doi.org/10.1038/s415...

23.07.2025 18:03 — 👍 1    🔁 1    💬 0    📌 0

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer - Nature Cancer Liang et al. study the impact of ERα antagonist/degraders against different Esr1 mutations in murine models and find that inhibition of mutant ERα induces lineage plasticity, which is also observed in...

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer doi.org/10.1038/s430...

28.04.2025 20:31 — 👍 4    🔁 3    💬 0    📌 0

The milk-producing structures, called Terminal Ductal Lobular Units (TDLUs), serve as the functional units of the human milk factory. Shown here is a section of #breast tissue stained with carmine alum, highlighting the epithelial structures of the mammary gland. Truly #fascinating! #Science

25.04.2025 18:45 — 👍 2    🔁 1    💬 0    📌 0

#Breast picture of the day or should I say painting?
Here's a 3D reconstruction of the human breast rendered into an artistic painting using AI tools! It really does look like something that belongs in a modern gallery. #Science #Art

24.04.2025 18:51 — 👍 5    🔁 1    💬 1    📌 0

This week’s 3D reconstruction of the human #breast highlights the #myoepithelial cells- the contractile cells that help squeeze the milk-producing luminal cells to release milk and nourish offspring. Truly fascinating! #Science #Art

21.04.2025 18:30 — 👍 5    🔁 1    💬 0    📌 0

Turning my Bluesky profile into a merge of #science 🔬 and #art 🎨: an exhibition featuring the beauty of the #breast through #microscopy. Starting with one of my favorites: 3D reconstruction of the human breast; Staining: Smooth muscle actin; Cells: Myoepithelial cells.

17.04.2025 21:10 — 👍 28    🔁 4    💬 1    📌 1

Tumor dormancy: EMT beyond invasion and metastasis More than two-thirds of cancer-related deaths are attributable to metastases. In some tumor types metastasis can occur up to 20 years after diagnosis and successful treatment of the primary tumor, a ...

Our review on Dormancy and EMT received enough views to be a Top Viewed and Cited Article. Read about it here: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle @wiley.com

16.04.2025 16:58 — 👍 3    🔁 1    💬 0    📌 0

Excited to attend this year’s GRS/C on mammary gland biology! Looking forward to connecting with experts in this inspiring field.

15.04.2025 20:28 — 👍 3    🔁 0    💬 0    📌 0