Valentine Comaills's Avatar

Valentine Comaills

@valcomaills.bsky.social

PI at University of Seville, cell biology dept. Spain 💃🏻. Chromosomal instability and cellular plasticity mostly in cancer. #newPI https://www.departamento.us.es/dbiocel/investigacion/ingeplascecan.htm

673 Followers  |  1,076 Following  |  22 Posts  |  Joined: 16.11.2024  |  2.2268

Latest posts by valcomaills.bsky.social on Bluesky

Vaya, ¿ porque solamente este candidato está presentado en la cuenta oficial de la universidad de Sevilla?? ? O NO es una cuenta oficial?

30.10.2025 20:34 — 👍 0    🔁 0    💬 0    📌 0
Introduction | Chromosomes in Crisis: From Chromosomal Instability to Catastrophes in Cancer Genomes | The European Association for Cancer Research

eacr.org/conference/c...

30.10.2025 14:51 — 👍 0    🔁 0    💬 0    📌 0
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😱🤩What a beautiful conference coming up (2026)! 😍
Chromosomes in crisis: From chromosomal Instability to Catastrophes in Cancer Genomes — join the EACR in Berlin, 3–5 Nov 2026!
Thanks to @helloeacr.bsky.social and the brilliant speakers for organizing this beauty!

30.10.2025 14:49 — 👍 0    🔁 0    💬 1    📌 0
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La #AEI @ageinves.bsky.social del #MICIU publica la resolución de los proyectos #PID2024. Lo principal:
- El número de solicitudes de proyectos sube un 1️⃣0️⃣%. Genial, ¿no?? La ciencia crece en España, ¿no?? 😀

Pues no... 😕
- La financiación total se estanca.
- La financiación por proyecto baja.

29.07.2025 15:33 — 👍 22    🔁 13    💬 0    📌 2
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Ongoing genome doubling shapes evolvability and immunity in ovarian cancer - Nature A single-cell sequencing study using more than 30,000 tumour genomes from human ovarian cancers shows that whole-genome doubling is an ongoing mutational process that drives tumour evolution and disrupts immunity.

Nature research paper: Ongoing genome doubling shapes evolvability and immunity in ovarian cancer

go.nature.com/40qLLcJ

21.07.2025 17:47 — 👍 18    🔁 3    💬 0    📌 1

Congratulations 🎉🎉👏🏻👏🏻👏🏻

30.06.2025 10:52 — 👍 0    🔁 0    💬 0    📌 0
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Great discussion at the #EACR2025. Thanks to everyone who came to my poster yesterday for the feedback! @valcomaills.bsky.social @unisevilla.bsky.social

18.06.2025 17:03 — 👍 3    🔁 1    💬 0    📌 0
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So much fun at Lisbon for the #eacr2025! Former and current investigators from @unisevilla.bsky.social 💃🏻👩🏻‍🔬 @helloeacr.bsky.social @livialopez.bsky.social and Sonia Silva from I3S.

16.06.2025 20:38 — 👍 5    🔁 1    💬 0    📌 0
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Andy Moore @hhmijanelia.bsky.social created this video showing a cytoskeletal mechanism called an actin wave in a so-called HeLa cell. In orange are the actin filaments and in blue are the mitochondria, some of which appear to move with or be shifted by the active wave.

03.06.2025 15:33 — 👍 26    🔁 8    💬 1    📌 0
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Inkscape plugin to rescale figures without distorting the text, and other useful features!
github.com/burghoff/Sci...

02.06.2025 12:15 — 👍 152    🔁 46    💬 6    📌 3
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Huge shoutout to Javi (Fzco Javier Mendoza León), our Ph.D. student, for being awarded the AECC Predoctoral Fellowship 2025-Sevilla! 🎉 We hit the jackpot having you on the team!
Thank you so much @contracancerinv.bsky.social with @unisevilla.bsky.social
¡Enhorabuena a Javi! 👏

23.04.2025 14:42 — 👍 6    🔁 1    💬 0    📌 0

My gosh, what an incredible amount of work! So great to see those results coming through - both in your model and the TCGA data. Huge congrats!

15.04.2025 12:24 — 👍 1    🔁 0    💬 0    📌 0
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Evolutionary fingerprints of epithelial-to-mesenchymal transition - Nature Malignant cells with mesenchymal features display increased chromatin accessibility, particularly in the pericentromeric and centromeric regions, in turn resulting in delayed mitosis and catastrophic ...

new out in @nature.com www.nature.com/articles/s41...

06.03.2025 08:26 — 👍 16    🔁 7    💬 7    📌 0
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The 7 new #CancerGrandChallenges have just been announced! Read about them now in Cancer Discovery: doi.org/10.1158/2159...
@cancergrand.bsky.social

05.03.2025 15:32 — 👍 20    🔁 7    💬 0    📌 1
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Ayer estuve en el II Encuentro de Investigadores AECC! 🔬💙
Gracias ♥️ @ContraCancerEs, @contracancerINV y voluntarios por hacerlo posible. Un día increíble para conectar, compartir ideas y recordar que nuestra investigación tiene un impacto real en los pacientes. 🚀 #encuentroinvestigadoresaecc!

05.03.2025 15:09 — 👍 1    🔁 0    💬 0    📌 0

So beautiful to see...

28.02.2025 08:22 — 👍 0    🔁 0    💬 0    📌 0
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Bespoke vaccines can elicit long-lived immune activity against pancreatic cancer T cells induced by personalized pancreatic-cancer vaccines last for years.

This study found that RNA vaccines can induce an immune response in patients with pancreatic cancer

https://go.nature.com/4hI3XVL

24.02.2025 11:46 — 👍 78    🔁 26    💬 0    📌 2
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Hello, Bluesky! ☀️

We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.

Follow us for updates on ERC funding, research policy, and our grantees' discoveries.

07.02.2025 08:16 — 👍 1132    🔁 380    💬 42    📌 30
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"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here: www.nature.com/articles/s41...

06.02.2025 16:02 — 👍 354    🔁 104    💬 9    📌 7
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A neoantigen vaccine generates antitumour immunity in renal cell carcinoma - Nature A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patie...

Personalized cancer vaccines are a game-changer! The results are incredibly promising—so encouraging to see!

www.nature.com/articles/s41...

06.02.2025 15:31 — 👍 1    🔁 0    💬 0    📌 0

Lovely talk! Thanks for the organization of this meeting!

30.01.2025 13:58 — 👍 1    🔁 0    💬 0    📌 0

Yeahhhh convocatoria de consolidación investigadora 2025 en junio!

27.01.2025 12:23 — 👍 2    🔁 0    💬 0    📌 0
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Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

Big if true: do cancer cells transfer mutated mitochondria into tumor infiltrating lymphocytes to impair their function? mtDNA is challenging to work with, so looking forward to see this finding confirmed. But cool concept and big congrats to the authors!

www.nature.com/articles/s41...

22.01.2025 19:41 — 👍 10    🔁 2    💬 0    📌 0
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Bluesky Starter Packs - Bluesky Directory Browse a list of Bluesky Starter Packs. Discover and connect with your community on Bluesky

Busca tus gentes de interés blueskydirectory.com/starter-pack...

22.01.2025 07:23 — 👍 1    🔁 0    💬 0    📌 0

Todo igual pero sin publicidades y con muchas más visibilidad a los investigadores.
Hay tambien 'starting package' para seguir gente de tu campo o interés (tipo nature editors). Mola!

22.01.2025 07:22 — 👍 1    🔁 0    💬 0    📌 0
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Registration is now OPEN for the cancer research community to join us for the EACR 2025 Congress! 🥳

Don't miss the opportunity to take advantage of our discounted early registration rate to attend, available until 28 April.

2025.eacr.org

07.01.2025 11:20 — 👍 17    🔁 11    💬 0    📌 0
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Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin

08.01.2025 12:14 — 👍 149    🔁 40    💬 8    📌 5

🔥🔥👇🏻👇🏻

03.01.2025 11:54 — 👍 1    🔁 1    💬 0    📌 0
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Engineered extrachromosomal oncogene amplifications promote tumorigenesis - Nature Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene a...

🧪1/ 🚨New paper on ecDNAs from our lab!
We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇
www.nature.com/articles/s41...

18.12.2024 16:54 — 👍 117    🔁 43    💬 12    📌 8

One of the biggest questions we get is when will our journals be here. We thank you for your patience.

You can now follow our journals with this starter pack!

18.12.2024 14:57 — 👍 404    🔁 152    💬 20    📌 33

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