MathOnco

Integrated Mathematical Oncology The Integrated Mathematical Oncology Major consists of focused training in mathematical modeling for cancer biology and clinical oncology problems.

Just a few more days to apply to the fully-funded #PhD program in #MathOnco at @moffittnews.bsky.social . Deadline is December 1st!

www.moffitt.org/education/re...

Just going around some of the groups working at the @moffittnews.bsky.social @mathonco.bsky.social #MoffittIMO 2025 and the energy is palpable! I think the judges on Friday morning are going to be blown away by the ideas these guys are working on!

Day 3: Trying to keep the momentum! Subgroup tasks ongoing! @mathonco.bsky.social @moffittnews.bsky.social @sandyanderson.bsky.social

Dr Mansilla-Soto giving #TeamBlue a 10-min crash course in #immunology ! @mathonco.bsky.social @sandyanderson.bsky.social @moffittnews.bsky.social

Day 1: Say hi to #TeamBlue! Preliminary discussions on-going. Cheers to our team leads: Renee Brady-Nicholls,PhD, Jorge Mansilla-Soto,PhD and Nicholas Champion, MD
@mathonco.bsky.social @moffittnews.bsky.social

Speed dating..but for scientists! - - -> IMO version! 😊 @mathonco.bsky.social

Welcome session ongoing with @sandyanderson.bsky.social giving us the history of the famous IMO Workshop @mathonco.bsky.social from year 1 to 12!

Last speaker at #MathOnco25 is our own @mathonco.bsky.social Jeffrey West that provides a study of the #mathonco literature to produce this definition of MathOnco: the use of interpretable models to understand and improve cancer therapy

Well, #IMO retreat is underway now and here is our very own
@sandyanderson.bsky.social
describing some of the changes and accomplishments at
@mathonco.bsky.social
since our last retreat in 2018

Drug-induced proliferation curves preserve convexity mathematical-oncology.org

#Antifragility in #cancer #treatments one step closer to clinical reality. By Jeff West writing on his #MathOnco research with @andriy-marusyk.bsky.social @sandyanderson.bsky.social et al

Excited to announce that registration for the 13th
@mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!

Lots of great research from the #blackboard to the #bedside at @mathonco.bsky.social

Interested in doing a PhD in #MatOnco next year? Our department at @moffittnews.bsky.social is a great place to do research and we offer fully-paid tuition and fees. Apply before the deadline 12/1 at Moffitt.org/CancerPhD

Then our very own Jill Gallaher discusses our ongoing @evoltherapy.bsky.social clinical trial with @genentech.bsky.social on, Adaptive therapy in advanced basal cell carcinoma driven by imaging and predictive mathematical. #AndersonLab @mathonco.bsky.social @moffittnews.bsky.social

Probably not standard in many PhD courses (that should change!) but our @moffittnews.bsky.social @mathonco.bsky.social students had a lecture on science communication and outreach by the one and only @parmvir.com @scientistsinc.org

Evolutionary theory tells us that to cure #ovariancancer we need to target it when its most vulnerable – at the end of 1st-line tx. The challenge: that’s also when treatment-induced toxicity is greatest.
Check out our new #IMO12 pre-print with 3 ideas how to tackle this! @mathonco.bsky.social

We had the pleasure of hosting a high school student as part of @mathonco.bsky.social @moffittnews.bsky.social HIP-IMO program led by Dr Renee Brady
www.moffitt.org/education/re...

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories We developed a plain text modeling language—a cell behavior hypothesis grammar—to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues...

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n

www.cell.com/cell/fulltex...

@jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Submit your abstract for #MathOnco25 in Tampa this October!

Discovering mechanisms of response via CSI (Cancer Systems Immunology) mathematical-oncology.org

In this week's post Jesse Kreger (@adamlmaclean.bsky.social‬) discusses his latest work in #cancer #systems #immunology together with Edgar Gonzalez to study the mechanisms of response of breast cancer to #checkPointInhibitors

It was a great meeting and made me more optimistic about the role of AI in #MathOnco research

Yesterday's #mathonco minisymp with @mathonco.bsky.social @moffittnews.bsky.social's chair and friend @sandyanderson.bsky.social presenting models that capture patient data and help us to understand how to improve treatment schedules in a clinically translatable way

Former HAL developer and @mathonco.bsky.social student, Rafael Bravo now with @utaustin.bsky.social presents new work on: "Testing the feasibility of estimating the migration to proliferation rate ratio in glioblastoma from single time-point MRI data" #SMB2025

Next up is our very own @mathonco.bsky.social faculty @rejniaklab.bsky.social presenting, "Using tumor histology to analyze cancer immunotherapies with the agent-based micropharamacology model" #SMB2025 @moffittnews.bsky.social

Closing this session is another one of our @mathonco.bsky.social faculty, @cancerevo.org David Basanta: "Calibrating a Spatial Agent-Based Model of Multiple Myeloma Using In Vivo Data to Predict Immunotherapy Response" #SMB2025 @moffittnews.bsky.social

Mary

Why Math modeling

atherosclerotic plaques

Plenary this morning @smbmathbiology.bsky.social by Mary Myerscough (U of Sydney) modeling atherosclerotic plaques. Included a great slide showing why #MathModeling. The process of formulating models is key (even if it not always leads to a publication).
#SMB2025

The Future of Mathematical Oncology in the Age of AI mathematical-oncology.org

Over a month ago a bunch of #MathOnco and #AIOnco researchers got together in Syracuse to discuss how #AI may and may not change the field. Here are some thoughts in a collective effort led by @rrockne.bsky.social:

@mathonco.bsky.social catchup vibes #IMO #mathematicalOncology #MindUpdate #Mehtods&Tools #BeanberryCoffeeKingston

Optimal dosing of anti-cancer drug treatment under drug-induced plasticity mathematical-oncology.org

A behind-the-paper post by
Einar Gunnarsson: Optimal #dosing of anti-cancer drug treatment under drug-induced #plasticity

A massive @mathonco.bsky.social congratulations to Dr. Weh @gosiaweh.bsky.social on successfully defending her PhD. Also a shoutout to both her advisors @cancerevo.org and Andriy Marusyk @moffittnews.bsky.social