Immunotherapy fails at curing heterogeneous cancers. Why? Modeling and clinical data suggest a limit to tumor heterogeneity, beyond which T cells fail at controlling highly-diverse tumors. Can we take advantage of this limit? @ricardsole.bsky.social royalsocietypublishing.org/doi/full/10....
02.06.2025 14:59 — 👍 8 🔁 0 💬 0 📌 0
Our work is based on two great recent articles that strongly impacted the way I think about complexity in ecology. Inspiring! @changyuchang.bsky.social @asanchezlab.bsky.social
22.05.2025 05:42 — 👍 6 🔁 2 💬 0 📌 0
Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests www.biorxiv.org/content/10.1...
20.05.2025 13:16 — 👍 89 🔁 31 💬 2 📌 1
Congrats Lisa!!!
11.03.2025 13:08 — 👍 1 🔁 0 💬 0 📌 0
I've used this paper quite a lot and we've discussed with @ricardsole.bsky.social and @vmaull.bsky.social often. Great and useful work!
31.01.2025 08:20 — 👍 2 🔁 0 💬 0 📌 0
High burden and pervasive positive selection of somatic mutations in normal human skin
Sun-exposed but physiologically normal human skin harbors an unexpectedly high number of cancer-causing mutations. [Also see Perspective by Brash]
Super interesting! reminds me of the work by I. Martincorena, finding that epidermic cells can remain healthy even when carrying hundreds of cancer mutations www.science.org/doi/abs/10.1...
Maybe genome alterations are not enough and other ecological dynamics play a role?
27.01.2025 09:27 — 👍 2 🔁 0 💬 1 📌 0
Thanks! In the paper we mention some ongoing efforts in that direction, but it does still feel a bit futuristic. On my side, I am very interested on the cancer-immune-microbiome ecosystem that you work in! Would love to chat about it at some point :D
22.01.2025 10:11 — 👍 2 🔁 0 💬 0 📌 0
Tumors harbor hundreds of different cell types that compete and cooperate, mirroring a natural ecosystem. Can we model cancer as a complex ecosystem of many interacting species?
An honor to work w/ @ricardsole.bsky.social and Sandy Anderson while bringing in recent work in ecology with Sonia Kéfi!
13.01.2025 11:06 — 👍 29 🔁 6 💬 1 📌 1
Astrofísico
Santiago - Chile
Professor, University of Geneva. We study Enterococcal biofilms, pathogenesis, and AMR. Formerly @KimInSingapore 🌴.
https://kimberlyklinelab.com/
Control Systems Engineer. Visiting fellow affiliated with NIMH.
Postdoc @University of Turku, 🇫🇮 | animal behaviour, ecology and climate change | Working on Asian elephants, focusing on social behaviour, functional ecology & demography 🐘🌿🌳
Past: PhD @JNCASR and postdoc@NCBS, 🇮🇳.
https://linktr.ee/hansraj.g
PostDoc researcher
Behavioral ecology, phenotypes evolution, sexual selection, social behaviour, coloration, cognition, personality
PhD (she/her)
PhD Student at ANU studying foraging and habitat use in the superb fairy-wren 🐦
Wildlife photographer 🌱
IG: fran_x_photography
MRes Animal Behaviour, MSci Bioacoustics, BSc Neuroscience
Long-term study of superb fairywrens in the Australian National Botanic Gardens by researchers at the Australian National University #superbfairywren #SFW_ANU
Head of the department of Evolutionary Animal Ecology @ University of Bayreuth | Professor | #firstgen | mother | loves burying beetles |interested in the evolution of family life and chemical communication
Professor Bristol uni Biological Sciences. Lots of #fishsci #behaviour #rstats #collectivebehaviour #predators. Grants Secretary for @asab.org
PhD candidate at Laval University | Behavioral ecology | predator-prey interactions | animal movement | stress physiology | arctic ecosystems
www.researchgate.net/profile/Frederic-Dulude-De-Broin
To access papers
fredericddb.github.io/get-me-the-pdf
🦜 Researcher at @wildanimalinitv.bsky.social
🐒 #AnimalWelfare Postdoc at @newcastleuni.bsky.social
Opinions are my own (she/her)
Lecturer at the University of Bristol. Bumblebees, Animal cognition, Behaviour, Ecology, Conservation, Pesticides, Husband, Dad. He/him. 🐝
https://siviterharry.wixsite.com/harrysiviter
PhD in blue tits' behavioral ecology at CEFE (CNRS, Montpellier 🇨🇵) | Your typical queer vegan woke feminist with an extra nerdy/weeb flavour. Also a dog mom and a birding 🦅/ gaming🎮🎲 / metal🤘 enthusiast.
Evolution; animal behaviour; animal culture; human cognitive evolution; niche construction; anti-racism
#evolution #evodevo #philbio #philsci #animalculture #animalbehavior
PhD student | Evolutionary Biology | Climate change and sexual selection | Animal Behaviour | Heateaves | Decolonising | QUADRATdtp | University of Aberdeen | opinions are my own | she/her
Assistant Professor at West Texas A&M University. Interested in phenotypic plasticity, urban evolution & ecology, and animal behavior.
Assistant Professor @psychualberta.bsky.social 🇨🇦 | PI: The Seasonal and Social Neuroendocrinology (SeaSoN) Lab @ualberta.bsky.social | social and seasonal regulation of behavioral plasticity in cichlids 🐟🧠🧬 | she/her
Evolutionary ecologist interested in early-life and parental effects, climate change, infectious diseases. Likes insects, theory and comparative studies.
Leads EVE lab, Bristol UK www.evelab.org
UKRI Future Leaders Fellow, academic mama, from Zimbabwe
Provoking equestrians by asking horses for consent 🥕 Science & ethics based trainer
Chicken welfare and genetics researcher
Conservation biologist and behavioural ecologist. Treasurer of Scientists for Labour. Postdoc at @durhamanthropology.bsky.social, DPhil from @biology.ox.ac.uk