Unnati Sonawala

Interspecific hybridization was key to tuberization. Thank you hybrid speciation for the world's 5th most important food crop 🥔

How do enhancer-gene contacts relate to transcription activation? In mouse embryonic stem cells, a combo of STED, oligoFISH & RNA FISH shows that 3% of Dppa3 alleles transcribe. For these, enhancers and promoters come closer (panel E). Stumberger ... Leonhardt & Harz www.biorxiv.org/content/10.1...

Just the tip of the iceberg...more to come on this topic!

Congratulations to Laura Mancera-Miranda for her first scientific paper, and best of luck for her upcoming PhD dissertation defence!

doi.org/10.1002/mbo3...

TODAY. 15:15 @ Room P&Q #2025ISMPMI

Please don't miss it! A great session on the spatial and temporal regulation of plant–microbe interactions, hosted by @uprogress.bsky.social and @tatsuyanobori.bsky.social Many attractive talks, including our latest research presented by @crbeuzon.bsky.social

#ISMPMI2025 #MicroSky #PlantScience

John Matthew McDowell: A Visionary Leader in Molecular Oomycete-Plant Interactions and a Wonderful Mentor and Friend to Many | Molecular Plant-Microbe Interactions®

In memory of our dear colleague, John McDowell, who left us all too early. RIP. doi.org/10.1094/MPMI...

John Matthew McDowell: A Visionary Leader in Molecular Oomycete-Plant Interactions and a Wonderful Mentor and Friend to Many | Molecular Plant-Microbe Interactions®

We lost a Grangle family member, a friend, and a visionary scientist. “A note from Jeff Dangl: John McDowell was a former MPMI Editor and great membr of our community and that it is apt that his memory be recognized at the current #2025ISMPMI
nam12.safelinks.protection.outlook.com?url=https%3A...

🪱 Calling all Early-Career Nematologists:
Registration for #VNC2025 is NOW OPEN! 🎉

If you are MSc student, PhD candidate, or postdoc working in nematology, Register and submit your abstract.

Register here👉 lnkd.in/dzTRsK7z

⏰ Registration closes September 10th!!!

Mark you calendars! We are back this November #VNC2025

These are absolute treasures! All the best at Heidelberg!

Cell-type-specific execution of effector-triggered immunity

Our new preprint is online, 1 July⬇️

With @himanshuchhillar.bsky.social @leonardojo.bsky.social Amey Redkar @kaisakajala.bsky.social @jonathandgjones.bsky.social

For early readers & community feedback🙏🏼

#openscience @erc.europa.eu

My sister is finishing her endocrinology residency (proud sister moment 😎). Instead of wrestling with Word to write equations for her thesis, I offered to help with LaTeX. Writing in LaTeX is one of the most rewarding things I’ve taught myself, but this might be its shiniest use yet! #LaTeX

Really interesting study - thank you for sharing! What are your thoughts on it?
I wonder 1) Is there a way to better manage the 'pivot penalty'? and 2)What if a longer time frame than 10 years is considered?

#ISMPMI2025 attendees!

Bookmark our concurrent session co-organized with @uprogress.bsky.social featuring exciting talks on the spatial and temporal regulation of plant–microbe interactions.

We have 3 invited speakers: Feng Zhou, @lluginbuehl.bsky.social @type3lab.bsky.social

and…

🌐 Online symposium of the Society of Nematologists
📌 "#Nematodes on the move: building resilience and sustainability through international collaboration and better policies"
🔎 Program available at drive.google.com/drive/folder...
📥 Register here 👉 iica.zoom.us/webinar/regi...

Thank you, @david1822.bsky.social!

Very glad to have won one of the Postdoc Innovation Awards and excited to see the final outcome. Stay tuned!

🌲 In just 90 seconds, I distill the relevance and impact of my PhD
▶️ Watch the full video 👉 youtu.be/lLtgd9EE1nw?...
#PinewoodNematode #PineWiltDisease #Esteya #Biocontrol

A wheat tandem kinase activates an NLR to trigger immunity The role of nucleotide-binding leucine-rich repeat (NLR) receptors in plant immunity is well studied, but the function of a class of tandem kinases (TKs) that confer disease resistance in wheat and ba...

2 papers in @science.org this week uncover wheat tandem kinase function. Working in parallel, the authors of each paper show that two different tandem kinases converge to activate the same NLR!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

#PlantScience

Deadline for abstract submission has been extended to 4th of April! Don't forget to submit your abstracts for the PPN mini-symposium at the Hydra Helminths conference this September 🗒️🌱

A wheat tandem kinase and NLR pair confers resistance to multiple fungal pathogens Tandem kinase proteins underlie the innate immune systems of cereal plants, but how they initiate plant immune responses remains unclear. This report identifies wheat protein wheat tandem NBD 1 (WTN1)...

Oh yes. This is new. Non-NLR and NLR pair for immune sensor and executor!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

Enjoying reading this paper with excellent use of single cell seq along with reporter lines and lineage tracing to understand secondary growth cell identity in Arabidopsis roots.

Fascinating paper on fern immunity and host-microbe interactions! 🦠🌿 They uncover a new class of NLRs (disN-NLRs) with disordered N-terms. Interestingly, many ferns lack NPR1, but conservation of SARD1 and SARD4 hints at alternative SAR mechanisms.

This perspective article captures the essence of the dream - all the questions we could ask and find answers to if we could perform single-molecule protein sequencing. And describes how we may be close to realizing it.

Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇

Cool study! Plant defense usually means looking 'not-diseased,' making these genes invisible until lost. But here, the authors found that a 254bp transposon in bHLH35 boosts anthocyanins, visually camouflaging the plant from herbivores. A defense you can see!

The SUbventral-Gland Regulator (SUGR-1) of nematode virulence | PNAS Pathogens must precisely tailor their gene expression to cause infection. However, a signaling cascade from host signal to effector production has ...

Go SUGR-1 >> The SUbventral-Gland Regulator (SUGR-1) of nematode virulence | Funded by the EU 🇪🇺 | Kudos to all authors 💪

Reminder to submit your abstracts before the approaching deadline ⏰

Assembly and annotation of Solanum dulcamara and Solanum nigrum plant genomes, two nightshades with different susceptibilities to Ralstonia solanacearum https://www.biorxiv.org/content/10.1101/2025.02.12.637948v1

Check out our new study! We show that Arabidopsis uses the EDS1-SAG101-NRG1 node to trigger rapid yet contained cell death. Key finding: NRG1C variant regulates this process by competing with functional NRG1s. Amazing collaboration between Jijie Chai and Parker Labs.
www.nature.com/articles/s41...