Canals Lab

Thank you Aldo!
We learnt that a triplet isn’t just jazz, it can set the hidden rhythm of a neuronal ensemble!

Today we had the pleasure of hosting Dr. Aldo Genovesio from @uniupo.bsky.social at our #SeminarsIN with his talk: “What do we learn by shifting focus from neurons to neuronal assemblies?”
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es

Inspiring work. Thank you Jaime!

Israel ha detenido al director de orquesta israelí Ilan Volkov después de condenar las acciones de su país en Gaza durante un concierto en Londres.
“Detengan el genocidio. Lo está destrozando todo. Párenlo ya”.

🔥New study published in PLoS Computational Biology, led by Santiago Canals @canalslab.bsky.social at @neuroalc.bsky.social and @claudiomirasso.bsky.social at @ifisc.uib-csic.es , reveals how brain rhythms flexibly route information.
More info 👇
in.umh-csic.es/en/articulos...

Huge thanks to:
🔹 David Moratal - @upv.es
🔹 @plopezlarrubia.bsky.social - @iibm-csic-uam.bsky.social
🔹 Mohamed Selim - @uniofnottingham.bsky.social
🔹 From @neuroalc.bsky.social: Santiago Canals @canalslab.bsky.social, Silvia De Santis @desantislab.bsky.social & @maxeggl.bsky.social 🙌

Happy to join the 2nd NeurotechEU Summer School on Preclinical Magnetic Resonance Imaging and Spectroscopy, presenting on #MetabolomicNMR in beautiful #Alicante!

🎉 Today we celebrated the 18th IN Progress Report Workshop at @neuroalc.bsky.social!
Leaders from 7 of our 8 scientific programs shared their latest research, alongside posters by our 2nd-year PhD students.
Here's a quick recap 🧵👇
#Neuroscience #jornadasIN2025
@csic.es @dicv.csic.es @umh.es

La junta de las becas Fulbright dimite en pleno por la interferencia del Gobierno de Trump “Inyectar política y mandatos ideológicos en el programa viola la letra y el espíritu de la ley”, denuncian sus miembros

elpais.com/internaciona...

👏🏻👏🏻

Israel is accused of the gravest war crimes in Gaza Distinguished lawyers, senior humanitarians and diplomats tell Jeremy Bowen why they are increasingly concerned about the catastrophe inside Gaza

Jeremy Bowen's long, measured, objective, but ultimately entirely clear and conclusive essay on Israeli war crimes. As Jonathan Sumption puts it:

"These things make genocide the most plausible explanation for what is now happening."

www.bbc.co.uk/news/article...

a chart showing power consumption of big tech companies

hey lovelies, I finally got around to publicly sharing my compilation of big tech energy and emissions data. I'll be using it in articles, posts etc but it's yours too, free to use (w/ attribution is nice)

ketanjoshi.co/2025/05/23/d...

Thank you to all collaborators
@wetuad.bsky.social @claudiomirasso.bsky.social @neuroalc.bsky.social @csic.es @umh.es @ifisc.uib-csic.es

#Neuroscience #Memory #DBS #CognitiveFlexibility #Neuroimaging #NeuroTech

NAc-DBS selectively enhances memory updating without effect on retrieval Neuropsychopharmacology - NAc-DBS selectively enhances memory updating without effect on retrieval

If you are interested, find the full article here: rdcu.be/enT5X

Methodological highlight:
We developed a novel spatial task that dissociates encoding vs. retrieval within-subjects using a high-dimensional behavioral readout.

Standard memory tests might have missed this.

Why does this matter?
Memory flexibility is key in psychiatric disorders characterized by cognitive rigidity.

Our study provides a mechanistic foundation for using NAc-DBS to improve cognitive flexibility.

fMRI revealed that NAc-DBS activates a broad memory-related brain network: septum, entorhinal & insular cortices—with some degree of adaptation but not desensitization over time.

We propose it mimics a dopaminergic “novelty” signal, reinforcing the encoding of new information.

Using high-resolution behavioral analysis & fMRI in rats, we dissected memory into short-term, long-term, encoding, and retrieval.

📌 Key finding: NAc-DBS enhances the encoding of new long-term memories—not short-term memory or recall.

Why NAc-DBS?
NAc-DBS is already used to treat psychiatric conditions like OCD and depression. But it could also boost memory. We designed a new spatial navigation task to find out.

New Study Out Now!
We investigated how deep brain stimulation (DBS) of the nucleus accumbens (NAc) affects memory. www.nature.com/npp/

Title: NAc-DBS selectively enhances memory updating without effect on retrieval
👇 THREAD 👇

It was a real treat to host @franzelab.bsky.social. Such exciting and thought provoking findings!! Thanks for your visit 👏🏻👏🏻

Mañana, en la jornada 'El juego de apuestas: un problema de salud pública', se presentará el libro 'Juego de apuestas y publicidad', coordinado por Santiago Canals @canalslab.bsky.social y Daniel Lloret @umh.es .
Una obra clave para entender el impacto de la publicidad en el juego📚 @csic.es

El @neuroalc.bsky.social y la Cátedra de Neurobiología Remedios Caro Almela organizan la mesa redonda del Ciclo Cerebro y Sociedad 'El arte de entender el cerebro: Cajal y las Neurociencias🧠
Sesión abierta a todos los públicos‼️ #SemanaCerebroIN
Os esperamos en el Club Información #Alicante

Today we celebrate #InternationalWomensDay. A privilege to work in a research center with such amazing colleagues!

New from the lab!! 👉🏼 authors.elsevier.com/a/1kgT43BtfH... 📝 @cellpress.bsky.social We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Juan Gallego @juangallego.bsky.social

Today, Dr. Javier Fernández-Martínez from Instituto Biofisika UPV/EHU - CSIC offered us a fantastic #SeminarsIN about the structural and functional mapping of the nuclear pore complex.
Great talk, thank you! 👏👏
@csic.es @umh.es @morantelab.bsky.social

Great work by López-Bendito Lab on sensory cortex reorganization. Congratulations to the team!

Myelin Quantification Using Ultrashort Echo Time Magnetization Transfer Ratio in a Mouse Model of Traumatic Brain Injury
onlinelibrary.wiley.com/doi/epdf/10....

#neuroimaging #neurology #neuroskyence #radiology #myelin #MRI #traumaticbraininjury

Bai1 mGL-CT-IRES-Cre
GPRC5A- EGFP-CT-IRES-ERT2-CRE
Gprc5b-IRES-CRE
Mtnr1b-mCherry-Ct-IRES-FlpO
ADGRG3-EGFP-CT-IRES-CRE
Bai3_EGFP
Bai3_IRES-Cre
Hcar1_EGFP_Ct_IRES_ECE
Adgrb2_EGFP_Ct_IRES_ECE
Mtnr1a_EGFP_Ct_IRES_ECE

Please RT
#neuroskyence
#science

Here's a cool new study from @dulaclab.bsky.social to cleanse your timeline: They show that a mouse's brain maintains an animal's need for social interaction in the same way that it tracks hunger, thirst and sleep! 🧪 #neuroskyence