Kha Tram, Ph.D

Autoimmune Disease, Transformed?

Dozens of clinical trials are underway trying to change the landscape of autoimmune disease therapy:

Computational Assessment of Circularization Impact on Saxitoxin G-quadruplex Aptamer Performance

Figure 1

Figure 2

Figure 3

Computational Assessment of Circularization Impact on Saxitoxin G-quadruplex Aptamer Performance [new]
Comp. method guides saxitoxin aptamer circ., maintaining/improving affinity by predicting struct. impact.

AI Simulates Lungs for IPF Drug plus: Dr. Oz Backs AI Health Bots

This week's AI Healthcare Roundup:

• AI Simulates Lungs for IPF Drug
• First AI Surgical Guide Cleared
• Dr. Oz Backs AI Health Bots

plus: 10 funded Startup this week

#AI #AIHealthcare #AINews

www.aiinlabcoat.com/p/ai-simulat...

Mayo Clinic taps former Biden administration official to oversee its use of AI Exclusive: Micky Tripathi, former top HHS official, to join Mayo Clinic as a senior executive overseeing implementation of AI.

Scoop: Former Biden health IT head Micky Tripathi is going to Mayo Clinic to oversee AI

from @caseyross.bsky.social @statnews.com

🖥️🩺

www.statnews.com/2025/04/10/m...

How Far Has AI Drug Design Come? plus: What COVID Taught Us About AI

This week's AI Healthcare Roundup:

• How Far Has AI Drug Design Come?
• What COVID Taught Us About AI
• Are AI Therapy Bots Safe for Kids

plus: 12 funded Startup this week

#AI #AIHealthcare #AINews

www.aiinlabcoat.com/p/how-far-ha...

Trump administration orders NIH to eliminate $2.6 billion in federal contracts At a chaotic time, the NIH is given a deadline of April 8 to make a 35% cut in services that may include specimen storage, genetic counseling, and administration.

Another $2.6 billion in cuts to NIH are coming by next Tuesday
www.statnews.com/2025/04/03/n... The shredded image fits

AI Drug Development: Blurring Lines Between Innovation and Reality in 2025 AI revolutionizes drug discovery, cutting development timelines and costs. Explore the blurred lines of "AI-developed" drugs and their potential to transform pharmaceutical research.

Over the past few months, I’ve been tracking and curating a database of AI-involved drug candidates, 380+ so far across 88 companies.

It’s a mix of repurposed drugs, AI-designed molecules, and smarter clinical trials.

(Link to database in article)

www.aiinlabcoat.com/p/what-makes...

Detect Lung Disease with AI Breath Test plus: Who's Liable for AI Medical Errors?

This week's AI Healthcare Roundup:

• Detect Lung Disease with AI Breath Test
• Who's Liable for AI Medical Errors?
• EU Debates AI Regulation Limits

plus: 12 funded Startup this week

#AI #AIhealthcare #AInews

www.aiinlabcoat.com/p/detect-lun...

The United States has lost its traditional allies, gotten in bed with Russia and is on the verge of becoming a police state, with inflation about to go up, massively, and people over on X are … posting Studio Ghibli memes.

logos of the 12 companies reviewed

The business of promoting longevity and healthspan through extensive medical testing. A review of 12 companies and why this is a flawed, expensive model without evidence.
erictopol.substack.com/p/the-busine...

Mammograms Now Screen Heart Health plus: FDA Clears AI for Robotic Surgery

This week's AI Healthcare Roundup:

• Mammograms Now Screen Heart Health
• FDA Clears AI for Robotic Surgery
• AI Claim Denials Under DOJ Watch

plus: 11 funded Startup this week

#AI #AIhealthcare #AInews

www.aiinlabcoat.com/p/mammograms...

A nonsensical threat to:
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.

Evaluating AI for Suicide Response plus: AI Digital Twins for Trans Patients

This week's AI Healthcare Roundup:

• Evaluating AI for Suicide Response
• AI Digital Twins for Trans Patients
• AI and BCI Restore Speech in ALS

plus: 12 funded Startup this week

#AI #AIhealthcare #AInews

www.aiinlabcoat.com/p/evaluating...

Bioscience Funding Confusion Threatens U.S. Innovation ‘With the current turmoil, China could surpass the U.S. in the near future,’ Nobel Prize winner David Baker warns.

Nobel laureate David Baker on US cutting science funding:

"With the current turmoil, China could surpass the U.S. in the near future, and we may be buying advanced medicines and other scientific-research-intensive products from Chinese companies in the not too distant future."
🧪🖥️🩺🧬

The State of Healthcare AI: February 2025's Latest Investment and Industry Insights A breakdown of February’s AI healthcare funding, policy changes, and emerging trends shaping the industry.

AI healthcare startups raised $1.5B in February, but there’s more to the story.

• U.S. deregulation vs. stricter state rules
• Europe’s AI Act enforcement kicks in
• China’s open-source brings competition
• India ramps up AI investment

Here’s my breakdown for this month. 👇

bit.ly/3R8h9aG

AI Spots Depression via Wi-Fi Motion Sensor plus: Connecticut Fights AI in Health Insurance

This week's AI Healthcare Roundup:

• AI Spots Depression via Wi-Fi Motion Sensor
• Say Goodbye to EHR Fatigue
• Connecticut Fights AI in Health Insurance

plus: 8 funded Startup this week

#AI #AIhealthcare #AInews

www.aiinlabcoat.com/p/ai-spots-d...

A.I. should be trained to reason like a team of multidisciplinary physicians, well suited for complex cases
@nature.com commentary
www.nature.com/articles/d41...

That's right

Reimagining FAIR for an AI World: Frontiers introduces FAIR² Data Management On Open Data Day 2025, Frontiers is launching the FAIR² (FAIR Squared™) Data Management Pilot, a first-of-its-kind peer-reviewed service that helps researchers

www.frontiersin.org/news/2025/03... Reimagining FAIR for an AI World: Frontiers introduces FAIR² Data Management
AI-Powered Curation Turns Research Data into a Catalyst for Breakthroughs

Hinton vs Musk Standing with my long-term nemesis, standing with science

Standing with Hinton, standing with science.

Please @standupforscience.bsky.social March 7, links enclosed.

open.substack.com/pub/garymarc...

AI Tracks Brain Aging in Real-Time plus: Oregon Bans AI Nurse Titles

This week's AI Healthcare Roundup:
• AI Tracks Brain Aging in Real-Time
• Oregon Bans AI Nurse Titles
• AI in Insurance Hurts Patient Care

plus: 15 funded Startup this week

#AI #AInews #AIinHealthcare
www.aiinlabcoat.com/p/ai-tracks-...

Why is Mars red? Scientists may finally have the answer A new study shows a water-rich mineral could explain the planet's color -- and hint at its wetter, more habitable past.

Turns out Mars’ red color comes from ferrihydrite, a mineral that forms in wet environments. So the planet wasn’t always dry—it had a past, a history.

Now it just sits there, covered in dust, reminding us that things change and not always for the better.

www.sciencedaily.com/releases/202...

1,000 artists release 'silent' album to protest UK copyright sell-out to AI | TechCrunch The U.K. government is pushing forward with plans to attract more AI companies to the region by changing copyright law. The proposed changes would allow

I get the protest, but the fact that artists even have to do this to be heard says everything.

AI training without permission is just another way of saying "free labor." If musicians (or any creator) have to "opt out," they’re already losing.

techcrunch.com/2025/02/24/1...

we have AI writing essays, cars driving themselves, and yet a self-checkout still panics when I try to buy produce.

AI Boosts Atrial Fibrillation Care plus: UnitedHealth AI Lawsuit Moves Forward

This week's AI Healthcare Roundup:

• AI Boosts Atrial Fibrillation Care
• Affordable AI MRI for Early Detection
• UnitedHealth AI Lawsuit Moves Forward

plus: 19 funded Startup this week

www.aiinlabcoat.com/p/ai-boosts-...

Accelerating scientific breakthroughs with an AI co-scientist

Google’s new AI co-scientist can propose hypotheses, and suggest experiments. Maybe write your papers too.

I can't wait for reviewers to reject them with the some vague feedback and demand 10 more unnecessary citations.

research.google/blog/acceler...

Exclusive: These universities have the most retracted scientific articles A first-of-its-kind analysis by Nature reveals which institutions are retraction hotspots.

A first-of-its-kind analysis reveals which universities have the highest rates of retracted scientific papers. Some institutions have retraction rates 50 times the global average!

www.nature.com/articles/d41...

I would love for that to be the case. We're set up for it, with many top research-intensive institutions and the talent with it. The issue with Canada is its risk-averse funding mentality. It's always the safe bet; we face this all the time. Agencies fund big names and near-proven ideas.

reviewer #1: "great work, minor edits."
reviewer #2: "I think the entire field of study should be reconsidered."

my hydro bills have that fun element of surprise, like a mystery box, but instead of a cool prize, it’s just financial stress.