Chantelle Sephton's Avatar

Chantelle Sephton

@chantellesephton.bsky.social

I am a Full Professor at Université Laval and our research focuses on understanding the complex mechanisms driving amyotrophic lateral sclerosis (ALS) and Frontotemporal dementia (FTD). For more info: https://www.sephtonlab.ca

46 Followers  |  64 Following  |  4 Posts  |  Joined: 06.02.2025  |  1.4039

Latest posts by chantellesephton.bsky.social on Bluesky


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Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity ALS leads to loss of motor neurons, muscle atrophy and systemic energy imbalance. Marcadet and Pelaez et al. report lipid droplet accumulation and peroxida

The final version of our article is now online in the February issue of Brain! 🥳:

Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity url: academic.oup.com/brain/articl...

09.02.2026 22:00 — 👍 0    🔁 0    💬 0    📌 0
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A subcellular map of translational machinery composition and regulation at the single-molecule level Millions of ribosomes are packed within mammalian cells, yet we lack tools to visualize them in toto and characterize their subcellular composition. In this study, we present ribosome expansion micros...

🤯 www.science.org/doi/10.1126/...

30.10.2025 13:33 — 👍 0    🔁 0    💬 0    📌 0
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Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity ALS leads to loss of motor neurons, muscle atrophy and systemic energy imbalance. Marcadet and Pelaez et al. report lipid droplet accumulation and peroxida

I am delighted to share our new publication! Huge thanks to my team and all of our outstanding co-authors for their contributions to this work: Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity: academic.oup.com/brain/articl...

24.09.2025 14:32 — 👍 1    🔁 1    💬 0    📌 0
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NIH funding delivers exponential economic returns — Harvard Gazette Report finds all 50 states reap gains in patient health, job creation, research resources, business development.

In fiscal year 2024, the report found, NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide.

news.harvard.edu/gazette/stor...

12.03.2025 23:49 — 👍 4106    🔁 1495    💬 87    📌 82
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ANALYSIS | The U.S. has covertly destabilized nations. With Canada, it's being done in public | CBC News Former senior Canadian intelligence officials say Canada needs to be on the lookout for campaigns aimed at destabilizing the country amid U.S. President Donald Trump's escalating 51st state threats. T...

Not an article I ever expected to read...How the US is destabilizing Canada.
www.cbc.ca/news/politic...

12.03.2025 20:36 — 👍 1    🔁 1    💬 0    📌 0
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Congratulations to Dr. Mari Pelaez for earning her PhD in Neuroscience at Université Laval, Canada! Check out some her published work on ALS: www.sephtonlab.ca/publications

13.02.2025 22:44 — 👍 4    🔁 0    💬 0    📌 0

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