Vlad Bondarenko

Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Boundary constraints can determine pattern emergence The robust patterning of cell fates during embryonic development requires precise coordination of signalling gradients within defined spatial constraints. Using a geometrically confined in vitro syste...

New work with Saunders & Charras labs

Physical boundaries guide cell fate decisions during human trunk development

Reaction Diffusion model shows how geometry shapes biology with TBXT expression forming consistent domains regardless of colony size & shape

www.biorxiv.org/content/10.1...

Can robots in a swarm act like the cells of an organism? Thanks to Sedeer El-Showk for the new article in @nature.com, which highlights the work of a number of research groups, including our own, on how “Robots demonstrate principles of collective intelligence”. www.nature.com/articles/d41...

🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social

🔬 The next international Developmental Biology course, organized by Institut Curie with @sorbonne-universite.fr, will focus on "From stem #cells to #morphogenesis".

📅 Apply by:
• July 20 (3.5 weeks with hands-on workshop)
• Aug 31 (10 days of seminars)

🔗 training.institut-curie.org/courses/deve...

It’s always a bit awkward to write about personal experiences. I tried to touch on what Pride means to me and ended up reflecting on heteronormativity, passing, and allyship. Thank you @slefkopoulos.bsky.social for the great opportunity! @ucph.bsky.social
#LGBTQIA+ #PRIDE #Diversity

Please pread the word.

We have just launched the Hubrecht International PhD Program (HIPP).

Are you looking for a PhD position in molecular and developmental biology or related subject in an international, very supportive and collaborative environment?

Then apply to the HIPP!! 👇

Oh, what a great fun it was! Thank you @embldbunit.bsky.social, Karen Alim, @jamesbriscoe.bsky.social , @nicolettapetridou.bsky.social , @jordivangestel.bsky.social , @hanhtkvu.bsky.social , @aikmi.bsky.social, and all instructors and participants. Back to the lab now - inspired & motivated!

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...

It has been an amazing collaboration between the Turco Lab and Computational Biology at @fmiscience.bsky.social - Thank you !

Super excited to share our new selection-free CRISPR-Cas9 editing protocol for Dictyostelids, generating 80% KO and 30% KI efficiencies without selection in D. discoideum, and being effective in Dictyostelid species that diverged millions of years ago! www.biorxiv.org/content/10.1...

preprint alert: www.biorxiv.org/content/10.1...

The DB Unit Summer School, "Transitions in Developing Systems," kicked off with an incredible talk by Thibaut Brunet @thibautbrunet.bsky.social from the Pasteur Institute @pasteur.fr on the fascinating transition from unicellularity to multicellularity in choanoflagellates #EMBLDevBio

Huge congratulations, Ina & the group, well deserved!! 🥳 👏

We thought we were just studying mesoglea biogenesis…Turns out Nematostella has been hiding a sophisticated backup pressure valve! Work driven by the talented PhD student Soham Basu! @embl.org‬ www.biorxiv.org/content/10.1...

Want to work on data management for cutting edge light-sheet microscopy? The group of Jan Huisken in Göttingen is looking for a PostDoc as part of NFDI4BioImage:
www.uni-goettingen.de/de/644546.ht...
As a plus, you will be able to work with us on image analysis ;)

Join this week's VGZT seminar to explore evo-devo in eels and how rigidity transitions shape embryonic tissue organization! 🐟

Thank you @thomaslecuit.bsky.social for organising! 👏

Please join next week‘s Western 🌙 VGZT:
🗓️ Thursday, May 22
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

@aliseleit.bsky.social
👉Developmental heterochrony & evolution of segmentation in eels

@laura-rustarazo.bsky.social
👉Rigidity transitions & epithelial organization in 🐟 embryos

An integrated transcriptomic cell atlas of human endoderm-derived organoids - Nature Genetics The human endoderm-derived organoid cell atlas (HEOCA) presents an integrative analysis of single-cell transcriptomes across different conditions, sources and protocols. It compares cell types and sta...

Integrated Organoid Atlas benchmarks new protocols, even more impressive as a Highly Variable Cohort for comparison against perturbation and disease models: nature.com/articles/s41... Lead by @quanxu.bsky.social, in collaboration with Lennard Halle and @fabiantheis.bsky.social

Want to help shape a young & dynamic research group while using #organoids to ask how #chromatin dynamics, #cell_state, & the #exposome contribute to #neuroendocrine #cancer? Apply for a postdoc position in our lab @embl.org Barcelona! #cancer_models.
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Want to compress cells? Want to know how to do it, which mechanism could sense compression or wondering why should you compress cells? Checkout our review to know more about that!!

Celebrating 10 years of our lab with a new preprint:
www.biorxiv.org/content/10.1...
How does enhancer location within a TAD control transcriptional bursts from a cognate promoter?
Experiments by Jana Tünnermann and modelling by Gregory Roth

Whoop-whoop!! 🙌
Cool to see your story out, congratulations, Marloes! 💫

Stem cell culture conditions affect in vitro differentiation potential and mouse gastruloid formation Aggregating low numbers of mouse embryonic stem cells (mESCs) and inducing Wnt signalling generates ‘gastruloids’, self-organising complex structures that display an anteroposterior organisation of ce...

Very happy to share that our paper on stem cell culture conditions is now out! doi.org/10.1371/jour... We found that modulating mESC culture conditions influences gastruloid elongation and lineage specification, and helps with making the protocol more reproducible in our hands! more below 🧵⬇️ [1/7]

🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint.bsky.social !

A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌

🧵⤵️

Very excited to share our work on calcium dynamics during early mouse development at #biologists100. Stop by Poster 182 to say hi and learn more!

@biologists.bsky.social @the-node.bsky.social @focalplane.bsky.social @bsdb.bsky.social @srinivas-lab.bsky.social

⭐️ Please Fwd. Are you in Paris on 16th May? See👇 poster of symposium on « Information processing in biological systems » @collegedefrance.bsky.social Fantastic line of speakers 🤩.
It is free, w/o registration, and it will be exciting.m!
Follows from my series of lectures at CdF last fall.

My first post in Bluesky and first invited talk as a new PI. Come see how we use in vivo imaging to understand how spatio-temporal changes in metabolism drive responses to oncogenic mutations in the skin. Thanks so much to the organisers for giving me this platform.

March is #endometriosis awareness month 💜

Many questions remain to be answered, but we look positive on the future 🌟

📰 2,412 research articles were published on endometriosis in 2024, ranging from Clinical management and guidelines to Endometriosis-associated ovarian cancer👍