University of Minnesota Infectious Diseases

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Enhancing the Care of Patients With Bone and Joint Infections Through Educational Interventions Abstract. Musculoskeletal infections represent a significant proportion of the clinical workload for infectious diseases (ID) providers, often presenting c

Musculoskeletal infections make up a major share of the ID clinical workload, yet many clinicians feel underprepared for their complexity.
Faculty member Dr. Tai created an online resource to make high-yield MSK ID knowledge accessible and practical for all learners. #IDSky

Welcome to our fellows.

Celebrating Match Day! 🎉
Welcome to our future colleagues. We can’t wait for you to join the University of Minnesota ID team! #Match2025 #IDSky

The hepatitis B birth dose is safe, effective, and a critical shield against lifelong infection. Delaying it puts infants at risk for preventable, chronic HBV. Universal newborn vaccination saves lives and remains essential public health practice. #HepatitisB #VaccinesWork #IDSky

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New HIV vaccine research shows that escalating dose mRNA priming plus protein VLP boosts produced strong antibody responses in rabbits. Broad neutralization remains difficult and continued innovation is essential. #HIVresearch #UMNproud #IDSky

Genetic Analysis of Metabolic-associated Steatosis Liver Disease in a Colombian Cohort Numerous studies have identified genetic variations linked to the development and progression of Metabolic Associated Steatosis Liver Disease (MASLD), but their relevance is not completely understood ...

New research from Dr. Debes:
In a Colombian cohort with Metabolic Associated Steatotic Liver Disease, the PNPLA3 risk allele was highly prevalent and strongly linked to advanced fibrosis and cirrhosis. Gene combinations also increased risk. #GISky

Highly efficient production of HIV-1AD8 gp120 in mammalian cells | Journal of Virology There are approximately 40.8 million people living with HIV-1 (PLWH) worldwide, with an estimate of about 1.3 million new HIV-1 infections in 2024, highlighting the urgent need for an effective HIV-1 ...

New research from Dr. Alon Herschhorn and team reveals a more efficient way to produce the HIV-1 gp120 protein, a key component for vaccine and viral entry studies. The stable cell line method yields 50× more protein than traditional approaches. #IDSky

NEJM and public health group are launching rival to CDC’s MMWR publication Two institutions are coming together to create an alternative to the CDC’s vaunted Morbidity and Mortality Weekly Report

@nejm.org + @cidrap.bsky.social are launching Public Health Alerts — a new rapid-report platform to rival MMWR. Free, timely, and aimed at practitioners & researchers alike.
#IDSky

Mortality from advanced HIV disease remains high. The NIRVANA trial, led by Dr. Caleb Skipper and colleagues, tests whether treating CMV viraemia with valganciclovir can save lives. A phase 2b study now underway in Uganda and South Africa. #IDSky #Research

2025 ICM: Debridement, Antibiotics, and Implant Retention (DAIR) James Cashman, Paul McCarroll, Peter Choong, Pedro Ivo Carvalho, Nicolaas Budhiparama, Ewout S Veltman, David Dewar, Mehmet Kursat Yilmaz

What’s the optimal antibiotic duration after DAIR for acute periprosthetic joint infection (PJI)?

🌍 An international consensus led by ID faculty Dr. Geno Tai and colleagues recommends at least 12 weeks of therapy. #IDSky #MedSky #OrthoSky

🌍 Diseases cross borders—and ID specialists need global skills to match.

Take our new online course: “Travel and Tropical Medicine for the Infectious Disease Specialist.”

🎓 30 CME credits
🧬 Prep for CTropMed®
📚 Interactive, case-based, flexible learning

#IDSky #MedSky

New research from Dr. Susan Kline and colleagues shows that antibody levels after the Novavax (NVX-CoV2373) vaccine strongly predict protection against severe COVID-19. Higher neutralizing antibodies meant far fewer severe Delta infections.
#IDSky
academic.oup.com/cid/advance-...

We’re heading to #IDWeek2025!

Along with our colleagues at the Minnesota Department of Health and across the Twin Cities, we will be sharing:

📰 26 posters
🎤 12 symposiums
🗣️ 4 oral abstracts
🏆 1 plenary

We’re excited to showcase the incredible work coming out of Minnesota. See you there! #IDSky

Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care Among Ugandan outpatients with advanced HIV, elevated serum CRP (≥10 mg/L) predicted 30-day risk of opportunistic infection, hospitalization, and death. Ea

High CRP = high risk.
In a Ugandan cohort of 1,378 people with advanced HIV (CD4 ≤200), Dr. Boulware’s team found that CRP ≥10 mg/L predicted a 4× higher risk of hospitalization and 10× higher risk of death within 30 days. #IDSky

Topics include
🌡️ Climate change & health
🦟 Vectorborne diseases
🐦 H5N1 spread
💊 Long-acting PrEP & doxy-PEP
🧬 Genomic tech & public health
🌍 Travel & “hot topics”

Join us in Minneapolis to connect, learn, and collaborate. #Medsky

🦠 Save the date!
Emerging Infections 2025
📍 Minneapolis, MN | 🗓️ Nov 21, 2025

Now in its 31st year, this conference cohosted by Mayo Clinic, the University of Minnesota, and MDH unites clinicians, laboratorians, and public health experts to tackle today’s emerging infectious threats. #IDSky

Home - Doctor Fungus Welcome to Doctor Fungus! An Educational Website of theMycoses Study Group Education and Research Consortium (MSGERC)   [View Legal Information] Where to Start Mycology Case of the Month An Introducti...

There’s now an app for all things fungi 🦠🍄
Dr. Matthew Pullen, Assistant Professor at the University of Minnesota, helped launch Dr Fungus—a free app that brings the trusted resource to your phone.

Explore fungal infections, antifungal treatments, and case-based learning—all in one place.

Can liposomal amphotericin B be used as a preventive measure for cryptococcal meningitis? Published in Expert Review of Anti-infective Therapy (Just accepted, 2025)

Dr. Radha Rajasingham & Dr. Nathan Bahr explore this critical question in a new article. Their work highlights ongoing knowledge gaps around ART timing, antifungal regimens, and how to ensure treatments are effective, safe, and accessible worldwide. 🌍💊
www.tandfonline.com/doi/full/10....

Cerebrospinal Fluid Mononuclear Cell Phenotype and Activation Predictors of 2-week and 1-year survival among Persons with HIV-Associated Cryptococcal Meningitis AbstractBackground. Despite efforts to optimize therapy for HIV-associated cryptococcal meningitis (CM), survival outcomes remain poor. It is unclear how t

Dr. David Boulware’s latest study sheds light on the immune response in HIV-associated cryptococcal meningitis.

🧪 Early deaths were linked to immune exhaustion in cerebrospinal fluid cells. Low CD8+ T cells + higher PD-1 expression = higher risk. #IDSky

A clinical practice guideline for tuberculous meningitis Tuberculous meningitis is the most severe form of tuberculosis, causing death or disability in around half of those affected. There are no up-to-date international guidelines defining its optimal mana...

🧠💉 Exciting news! Our faculty member Dr. Nathan Bahr co-authored the brand-new Clinical Practice Guideline for Tuberculous Meningitis. This work provides crucial recommendations for diagnosis & treatment of this devastating infection worldwide. #IDSky

Cryptococcosis remains a leading cause of death in people with HIV. Dr. David Boulware’s FLOOR trial tested whether lower flucytosine dosing could keep treatment effective while reducing side effects. #IDSky

📅 Save the date: Sept 7–9, 2025
📍 Minneapolis, MN

Join us for the 2025 Congenital CMV Public Health & Policy Conference!

We’ll cover diagnosis, treatment, prevention, and family support. Our goal? Fewer babies born with CMV—and better lives for those affected.

#CMV #PublicHealth #IDSky

The Halifax Declaration, born from this historic gathering, is a call to action against rising global inequities and restrictive migration policies. Co-created with those who’ve experienced displacement, it builds on decades of human rights work. #RefugeeHealth #IRMHC2025

The Halifax Declaration: protecting health, dignity, and human rights in an era of forced displacement

Faculty Dr. William M. Stauffer co-led the 2025 International Refugee and Migration Health Conference in Halifax—bringing together 600+ global leaders to address health equity for displaced people. 🧵#IDSky

And shoutout to Dr. Elizabeth B. Hirsch @ebhirsch.bsky.social from the UMN College of Pharmacy—also part of the expert panel behind the new IDSA national UTI guidelines. 👏📚

Teamwork across UMN helping shape evidence-based care!
#UMNproud #Pharmacy #UTI #AntibioticStewardship #IDSky

🚨 New National Guidelines Alert!
Our very own Dr. Dimitri Drekonja together with colleagues just authored the IDSA guidelines for urinary tract infections.

ID expertise from the University of Minnesota helping shape clinical care nationwide. 💪💊 #IDSky #UMNproud #UTI #MedSky #InfectiousDiseases

✨ #FollowFriday ✨
We’re so close to 4,000 followers! Help us get there by tapping that follow button and tagging a colleague who should be part of our community. 🧫🌍🧠

Grateful for all of you who make this space smarter, kinder, and more curious. #IDSky #MedSky

Prognostic Value of C-Reactive Protein in Adults With Tuberculous Meningitis: A Prospective Cohort Study Among a cohort of adults with tuberculous meningitis, including 83% living with human immunodeficiency virus, we found that baseline C-reactive protein ≥40

🧠📈 New research from @drboulware.bsky.social @natebahrid.bsky.social
In people with TB meningitis (a serious brain infection), high levels of inflammation in the blood were linked to worse recovery.

A simple blood test (CRP) could help doctors predict who’s at higher risk early on. #IDSky

Turns out, these quiet immune cells are essential bodyguards, protecting the brain even long after the infection is gone.