Dr. David Boulware, MD MPH

As @gregggonsalves.bsky.social said, here is the main winner in the forced departure of Carl Dieffenbach.

New "Osterholm Update" podcast episode! @mtosterholm & @cvdall review the latest flu trends and how this year's vaccine compares to circulating strains. Dr. O also discusses H5N1 impact on mammals in Antarctica and answers an ID Query on infant botulism

www.cidrap.umn.edu/a...

Why are CLSI breakpoints for Candida so low? 8 mcg/mL is considered "resistant" in Candida yet this is the MIC50 for Cryptococcus species where we just use higher dose fluconazole 800-1200mg/day.

Is the problem that the FDA package insert says the Candida dose is 100 mg or 200mg once daily?

#idboardreview A Pt w/travel to Mexico a few months prior (drank tap water, ate raw vegetables) noticed a small worm-like object on inner surface of her lower lip. She removed the object with a needle. Dx? #medEd #idmeded #IDsky #parasitology

Is a 28 Point Munich Agrement the solution?
Peace in Our Time.

Webinar: Attributes of pathogen genomic data platforms supporting timely and equitable sharing - Pathogen Forum This is part of a series organized by WHO/IPSN in collaboration with the Pathogen Genomics Funders Forum.

Webinar: Attributes of pathogen genomic data platforms supporting timely and equitable sharing - Pathogen Forum.
24-Nov-2025, 1 pm CET / 7am EST
pathogenforum.org/webinar-attr...

Great northern lights night in Minnesota

I would vote for vaccine over natural infection.

There are definitely some other issues

While normally I would contact the author to request they correct out of courtesy… my experience has been poor at authors then actually taking action to correct errors. Scientific literature is polluted with articles which are incorrect.

Should one be flattered when a published manuscript that is clearly AI written hallucinates and creates citations by you that you never wrote? Paper is not very good, omitting from the abstract use of a bad CrAg test which has poor performance.

What should one do? Contact editor? Or author?

Career Opportunity! The California Department of Public Health, TB Control Branch is recruiting for an epidemiologist position.

Interested persons may apply via this website: sjobs.brassring.com/TGnewUI/Sear...

#Tuberculosis #TBSKy

‎Dr. Fungus ‎The Dr. Fungus app serves as a companion to the official Dr. Fungus website, the Mycoses Study Group Education and Research Consortium resource for fungal disease education. This app provides up-to-d...

Is there a fungus amongst us?
Dr. Fungus App for medical mycology on your phone.

Apple iOS Store: apps.apple.com/us/app/dr-fu...
Google Play Store: play.google.com/store/apps/d...

Insurance via ACA marketplace is projected to rise by 21% in Minnesota in 2026.

No longer... CDC EIS RIF'ed.

Vaccine for typhoid, invasive Salmonella shows promise in phase 1 trial

Researchers say the investigational three-strain vaccine produced a strong immune response and was well-tolerated in its first human trial.

www.cidrap.umn.edu/s...

Equal partnership -- and being open to new collaborations bringing new expertise and enthusiasm to tackle complex problems in the realm of HIV and opportunistic infections.

Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care Among Ugandan outpatients with advanced HIV, elevated serum CRP (≥10 mg/L) predicted 30-day risk of opportunistic infection, hospitalization, and death. Ea

Predictive value of C-reactive protein for hospitalization and mortality among people with advanced HIV disease in Uganda receiving the WHO-recommended package of care

Nice paper by U of MN MD/PhD student Eli Schwartz on behalf of the ENCORE Team.
track.smtpsendmail.com/9032119/c?p=...

Twin Cities Marathon Day.

Brunch with neighbors on front lawn cheering on runners.

Excited to speak at UT Houston-Methodist on Friday on "Innovative Clinical Trial Designs in ID"

First time I have been back to Houston in 26 years. It's still hot... and even more buildings on medical campus.

The new Dr. Fungus app is now available on all iOS and Android devices. This app serves as a handy companion to the Dr. Fungus website, providing quick, easy access to information on fungal organisms, medical mycoses, and antifungal medications. We will be continuing to improve and refine the app.

‎Dr. Fungus ‎The Dr. Fungus app serves as a companion to the official Dr. Fungus website, the Mycoses Study Group Education and Research Consortium resource for fungal disease education. This app provides up-to-d...

Mycosis Study Group has released DrFungus app for phones as a reference companion for yeast and mold infections.

iPhone apps.apple.com/us/app/dr-fu...
Android play.google.com/store/apps/d...

App designed by Dr Matt Pullen. @msgerc.bsky.social

More Than 20 Medical Groups Call For RFK Jr. To Resign
#IDSky #MedSky

www.idsociety.org/news--public...

Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospective Cohort Study Early metformin treatment in overweight or obese adults with recent coronavirus disease 2019 infection significantly reduces the risk of developing post–co

Two studies, same signal👇
📊 COVID-OUT RCT: 41% ↓ long COVID with 14d metformin (1500 mg/day by Day 6).
📊 CID UK cohort (766k pts): 64% ↓ long COVID if metformin started within 90d.

Cheap, safe, generic drug. Replication across RCT + real world = 🔥

#MedSky

Are childhood vaccination requirement to attend public school (with a parental opt out) equivalent to slavery? No.

IDSA @idsainfo.bsky.social calls for the resignation of RFK Jr. as "Health" Secretary.
Are there other organizations which will call for this?

www.idsociety.org/news--public...

Much more interesting and relevant would be the EPIC-SR results which showed no such benefits.

That would be more relevant data for today’s population in 2025 and beyond. @ofidjournal.bsky.social

Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospective Cohort Study Early metformin treatment in overweight or obese adults with recent coronavirus disease 2019 infection significantly reduces the risk of developing post–co

#Metformin reduces risk on developing #PCC from 27,9% to 11.2% if started within 90 days of #SARS-COV-2 infection in #overweight/#obese patients in real-world settings (624 308 patients propensity-score)

Risk Difference At 1 y (%) -12,58%
Adjusted Hazard Ratio 0.36 academic.oup.com/cid/advance-...

Patient-Reported Outcomes of Nirmatrelvir Treatment for High-Risk, Nonhospitalized Adults With Symptomatic COVID-19 In a phase 2/3 trial, high-risk adults with confirmed symptomatic COVID-19 receiving nirmatrelvir/ritonavir twice daily for 5 days reported global impressi

Why is OFID publishing a #covid study from 2021 reporting #paxlovid secondary trial results by Pfizer in high risk unvaccinated results - while burying the same results in the lower risk trial. @ofidjournal.bsky.social

Low risk results were presented at IDweek

academic.oup.com/ofid/article...

Opinion | America First? Not When It Comes to Your Health.

America First? Not When It Comes to Your Health. www.nytimes.com/2025/08/24/o...

Money saved by impoundment. Opportunities lost. Video explains such opportunities to advance medical research to improve Anetjcan’s health