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Megan Dennis

@mydennis.bsky.social

Assoc Prof & Assoc Director of Genomics @UCDavis Genome Center. Neurogenetics, evolution/function of gene duplications, human, zebrafish. Posts my own. #firstgen #jogger (mee-gun) http://dennislab.org

2,534 Followers  |  1,785 Following  |  280 Posts  |  Joined: 20.10.2023
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Posts by Megan Dennis (@mydennis.bsky.social)

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GENETICS: @mydennis.bsky.social from University of California Davis discussed the querying complex genomic regions important in human disease and evolution at the 2026 AGBT General Meeting. #AGBTGM26

25.02.2026 02:29 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Long-Read Sequencing Workshop The program will involve sessions on Genome Evolution, Genome Regulation, Transcriptomics, Rare Diseases, Common Diseases, and Viral and Microbial Genomes. Committed speakers include Adam Phillipy (NH...

JAX Long-Read Sequencing Workshop

Keynotes by @aphillippy.bsky.social & @mydennis.bsky.social

Co-organized by @olgaanczukow.bsky.social, @christinebeck.bsky.social & Mark Adams

✈️ Trainee travel awards
πŸ“ Abstracts due March 3
πŸ₯Ό Optional wet-lab training session
πŸ”— www.jax.org/education-an...

11.02.2026 12:52 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1

Thank you, Crystal!

29.01.2026 01:41 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 2
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2 First-Gen Scientists on Curiosity, Community and Discovery Megan Dennis, associate professor in Biochemistry and Molecular Medicine, and Siobhan Brady, professor in the Department of Plant Biology and the Genome Center, are more than an just office neighbors ...

Please check out these amazing women! They are fantastic scientists, committed mentors, supportive friends and honestly super stars! 🀩@bradylabs.bsky.social @mydennis.bsky.social @ucdavis.bsky.social
www.ucdavis.edu/news/podcast...

28.01.2026 00:25 β€” πŸ‘ 34    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0

Thank you!

24.01.2026 02:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Anyone in the U.S. got an ERK biosensor zebrafish line they'd be willing to share/ship to VA? vascular specific would be preferred, but I'll take global too. @zebrafishrock.bsky.social

22.01.2026 15:56 β€” πŸ‘ 3    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1

Thank you all!

21.01.2026 16:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Recently learned that I will be promoted to FULL PROFESSOR(!) this coming summer. So happy and thankful for those that have supported me along the way, including collaborators, mentors, colleagues, friends, family, trainees, and letter writers. #bighugs #youdabest #firstgen

21.01.2026 10:26 β€” πŸ‘ 85    πŸ” 3    πŸ’¬ 16    πŸ“Œ 2
10-day weather forecast in Davis, CA showing warmer and arguably more livable winter conditions than much of the rest of the US, providing yet another reason to apply to a faculty position at UC Davis

10-day weather forecast in Davis, CA showing warmer and arguably more livable winter conditions than much of the rest of the US, providing yet another reason to apply to a faculty position at UC Davis

While we are still recovering from an atmospheric river, I can’t complain too much about this Davis winter weather πŸ‘€

22.12.2025 23:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Please repost and share widely - winter break is a perfect time to assemble application materials πŸ˜…

22.12.2025 23:24 β€” πŸ‘ 4    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
Phylogenetic tree showing relationships between zebrafish, mice and cartilaginous fishes. It shows the 3R genome duplication event in teleost lineage. Credit to MacDonald et al. 2018.

Phylogenetic tree showing relationships between zebrafish, mice and cartilaginous fishes. It shows the 3R genome duplication event in teleost lineage. Credit to MacDonald et al. 2018.

Did you know the last common ancestor of #zebrafish and humans was ~450 million years ago? A whole genome duplication event (3R) occurred early in the teleost fish phylogeny. Despite this event, zebrafish and humans have about the same number of chromosomes. #ZebrafishFunFacts πŸ§ͺ

17.12.2025 16:25 β€” πŸ‘ 18    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Absolutely thrilled to share the latest work from my lab focused on the variation and evolution of human centromeres among global populations! We assembled 2,110 human centromeres, identifying 226 new major haplotypes and 1,870 Ξ±-satellite HOR variants. www.biorxiv.org/content/10.6...

16.12.2025 16:05 β€” πŸ‘ 108    πŸ” 46    πŸ’¬ 4    πŸ“Œ 2
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CiFi: accurate long-read chromosome conformation capture with low-input requirements. #HiFi #LongRead #Sequencing @natcomms.nature.com πŸ§ͺ🧬 πŸ–₯️
www.nature.com/articles/s41...

16.12.2025 11:30 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Robert E. Chason Endowed Chair in Translational Research, MIND Institute University of California, Davis is hiring. Apply now!

Consider applying for the Robert E. Chason Endowed Chair in Translational Research at the UC Davis MIND Institute!

Join a vibrant community of colleagues studying neurodevelopment conditions like autism. UC Davis is an excellent place to work and live.

Find more details here: lnkd.in/gZRyViNa

16.12.2025 05:34 β€” πŸ‘ 3    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1

This is a self-self comparison of sequence with repetitive elements annotated?

09.12.2025 22:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thanks also to @mabuelanin.bsky.social in the lab for streamlining aspects of the analysis pipeline πŸ’»

08.12.2025 19:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thank you to everyone working on this study co-led by grad student Sean McGinty and Gulhan Kaya, as well as Jonas Korlach @pacbio.bsky.social. Also, awesome collaborators at USDA (Scott Geib & Sheina Sim) and @sangerinstitute.bsky.social (@marakat.bsky.social, @amakunin.bsky.social, and Mike Quail).

08.12.2025 18:06 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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We also show drastic improvements in identifying chromatin interactions across SDs, highlighting disease-associated human 1q21.1 locus associated with ASD, ID, and include the TAR-syndrome deletion. Our CiFi results suggest that the TAR region represents a TAD "boundary" not observed in Hi-C data.

08.12.2025 18:06 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Thanks to reviewer feedback, we expanded our analysis to show that CiFi multi-contact reads, representing cis chromosomal interactions, increase our ability infer phase from ~10% for Hi-C to >80% for CiFi.

08.12.2025 18:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...

08.12.2025 17:55 β€” πŸ‘ 51    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1

We missed you! Feel better soon πŸ’

06.12.2025 07:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Ice skating

Ice skating

Party

Party

Lab ice skating and winter party ❄️⛄️

06.12.2025 07:44 β€” πŸ‘ 14    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Sideways walrus

05.12.2025 04:14 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Two MMG rising academic stars, Diedre Reitz and Yuka Kitamura Congratulations to Diedre Reitz and Yuka Kitamura, postdoctoral fellows in the Heyer and Namekawa laboratories, respectively, for being awarded prestigious K99 grants from the National Institutes of H...

Very happy to share that I’ve been awarded a K99 Career Development Award from NIGMS for my work on MSH2-MSH6 and its role in recombination-mediated rearrangements.

Big thanks to my mentor, Wolf Heyer, co-mentor, Megan Dennis, letter writers, and colleagues.

mmg.ucdavis.edu/news/two-mmg...

30.07.2025 22:35 β€” πŸ‘ 18    πŸ” 1    πŸ’¬ 3    πŸ“Œ 0
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Long-Read Sequencing Workshop The program will involve sessions on Genome Evolution, Genome Regulation, Transcriptomics, Rare Diseases, Common Diseases, and Viral and Microbial Genomes. Committed speakers include Adam Phillipy (NH...

Join us at this exciting Workshop on #LongReads with keynotes from @aphillippy.bsky.social @mydennis.bsky.social
co-organized by @christinebeck.bsky.social and Mark Adams @jacksonlab.bsky.social Register www.jax.org/longread
#RNA #genomics #bioinformatics #cancer #medicine #evolution #neuroscience

14.11.2025 19:56 β€” πŸ‘ 26    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
Dennis lab lego costume

Dennis lab lego costume

Fishman pumpkin

Fishman pumpkin

Lego Legends of the Genome Center

24.10.2025 18:06 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

The lab is coming out strong with their "fishman" pumpkin-contest submission this year for the Halloween Symposium today @ucdgenomecenter.bsky.social !

Pumpkin credit: @nicholashaghani.bsky.social πŸ‘»πŸŽƒ

24.10.2025 18:03 β€” πŸ‘ 24    πŸ” 1    πŸ’¬ 3    πŸ“Œ 1

Ooh sorry about that @ocklenburg.bsky.social - thx to all authors!

17.10.2025 18:04 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

πŸ˜†

17.10.2025 16:47 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Excellent review from @silparacchini.bsky.social’s lab with a nice bluetorial

16.10.2025 21:59 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0