Eugene Valkov

Stunning footage from earlier today, when the new Kilauea eruption covered the USGS Webcam 3, which is situated in the Halemaʻumaʻu crater near the southern rim of the much larger Kilauea caldera.

This *isn't* what the people of Pompeii saw.

But it's not very far off.

“So long as men can breathe or eyes can see,
So long lives this, and this gives life to thee.”

Movie you've watched more than six time with a gif. Hard mode: no Stars (either War or Trek), LOTR, or Marvel.

GTPBP1 is a GTPase implicated in neurodevelopment. Our cryo-EM maps show GTPBP1 delivering tRNA to ribosome.

Due to delayed GTPase dissociation, mRNA decoding is more stringent than with bona fide delivery factor eEF1A.

Congrats to Denis Susorov and collab with Pestova lab! tinyurl.com/3smdvt3v

We mapped the whole human fallopian tube in 3D and at single-cell resolution via our CODA workflow.

More about this work here: biorxiv.org/content/10.1...

Is it too much to ask that Outlook should stop autocorrecting “oligos” to “olives”?

A graphic explaining how mRNA vaccines work, which was showed to study participants.

Teaching people how mRNA vaccines actually work protects against misconceptions about mRNA vaccination changing the recipient's DNA, without the need to repeat the false claims, according to experiments with over 3,500 participants. In PNAS: https://ow.ly/sVwH50Xzutc

Who would have thought? 🤨

We as a family must have visited every state park in the 200-mile radius

👇🏻 that’s literary talent

And finally: pecan pie, chocolate peanut butter cheesecake, and cranberry curd cake

A spiced and superjuicy turkey with butter and maple syrup glaze per @nigella.bsky.social

Totally agree

Hot apple cider 😋

It’s being made clear to me I’m not permitted to work today #thanksgiving

#RNAsky #RNAbiology

#RNAsky #RNAbiology

😱😱😱

Next generation of 1001 Genomes Plus browser and data download Please indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes

We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.

Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...

Finally out in @nature.com! We uncovered a mechanistic framework for a general and conserved mRNA nuclear export pathway. www.nature.com/articles/s41.... 1/

The bioRxiv and medRxiv sites are currently inaccessible because of an issue with the Cloudflare cybersecurity service. This is affecting many sites but we’re told it’s being resolved.

Skyline of Madison, WI

🚨I am looking for a POSTDOC, LAB MANAGER/TECH and GRAD STUDENTS to join my new lab in beautiful Madison, WI.
We study how our brains perceive and represent the physical world around us using behavioral, computational, and neuroimaging methods.
paulunlab.psych.wisc.edu
#VisionScience #NeuroSkyence

This is Fendi. He is seen here demonstrating the internationally acknowledged sign language for politely requesting uppies. 13/10 would pick him up immediately (TT: isthat_jojo)

We are seeking postdoctoral researchers to study viral RNA and macromolecular complexes using X-ray crystallography, cryo-EM, and biochemical methods.

Structural biology experience is required. Interested candidates should send a CV, a brief research statement, and 2–3 references to kaychoi@iu.edu.

MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.

Or from a single dish of HEK cell culture in the case of two membrane proteins.

Out in Nature Methods now! lnkd.in/gpyBSceg

Wonderful collaboration with the Efremov lab.

Multiple tenure-track faculty positions at the UNC Lineberger Comprehensive Cancer Center in Chapel Hill!
We seek creative scientists working in fundamental molecular, cellular, and computational areas. Basic and translational cancer research, all ranks.
unc.peopleadmin.com/postings/309...

RESEARCH PAPER: A kinetic ruler controls mRNA poly(A) tail length
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full

#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC

A #VeteransDay walk along the Monocacy Battlefield, Frederick, Maryland.

RNA stability enhancers for durable base-modified mRNA therapeutics - Nature Biotechnology A systematic screen identifies RNA elements that enhance the stability and translation of base-modified mRNA.

Tremendous paper from Narry Kim’s lab identifying a sequence element that recruits cellular factors to exogenous mRNAs to ‘rejuvenate’ their poly(A) tails leading to a huge boost in output. Significant implications for therapeutics. Now, I wonder what the factor X is…

www.nature.com/articles/s41...

Establishing benchmarks for quantitative mapping of m6A by Nanopore Direct RNA Sequencing. #DirectRNAseq #Sequencing #RNAmodifications @nanoporetech.com
www.biorxiv.org/content/10.1...