Hope this will be useful! Thanks to Marion Dutkiewicz and Jozsef Soki! @upcite.bsky.social @inserm.fr @iame-umr1137.bsky.social

Beta-lactamases in anaerobic, intestinal bacteria: a narrative review Anaerobic bacteria in the human intestinal microbiota play a pivotal role in antibiotic resistance, primarily through the production of β-lactamases. …

Antibiotic resistant genes from pathogenic bacteria are very well known, but what about those carried by commensals from our intestinal microbiota? we wrote a short narrative review on this topic, focusing on beta-lactamases (open access). www.sciencedirect.com/science/arti...

This week at #IccMg in Geneva 🇨🇭

Nicola Segata will discuss the concepts of personalized nutrition that build on or integrate microbiome!

Full program here: clinicalmetagenomics.org?page_id=286

📅 Deadline to submit your abstract: 17 September 2025

👉 Discover the full program and submit your abstract here:
clinicalmetagenomics.org

We look forward to your contributions and to an inspiring exchange of ideas!

🚨 NEW OPPORTUNITY FOR YOUNG SCIENTISTS! 🚨

We’re excited to announce the “5 BEST ABSTRACTS” initiative at the upcoming ICCMg10!

✅ CALL FOR ABSTRACTS
The 5 best abstracts will have their registration fees waived!
(Eligibility: posters submitted by young scientists under the age of 35)

you're right they are D-Ala D-Ala ligases, selected on cycloserine and not on glycopeptides, my bad

though from functional metagenomics experiments single genes seem to confer a lower susceptibility to glycopeptides when transferred/expressed in E. coli

I loved this one, but an update may be necessary (especially with regards to detection) Review Nat Rev Microbiol . 2015 Feb;13(2):116-23. doi: 10.1038/nrmicro3399. Epub 2014 Dec 15.
What is a resistance gene? Ranking risk in resistomes
José L Martínez, Teresa M Coque, Fernando Baquero

I have been grumpy on many occasions :-) I would say that the main issues are (1) the inadequation between the choice of the database and the scientific question (e.g. choose ResFinder to look for intrinsinc ARG of soil bacteria) and (2) the lack of discussion/criticism of the results

When ➡️ November 6-7 2025
Where ➡️ Campus Biotech Geneva, Switzerland
How to register ➡️https://clinicalmetagenomics.org/?page_id=53
Abstracts are welcome ➡️https://clinicalmetagenomics.org/?page_id=265

Looking forward to seing you in Geneva to celebrate the 10 years of clinical metagenomics!

For this 10th birthday, we will review the last decade of clinical metagenomics and forecast the next. To this aim, we have built a line-up of top speakers, with Charles Chiu, Ruth Ley, Nicola Segata, Curtis Huttenhower, Flaminia Olearo, Alice Chen-Liaw, Iwijn De Vlaminck, David Gaston and others!

The program of the 10th International Conference on Clinical Metagenomics is (ICCMg10) is online!
clinicalmetagenomics.org?page_id=286

NGS Platforms, Pitfalls, and Progress Experts Etienne Ruppe and Stefan Green reflect on the evolving role of next-generation sequencing

After our session at the last @escmid.bsky.social meeting, Stefan Green and I were interviewed by Jessica Allerton for The Pathologist Magazine about NGS and its applications in infectious diseases. Bravo Jessica and thank you for the opportunity! thepathologist.com/issues/2025/...

Environmental reservoir of resistance genes for the last resort antibiotic Cefiderocol. https://www.biorxiv.org/content/10.1101/2025.05.26.656069v1

Congrats @remigsc.bsky.social this is the culmination of a colossal work!

9th International Conference on Clinical Metagenomics (ICCMg9): meeting report The 9th International Conference on Clinical Metagenomics (ICCMg9) continued its tradition of advancing the clinical applications of metagenomics. Experts from around the world shared insights on path...

The 9th International Conference on Clinical Metagenomics (ICCMg9) meeting report is out in Trends in Microbiology www.cell.com/trends/micro...
See you in Geneva for the ICCMg10! www.clinicalmetagenomics.org

Congrats @svetlanaup.bsky.social for this brilliant and useful piece of work!

Full paper and all supp mat doi.org/10.1016/j.ij...

For clinical metagenomics, we also show that distinguishing contaminants from actual pathogens can be improved using data such as 16S qPCR Ct value, number of CMg species identified, number of non-human CMg reads and, highest genome completeness among CMg species.

Glad to share our work about the comparison between clinical metagenomics (CMg) and the good old 16S rDNA Sanger sequencing for bacteriological diagnosis. Our work shows that they are rather complementary.

Today at Bichat medical school we honour the work of Prof. Erick Denamur on E. coli. High-level and inspiring presentations, including from Imane El Meouche from our IAME unit.

🚨SEARCHER WEBINAR🚨

Join the last webinar of 2024 with:

💊 #TommiVatanen &
💊 @etienneruppe.bsky.social

We'll be discussing #AMR trasmission and ARG prediction

🗓️ Dec 11, 2024
⏰ 02:00 PM CEST (GMT +1)

Register 👉 mdc-berlin.zoom-x.de/meeting/regi...

Details 👇👀

#MicroSky #AMRSky

indeed they're helpful in preventing from feeling alone too long!

Dear bluesky users, our research unit is currently considering migrating from X to Bluesky, could you share the pros and cons? Thanks for your ideas!