Bryan Mounce

Packing for ASV! Only the essentials! 🚙🍁🌲☃️

Does anyone else wonder what Long Legs Louise, from "Whose Bed Have Your Boots Been Under" by Shania Twain, is up to these days?

Learned how to strip paint off concrete so I guess you can call me a lumberjack now. 🌲 🎨 🖌️

a woman wearing a pearl necklace and earrings is looking at the camera ALT: a woman wearing a pearl necklace and earrings is looking at the camera

Checking eRA Commons to see if NIH still exists. 🙃

Nice write-up on our PLOS Path paper - highlighting the work of the graduate students in the lab, Yazmin and Natalie, and postdoc Delaina. 🎉

Also, the cover photo is me in the lab mixing chemicals to see what colors I could make! 🌈

First finished project of 2025! 🎉 🧶 🐼

First little virus of the new year. The goal is to make at least one per day... Gotta build up for ASV 2025 in Montréal!

Jammin’ around the Christmas tree with Maya! Wishing everyone a very happy holiday. Merry Christmas!🎄#merrychristmas #pajamarama #matchingpajamas

Speeeeeeeeedboat

Happy Birthday to Cathy, who is actually celebrating Taylor Swift's birthday today! 🎂 🎉🎈🥂🎁

I got myself a cheap pompom maker for Christmas so prepare for some pompommed yarn viruses in 2025! ❤️🧶

Rapid Screening to Identify Antivirals against Persistent and Acute Coxsackievirus B3 Infection Enteroviruses cause significant morbidity and mortality worldwide, and Coxsackievirus B3 (CVB3) is one of the most commonly reported. Coxsackieviruses establish persistent infection, characterized as ...

Yaay! It's out! Maria's paper on a drug screen we performed with acute and persistent CVB3 infection in PANC-1 cells has been published in ACS Infectious Diseases.

doi.org/10.1021/acsi...

Congrats to Maria and everyone involved! It's been fun working with these cells!

Big congrats to Maria on the acceptance of her paper!! 🥳🎊🥂🎉🎀🧀

britney spears is wearing a blue sweater and says really interesting and very cool . ALT: britney spears is wearing a blue sweater and says really interesting and very cool .

And despite being published in PLOS Pathogens, this paper is pretty light on the 𝘱𝘢𝘵𝘩𝘰𝘨𝘦𝘯 aspect. But I hope this doesn't dissuade readers! We promise it's really interesting and very cool.

elmo from sesame street is standing in front of a fire ALT: elmo from sesame street is standing in front of a fire

tldr; Polyamines mediate mitochondrial structure/function, and without polyamines, mitos are malformed and the cell can't undergo oxphos. So what's a cell to do? GLYCOLYSIS!!!!!

We had known for years that our Huh7 liver cells had these huge lipid droplets when they were depleted of polyamines - Jeremy and I first saw it when we did EM in 2019! Flash forward five years, and this project evolved!

Polyamines mediate cellular energetics and lipid metabolism through mitochondrial respiration to facilitate virus replication Author summary Cells and viruses rely on metabolic circuits to survive and replicate. The small metabolites called polyamines support cellular homeostasis by supporting mitochondrial function. Without...

Super excited about this paper out in PLOS Pathogens: journals.plos.org/plospathogen...

Polyamines, lipids, glycolysis!

Wove together a couple of these little yarn vaccines this weekend to send out on Monday!

Here to provide some yarn, color, science, and nonsense! ❤️