Alex Grenning's Avatar

Alex Grenning

@ochemgrenning.bsky.social

Associate Professor @UMN. Urgently spreading and learning the OChem Gospel. As a researcher/mentor, I want to (i.) address synthetic challenges associated with CNS disorders and (ii.) invent new reactions of general use to drug discovery.

153 Followers  |  143 Following  |  2 Posts  |  Joined: 04.01.2024  |  1.2606

Latest posts by ochemgrenning.bsky.social on Bluesky

...could serve as bioisosteres to their parent scaffold. Congrats to Dr. Morgane Mando for intellectual leadership! She is an absolute treasure of a chemist, team leader, and person! And thank you to our collaborators, Dylan Smith and Prof. Nik Boyn for invaluable contributions! 2/2

18.03.2025 04:18 — 👍 0    🔁 0    💬 0    📌 0

I am now on #bluesky! #FirstPost to report (tinyurl.com/4n4tyau7) that physicochemically altered variants of (hetero)cyclohexanecarboxylate are accessible by a 2-step 1,3-bis-trifluoromethylation then oxidative malononitrile FGI to carboxylates. We envisage that such building blocks... 1/2

18.03.2025 04:18 — 👍 19    🔁 6    💬 1    📌 3

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